Proteomic identification and characterization of bacterial factors associated with Burkholderia cenocepacia survival in a murine host

Microbiology

Volumn 153, Issue 1, 2007, Pages 206-214

  Chung, Jacqueline W ^a,b   Speert, David P ^a,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c Research Institute   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT C; BACTERIAL PROTEIN; FLAGELLIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; BURKHOLDERIA CENOCEPACIA; CYSTIC FIBROSIS; ENZYME SUBUNIT; INFECTION RESISTANCE; LUNG INFECTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN ISOLATION; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANIMALS; BACTERIAL PROTEINS; BURKHOLDERIA CEPACIA COMPLEX; BURKHOLDERIA INFECTIONS; DISEASE MODELS, ANIMAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FLAGELLIN; LUNG DISEASES; MICE; PEROXIDASES; PROTEOMICS; VIRULENCE;

BACTERIA (MICROORGANISMS); BURKHOLDERIA CENOCEPACIA; BURKHOLDERIA CEPACIA COMPLEX; MURINAE; NEGIBACTERIA;

EID: 33846304285     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.2006/000455-0     Document Type: Article

References (42)

1. Aaron, S. D., Ferris, W., Henry, D. A., Speert, D. P. & Macdonald, N. E (2000). Multiple combination bactericidal antibiotic testing for patients with cystic fibrosis infected with Burkholderia cepacia. Am J Respir Crit Care Med 161, 1206-1212.
2. Aris, R. M., Routh, J. C, LiPuma, J. J., Heath, D. G. & Gilligan, P. H. (2001). Lung transplantation for cystic fibrosis patients with Burkholderia cepacia complex. Survival linked to genomovar type. Am J Respir Crit Care Med 164, 2102-2106.
3. Chen, L., Xie, O. W. & Nathan, C. (1998). Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates. Mol Cell 1, 795-805.
4. Chernish, R. N. & Aaron, S. D. (2003). Approach to resistant gram-negative bacterial pulmonary infections in patients with cystic fibrosis. Curr Opin Pulm Med 9, 509-515.
5. Chu, K. K., Davidson, D. J., Halsey, T. K., Chung, J. W. & Speert, D. P. (2002). Differential persistence among genomovars of the Burkholderia cepacia complex in a murine model of pulmonary infection. Infect Immun 70, 2715-2720.
6. Chung, J. W., Altman, E., Beveridge, T. J. & Speert D. P. (2003). Colonial morphology of Burkholderia cepacia complex genomovar III: implications in exopolysaccharide production, pilus expression, and persistence in the mouse. Infect Immun 71, 904-909.
7. Coakley, R. D., Grubb, B. R., Paradiso, A. M., Gatzy, J. T, Johnson, L G., Kreda, S. M., O'Neal, W. K. & Boucher, R. C. (2003). Abnormal surface liquid PH regulation by cultured cystic fibrosis bronchial epithelium. Proc Natl Acad Sci U S A 100, 16083-16088.
8. Fischer, H., Widdicombe, J. H. & Illek, B. (2002). Acid secretion and proton conductance in human airway epithelium. Am J Physiol Cell Physiol 282, C736-C743.
9. Govan, J. R. & Deretic, V. (1996). Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Microbiol Rev 60, 539-574.
10. Govan, J. R., Hughes, J. E. & Vandamme, P. (1996). Burkholderia cepacia: medical, taxonomic and ecological issues. J Med Microbiol 45, 395-407.
11. Hales, B. A., Morgan, J. A., Hart, C. A. & Winstanley, C. (1998). Variation in flagellin genes and proteins of Burkholderia cepacia. J Bacteriol 180, 1110-1118.
12. Hancock R. E. & Nikaido, H. (1978). Outer membranes of gram-negative bacteria. XIX. Isolation from Pseudomonas aeruginosa PAO1 and use in reconstitution and definition of the permeability barrier. J Bacteriol 136, 381-390.
13. Hofmann, B., Hecht H. J. & Flohe, L (2002). Peroxiredoxins. Biol Chem 383, 347-364.
14. Hutchison, M. L., Poxton, I. R. & Govan, J. R. (1998). Burkholderia cepacia produces a hemolysin that is capable of inducing apoptosis and degranulation of mammalian phagocytes. Infect Immun 66, 2033-2039.
15. LiPuma, J. J. (1998). Burkholderia cepacia. Management issues and new insights. Clin Chest Med 19, 473-486, vi.
16. Loprasert, S., Sallabhan, R., Whangsuk, W. & Mongkolsuk, S. (2003). Compensatory increase in ahpC gene expression and its role in protecting Burkholderia pseudomallei against reactive nitrogen intermediates. Arch Microbiol 180, 498-502.
17. Mahenthiralingam, E., Coenye, T., Chung, J. W., Speert, D. P., Govan, J. P, Taylor, P. & Vandamme, P. (2000). Diagnostically and experimentally useful panel of strains from the Burkholderia cepacia complex. J Clin Microbiol 38, 910-913.
18. Mahenthiralingam, E., Vandamme, P., Campbell, M. E., Henry, D. A., Gravelle, A. M., Wong, L. T, Davidson, A. G., Wilcox, P. G., Nakielna, B. & Speert, D. P. (2001). Infection with Burkholderia cepacia complex genomovars in patients with cystic fibrosis: virulent transmissible strains of genomovar III can replace Burkholderia multivorans. Clin Infect Dis 33, 1469-1475.
