Vulnerability of neurons with mitochondrial dysfunction to oxidative stress is associated with down-regulation of thioredoxin

Neurochemistry International

Volumn 50, Issue 2, 2007, Pages 379-385

  Gao, Jing ^a,b   Zhu, Zeng Rong ^b   Ding, Hong Qun ^a,b   Qian, Zhongming ^d,e   Zhu, Li ^d,e   Ke, Ya ^c,d  

^a JIANGSU UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^d HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^e NANTONG UNIVERSITY   (China)

Author keywords

Alzheimer's disease (AD); Mitochondrial dysfunction; Oxidative stress; Sodium azide; Thioredoxin (Trx); Vulnerability

Indexed keywords

CYTOCHROME C OXIDASE; HYDROGEN PEROXIDE; MESSENGER RNA; SODIUM AZIDE; THIOREDOXIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; ENZYME INHIBITION; IN VITRO STUDY; MOUSE; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ELECTRON TRANSPORT COMPLEX IV; ENZYME INHIBITORS; FEMALE; HYDROGEN PEROXIDE; MEMBRANE POTENTIALS; MICE; MICE, INBRED ICR; MITOCHONDRIA; NEURONS; OXIDATIVE STRESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SODIUM AZIDE; TETRAZOLIUM SALTS; THIAZOLES; THIOREDOXIN; TIME FACTORS;

EID: 33846304236     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2006.09.007     Document Type: Article

References (28)

1. Bennett M.C., Diamond D.M., Stryker S.L., Parks J.K., and Parker Jr. W.D. Cytochrome oxidase inhibition: a novel animal model of Alzheimer's disease. J. Geriatr. Psychiatry Neurol. l5 2 (1992) 93-101
2. Bosetti F., Brizzi F., Barogi S., Mancuso M., Siciliano G., Tendi E.A., Murri L., Rapoport S.I., and Solaini G. Cytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's disease. Neurobiol. Aging 23 3 (2002) 371-376
3. Boveris A., and Chance B. The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem. J. 134 (1973) 707-716
4. Chandrasekaran K., Giordano T., Brady D.R., Stoll J., Martin L.J., and Rapoport S.I. Impairment in mitochondrial cytochrome oxidase gene expression in Alzheimer's disease. Brain Res. Mol. Brain Res. 24 (1994) 336-340
5. Cottrell D.A., Blakely E.L., Johnson M.A., Ince P.G., and Turnbull D. Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD. Neurology 57 (2001) 260-264
6. Cottrell D.A., Borthwick G.M., Johnson M.A., Ince P.G., and Turnbull D.M. The role of cytochrome c oxidase deficient hippocampal neurones in Alzheimer's disease. Neuropathol. Appl. Neurobiol. 28 5 (2002) 390-396
7. Cras P., Smith M.A., Richey P.L., Siedlak S.L., Mulvihill P., and Perry G. Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer's disease. Acta Neuropathol. 89 (1995) 291-295
8. Damier P., Hirsch E.C., Zhang P., Agid Y., and Javoy-Agid F. Glutathione peroxidase, glial cells and Parkinson's disease. Neuroscience 52 (1993) 1-6
9. Gao J., Sun H.Y., Zhu Z.R., Ding Z., and Zhu L. Antioxidant effects of dehydroepiandrosterone are related to up-regulation of thioredoxin in SH-SY5Y cells. Acta Biochim. Biophys. Sin. 37 2 (2005) 119-125
10. Gibson G.E., Sheu K.F., and Blass J.P. Abnormalities of mitochondrial enzymes in Alzheimer's disease. J. Neural. Transm. 105 (1998) 855-870
11. Ju T.C., Chen S.D., Liu C.C., and Yang D.I. Protective effects of S-nitrosoglutathione against amyloid beta-peptide neurotoxicity. Free Radic. Biol. Med. 38 7 (2005) 938-949
12. Ke Y., and Qian Z.M. Iron misregulation in the brain: a primary cause of neurodegenerative disorders. Lancet Neurol. 2 4 (2003) 246-253
13. Kish S.J., Mastrogiacomo F., Guttman M., Furukawa Y., Taanman J.W., Dozic S., Pandolfo M., Lamarche J., DiStefano L., and Chang L.J. Decreased brain protein levels of cytochrome oxidase subunits in Alzheimer's disease and in hereditary spinocerebellar ataxia disorders: a nonspecific change?. J. Neurochem. 72 2 (1999) 700-707
14. Lleo A., Greenberg S.M., and Growdon J.H. Current pharmacotherapy for Alzheimer's disease. Ann. Rev. Med. 57 (2006) 513-533
15. Lovell M.A., Xie C., and Gabbita S.P. Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease. Free Radic. Biol. Med. 28 (2000) 418-427
16. Masutani H., Bai J., Kim Y.C., and Yodoi J. Thioredoxin as a neurotrophic cofactor and an important regulator of neuroprotection. Mol. Neurobiol. 29 3 (2004) 229-242
17. Moreira P.I., Siedlak S.L., Aliev G., Zhu X., Cash A.D., Smith M.A., and Perry G. Oxidative stress mechanisms and potential therapeutics in Alzheimer disease. J. Neural. Transm. 112 7 (2005) 921-932
18. Nakamura H., Matsuda M., Furuke K., Kitaoka Y., Iwata S., Toda K., Inamoto T., Yamaoka Y., Ozawa K., and Yodoi J. Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide. Immunol. Lett. 42 1/2 (1994) 75-80
19. Nunomura A., Perry G., Pappolla M.A., Wade R., Hirai K., Chiba S., and Smith M.A. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J. Neurosci. 19 (1999) 1959-1964
20. Parker Jr. W.D., Filley C.M., and Parks J.K. Cytochrome oxidase deficiency in Alzheimer's disease. Neurology 40 (1990) 1302-1303
21. Pratico D., Uryu K., Leight S., Trojanoswki J.Q., and Lee V.M. Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J. Neurosci. 21 (2001) 4183-4187
22. Qian Z.M., and Shen X. Brain iron transport and neurodegeneration. Trends Mol. Med. 7 3 (2001) 103-108
23. Reed J.C. Mechanisms of apoptosis. Am. J. Pathol. 157 (2000) 1415-1430
24. Sagara J.I., Miura K., and Bannai S. Maintenance of neuronal glutathione by glial cells. J. Neurochem. 61 (1993) 1672-1676
25. Shibata T., Yamada T., Ishii T., Kumazawa S., Nakamura H., Masutani H., Yodoi J., and Uchida K. Thioredoxin as a molecular target of cyclopentenone prostaglandins. J. Biol. Chem. 278 28 (2003) 26046-26054
26. Swerdlow R.H., Parks J.K., Cassarino D.S., Maguire D.J., Maguire R.S., Bennett Jr. J.P., Davis R.E., and Parker Jr. W.D. Cybrids in Alzheimer's disease: a cellular model of the disease?. Neurology 49 4 (1997) 918-925
27. Szabados T., Dul C., Majtenyi K., Hargitai J., Penzes Z., and Urbanics R. A chronic Alzheimer's model evoked by mitochondrial poison sodium azide for pharmacological investigations. Behav. Brain Res. 154 1 (2004) 31-40
28. Wadia J.S., Chalmers-Redman R.M.E., Ju W.J.H., Carlile G.W., Phillips J.L., Fraser A.D., and Tatton W.G. Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: time course and modification by (-)-deprenyl. J. Neurosci. 18 (1998) 932-947