Poly(ADPR)polymerase-1 signalling of the DNA damage induced by DNA topoisomerase I poison in D54p53wt and U251p53mut glioblastoma cell lines

Pharmacological Research

Volumn 55, Issue 1, 2007, Pages 49-56

  Cimmino, Gabriella ^a   Pepe, Stefano ^a   Laus, Gianluca ^a   Chianese, Maria ^a   Prece, Daniela ^a   Penitente, Romina ^a   Quesada, Piera ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Glioblastoma cells; NU1025; p21; p53; PARP 1; TOPO I; Topotecan

Indexed keywords

8 HYDROXY 2 METHYL 4(3H) QUINAZOLINONE; DNA TOPOISOMERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN P53; TOPOTECAN;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; GLIOBLASTOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION;

APOPTOSIS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; DENSITOMETRY; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME INHIBITORS; FLOW CYTOMETRY; GLIOBLASTOMA; HUMANS; IN SITU NICK-END LABELING; INDICATORS AND REAGENTS; MUTATION; POLY(ADP-RIBOSE) POLYMERASES; QUINAZOLINES; SIGNAL TRANSDUCTION; TOPOTECAN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33846231075     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2006.10.005     Document Type: Article

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