19. Mahenthiralingam, E, Baldwin, A. & Vandamme, P. (2002). Burkholderia cepacia complex infection in patients with cystic fibrosis. J Med Microbiol 51, 533-538.
20. Mahenthiralingam, E., Urban, T. A. & Goldberg, J. B. (2005). The multifarious, multireplicon Burkholderia cepacia complex. Nat Rev Microbiol 3, 144-156.
21. Martin, D. W. & Mohr, C. D. (2000). Invasion and intracellular survival of Burkholderia cepacia. Infect Immun 68, 24-29.
22. Maurer, L. M., Yohannes, E., Bondurant, S. S., Radmacher, M. & Slonczewski, J. L. (2005). pH regulates genes for flagellar motility, catabolism, and oxidative stress in Escherichia coli K-12. J Bacteriol 187, 304-319.
23. McDougald, D., Gong, L., Srinivasan, S., Hild, E., Thompson, L., Takayama, K., Rice, S. A. & Kjelleberg, S. (2002). Defences against oxidative stress during starvation in bacteria. Antonie Van Leeuwenhoek 81, 3-13.
24. Miller, R. A. & Britigan, B. E. (1997). Role of oxidants in microbial pathophysiology. Clin Microbiol Rev 10, 1-18.
25. Poschet J., Perkett, E. & Deretic, V. (2002). Hyperacidification in cystic fibrosis: links with lung disease and new prospects for treatment. Trends Mol Med 8, 512-519.
26. Rabilloud, T. (1999). Silver staining of 2-D electrophoresis gels. Methods Mol Biol 112, 297-305.
27. Sajjan, U. S., Sun, L., Goldstein, R. & Forstner, J. F. (1995). Cable (cbl) type II pili of cystic fibrosis-associated Burkholderia (Pseudomonas) cepacia: nucleotide sequence of the cb1A major subunit pilin gene and novel morphology of the assembled appendage fibers. J Bacteriol 177, 1030-1038.
28. Schwab, U., Leigh, M., Ribeiro, C., Yankaskas, J., Burns, K., Gilligan, P., Sokol, P. & Boucher, R. (2002). Patterns of epithelial cell invasion by different species of the Burkholderia cepacia complex in well-differentiated human airway epithelia. Infect Immun 70, 4547-4555.
29. Shevchenko, A., Wilm, M., Vorm, O.. & Mann, M. (1996). Mass spectrometric sequencing of proteins in silver-stained polyacrylamide gels. Anal Chem 68, 850-858.
30. Smith, J. J., Travis, S. M., Greenberg, E. P. & Welsh, M. J. (1996). Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell 85, 229-236.
31. Sokol, P. A., Sajjan, U., Visser, M. B., Gingues, S., Forstner, J. & Kooi C. (2003). The CepIR quorum-sensing system contributes to the virulence of Burkholderia cenocepacia respiratory infections. Microbiology 149, 3649-3658.
32. Speert, D. P., Henry, D., Vandamme, P., Corey, M. & Mahenthiralingam, E. (2002). Epidemiology of Burkholderia cepacia complex in patients with cystic fibrosis, Canada. Emerg Infect Dis 8, 181-187.
33. Springer, B., Master, S., Sander, P., Zahrt, T., McFalone, M., Song, J., Papavinasasundaram, K. G., Colston, M. J., Boettger, E. & Deretic, V. (2001). Silencing of oxidative stress response in Mycobacterium tuberculosis: expression patterns of ahpC in virulent and avirulent strains and effect of ahpC inactivation. Infect Immun 69, 5967-5973.
34. Taylor, P. D., Inchley, C. J. & Gallagher, M. P. (1998). The Salmonella typhimurium AhpC polypeptide is not essential for virulence in BALB/c mice but is recognized as an antigen during infection. Infect Immun 66, 3208-3217.
35. Tomich, M., Herfst, C. A., Golden, J. W. & Mohr, C. D. (2002). Role of flagella in host cell invasion by Burkholderia cepacia. Infect Immun 70, 1799-1806.
36. Tomich, M., Griffith, A., Herfst C. A., Burns, J. L. & Mohr, C. D. (2003). Attenuated virulence of a Burkholderia cepacia type III secretion mutant in a murine model of infection. Infect Immun 71, 1405-1415.
37. Tungpradabkul, S., Wajanarogana, S., Tunpiboonsak S. & Panyim, S. (1999). PCR-RFLP analysis of the flagellin sequences for identification of Burkholderia pseudomallei and Burkholderia cepacia from clinical isolates. Mol Cell Probes 13, 99-105.
38. Urban, T. A., Griffith A., Torok A. M, Smolkin, M. E., Burns, J. L. & Goldberg, J. B. (2004). Contribution of Burkholderia cenocepacia flagella to infectivity and inflammation. Infect Immun 72, 5126-5134.
39. Visser, M. B., Majumdar, S., Hani, E. & Sokol, P. A. (2004). Importance of the ornibactin and pyochelin siderophore transport systems in Burkholderia cenocepacia lung infections. Infect Immun 72, 2850-2857.
40. Winstanley, C. & Morgan, J. A. (1997). The bacterial flagellin gene as a biomarker for detection, population genetics and epidemiological analysis. Microbiology 143, 3071-3084.
41. Winstanley, C., Detsika, M. G., Glendinning, K. J., Parsons, Y. N. & Hart, C. A. (2001). Flagellin gene PCR-RFLP analysis of a panel of strains from the Burkholderia cepacia complex. J Med Microbiol 50, 728-731.
42. Zabner, J., Smith, J. J., Karp, P. H., Widdicombe, J. H. & Welsh, M. J. (1998). Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro. Mol Cell 2, 397-403.