메뉴 건너뛰기




Volumn 89, Issue 2, 2003, Pages 220-232

Central and carboxy-terminal regions of human p53 protein are essential for interaction and complex formation with PARP-1

Author keywords

NES masking; p53 export; p53 nucleocytoplasmic shuttling; p53 tetramerization

Indexed keywords

LEPTOMYCIN B; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE) POLYMERASE 1; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 0038034413     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10521     Document Type: Article
Times cited : (32)

References (35)
  • 1
    • 0034818446 scopus 로고    scopus 로고
    • Post-translational modifications and activation of p53 by genotoxic stresses
    • Appella E, Anderson CW. 2001. Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem 268:2764-2772.
    • (2001) Eur J Biochem , vol.268 , pp. 2764-2772
    • Appella, E.1    Anderson, C.W.2
  • 2
    • 0036145018 scopus 로고    scopus 로고
    • Multiple roles of the tumor suppressor p53
    • Bargonetti J, Manfredi JJn. 2002. Multiple roles of the tumor suppressor p53. Curr Opin Oncol 14:86-91.
    • (2002) Curr Opin Oncol , vol.14 , pp. 86-91
    • Bargonetti, J.1    Manfredi, J.Jn.2
  • 3
    • 0037051095 scopus 로고    scopus 로고
    • P53: An ubiquitous target of anticancer drugs
    • Blagosklonny M. 2002. P53: An ubiquitous target of anticancer drugs. Int J Cancer 98:161-166.
    • (2002) Int J Cancer , vol.98 , pp. 161-166
    • Blagosklonny, M.1
  • 4
    • 0031932910 scopus 로고    scopus 로고
    • Apparent cleavage of poly(ADP-ribose) polymerase in non-apoptotic mouse LTA cells: An artifact of cross-reactive secondary antibody
    • Budihardjo II, Poirier GG, Kaufmann SH. 1998. Apparent cleavage of poly(ADP-ribose) polymerase in non-apoptotic mouse LTA cells: An artifact of cross-reactive secondary antibody. Mol Cell Biochem 1178:245-249.
    • (1998) Mol Cell Biochem , vol.1178 , pp. 245-249
    • Budihardjo, I.I.1    Poirier, G.G.2    Kaufmann, S.H.3
  • 5
    • 0029827769 scopus 로고    scopus 로고
    • Cell cycle-dependent regulation of nuclear traffic occurs one subclass of human tumor cells and in untransformed cells
    • David-Pfeuty T, Chakrani F, Ory K, Nouvian-Doughe Y. 1996. Cell cycle-dependent regulation of nuclear traffic occurs one subclass of human tumor cells and in untransformed cells. Cell Growth Differ 7:1211-1225.
    • (1996) Cell Growth Differ , vol.7 , pp. 1211-1225
    • David-Pfeuty, T.1    Chakrani, F.2    Ory, K.3    Nouvian-Doughe, Y.4
  • 6
    • 0027500246 scopus 로고
    • Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents
    • Fritsche M, Haessler C, Brandner G. 1993. Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene 8:307-318.
    • (1993) Oncogene , vol.8 , pp. 307-318
    • Fritsche, M.1    Haessler, C.2    Brandner, G.3
  • 7
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y, Maya R, Kazaz A, Oren M. 1997. Mdm2 promotes the rapid degradation of p53. Nature 387:296-299.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 8
    • 0035081855 scopus 로고    scopus 로고
    • Segregation of nucleolar components coincides with caspase-3 activation in cisplatin-treated HeLa cells
    • Horky M, Wurzer G, Kotala V, Anton M, Vojtesek, Vacha J, Wȩsierska-Ga̧dek J. 2001. Segregation of nucleolar components coincides with caspase-3 activation in cisplatin-treated HeLa cells. J Cell Sci 114:663-670.
    • (2001) J Cell Sci , vol.114 , pp. 663-670
    • Horky, M.1    Wurzer, G.2    Kotala, V.3    Anton, M.4    Vojtesek5    Vacha, J.6    Wȩsierska-Ga̧dek, J.7
  • 9
    • 0028834902 scopus 로고
    • Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
    • Jones SN, Roe AE, Donehower LA, Bradley A. 1995. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature 378:206-208.
    • (1995) Nature , vol.378 , pp. 206-208
    • Jones, S.N.1    Roe, A.E.2    Donehower, L.A.3    Bradley, A.4
  • 10
  • 11
    • 0032533856 scopus 로고    scopus 로고
    • Functional interactions of p53 with poly(ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: Covalent poly(ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the M(r) 85,000 proteolytic fragment
    • Kumari SR, Mendoza-Alvarez H, Alvarez-Gonzalez R. 1998. Functional interactions of p53 with poly(ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: Covalent poly(ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the M(r) 85,000 proteolytic fragment. Cancer Res 58:5075-5078.
    • (1998) Cancer Res , vol.58 , pp. 5075-5078
    • Kumari, S.R.1    Mendoza-Alvarez, H.2    Alvarez-Gonzalez, R.3
  • 12
    • 0021616838 scopus 로고
    • UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells
    • Maltzman W, Czyzyk L. 1984. UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Mol Cell Biol 4:1689-1694.
    • (1984) Mol Cell Biol , vol.4 , pp. 1689-1694
    • Maltzman, W.1    Czyzyk, L.2
  • 14
    • 0028823020 scopus 로고
    • Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
    • Montes de Oca Luna R, Wagner DS, Lozano G. 1995. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 378:203-206.
    • (1995) Nature , vol.378 , pp. 203-206
    • Montes de Oca Luna, R.1    Wagner, D.S.2    Lozano, G.3
  • 15
    • 0024428508 scopus 로고
    • The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
    • Munger K, Phelps WC, Bubb V, Howley PM, Schlegel R. 1989. The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J Virol 63:4417-4421.
    • (1989) J Virol , vol.63 , pp. 4417-4421
    • Munger, K.1    Phelps, W.C.2    Bubb, V.3    Howley, P.M.4    Schlegel, R.5
  • 17
    • 0032549704 scopus 로고    scopus 로고
    • The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
    • Pomerantz J, Schreiber-Agus N. 1998. The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 92:713-723.
    • (1998) Cell , vol.92 , pp. 713-723
    • Pomerantz, J.1    Schreiber-Agus, N.2
  • 18
    • 0029587551 scopus 로고
    • Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle DE, Zindy F, Ashmun R, Sherr CJ. 1995. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 83:993-1000.
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.3    Sherr, C.J.4
  • 19
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. 1990. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63:1129-1136.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 20
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner M, Huibregtse JM, Vierstra RD, Howley PM. 1993. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75:495-505.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 21
    • 0030600536 scopus 로고    scopus 로고
    • Different cleavage pattern for poly(ADP-ribose) polymerase during necrosis and apoptosis in HL-60 cells
    • Shah GM, Shah RG, Poirier GG. 1996. Different cleavage pattern for poly(ADP-ribose) polymerase during necrosis and apoptosis in HL-60 cells. Biochem Biophys Res Commun 229:838-844.
    • (1996) Biochem Biophys Res Commun , vol.229 , pp. 838-844
    • Shah, G.M.1    Shah, R.G.2    Poirier, G.G.3
  • 23
    • 0032577703 scopus 로고    scopus 로고
    • Transient poly(ADP-ribosyl) ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis
    • Simbulan-Rosenthal CM, Rosenthal DS, Iyer S, Boulares AH, Smulson ME. 1998. Transient poly(ADP-ribosyl) ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis. J Biol Chem 273:13703-13712.
    • (1998) J Biol Chem , vol.273 , pp. 13703-13712
    • Simbulan-Rosenthal, C.M.1    Rosenthal, D.S.2    Iyer, S.3    Boulares, A.H.4    Smulson, M.E.5
  • 24
    • 0033559256 scopus 로고    scopus 로고
    • A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking
    • Stommel JM, Marchenko ND, Jimenez GS, Moll UM, Hope TJ, Wahl GM. 1999. A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking. EMBO J 18:1660-1672.
    • (1999) EMBO J , vol.18 , pp. 1660-1672
    • Stommel, J.M.1    Marchenko, N.D.2    Jimenez, G.S.3    Moll, U.M.4    Hope, T.J.5    Wahl, G.M.6
  • 25
    • 0030761351 scopus 로고    scopus 로고
    • ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase
    • Vaziri H, West MD, Allsopp RC, Davison TS, Wu YS, Arrowsmith CH, Poirier GG, Benchimol S. 1998. ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. EMBO J 17:6018-6033.
    • (1998) EMBO J , vol.17 , pp. 6018-6033
    • Vaziri, H.1    West, M.D.2    Allsopp, R.C.3    Davison, T.S.4    Wu, Y.S.5    Arrowsmith, C.H.6    Poirier, G.G.7    Benchimol, S.8
  • 26
    • 0033759112 scopus 로고    scopus 로고
    • Overexpressed poly(ADP-ribose) polymerase delays the release of rat cells from p53-mediated G(1) checkpoint
    • Wȩsierska-Ga̧dek J, Schmid G. 2000. Overexpressed poly(ADP-ribose) polymerase delays the release of rat cells from p53-mediated G(1) checkpoint. J Cell Biochem 80:85-103.
    • (2000) J Cell Biochem , vol.80 , pp. 85-103
    • Wȩsierska-Ga̧dek, J.1    Schmid, G.2
  • 27
    • 0034961678 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 regulates the stability of the wild-type p53 protein
    • Wȩsierska-Ga̧dek J, Schmid G. 2001. Poly(ADP-ribose) polymerase-1 regulates the stability of the wild-type p53 protein. Cell Mol Biol Lett 6:117-140.
    • (2001) Cell Mol Biol Lett , vol.6 , pp. 117-140
    • Wȩsierska-Ga̧dek, J.1    Schmid, G.2
  • 28
    • 0029843775 scopus 로고    scopus 로고
    • ADP-ribosylation of p53 tumor suppressor protein: Mutant but not wild-type p53 is modified
    • Wȩsierska-Ga̧dek J, Bugajska-Schretter A, Cerni C. 1996a. ADP-ribosylation of p53 tumor suppressor protein: Mutant but not wild-type p53 is modified. J Cell Biochem 62:90-101.
    • (1996) J Cell Biochem , vol.62 , pp. 90-101
    • Wȩsierska-Ga̧dek, J.1    Bugajska-Schretter, A.2    Cerni, C.3
  • 29
    • 0030065385 scopus 로고    scopus 로고
    • Autoantibodies against nucleoporin p62 constitute a novel marker of primary biliary cirrhosis
    • Wȩsierska-Ga̧dek J, Hohenauer H, Hitchman E, Penner E. 1996b. Autoantibodies against nucleoporin p62 constitute a novel marker of primary biliary cirrhosis. Gastroenterology 110:840-847.
    • (1996) Gastroenterology , vol.110 , pp. 840-847
    • Wȩsierska-Ga̧dek, J.1    Hohenauer, H.2    Hitchman, E.3    Penner, E.4
  • 30
    • 0030570439 scopus 로고    scopus 로고
    • ADP-ribosylation of wild-type p53 in vitro: Binding of p53 protein to specific p53 consensus sequence prevents its modification
    • Wȩsierska-Ga̧dek J, Schmid G, Cerni C. 1996c. ADP-ribosylation of wild-type p53 in vitro: Binding of p53 protein to specific p53 consensus sequence prevents its modification. Biochem Biophys Res Commun 224:96-102.
    • (1996) Biochem Biophys Res Commun , vol.224 , pp. 96-102
    • Wȩsierska-Ga̧dek, J.1    Schmid, G.2    Cerni, C.3
  • 31
    • 0032919454 scopus 로고    scopus 로고
    • Reduced stability of regularly spliced but not alternatively spliced p53 protein in PARP-deficient mouse fibroblasts
    • Wȩsierska-Ga̧dek J, Wang ZQ, Schmid G. 1999. Reduced stability of regularly spliced but not alternatively spliced p53 protein in PARP-deficient mouse fibroblasts. Cancer Res 59:28-34.
    • (1999) Cancer Res , vol.59 , pp. 28-34
    • Wȩsierska-Ga̧dek, J.1    Wang, Z.Q.2    Schmid, G.3
  • 32
    • 0033855685 scopus 로고    scopus 로고
    • Differential susceptibility of normal and PARP knock-out mouse fibroblasts to proteasome inhibitors
    • Wȩsierska-Ga̧dek J, Bohrn E, Herceg Z, Wang ZQ, Wurzer G. 2000. Differential susceptibility of normal and PARP knock-out mouse fibroblasts to proteasome inhibitors. J Cell Biochem 78:681-696.
    • (2000) J Cell Biochem , vol.78 , pp. 681-696
    • Wȩsierska-Ga̧dek, J.1    Bohrn, E.2    Herceg, Z.3    Wang, Z.Q.4    Wurzer, G.5
  • 33
    • 0037056222 scopus 로고    scopus 로고
    • Escape of p53 protein from E6-mediated degradation in HeLa cells after cisplatin therapy
    • Wȩsierska-Ga̧dek J, Schloffer D, Kotala V, Horky M. 2002. Escape of p53 protein from E6-mediated degradation in HeLa cells after cisplatin therapy. Int J Cancer 101:128-136.
    • (2002) Int J Cancer , vol.101 , pp. 128-136
    • Wȩsierska-Ga̧dek, J.1    Schloffer, D.2    Kotala, V.3    Horky, M.4
  • 35
    • 0033881017 scopus 로고    scopus 로고
    • Increased resistance to anticancer therapy of mouse cells lacking the poly (ADP-ribose) polymerase attributable to upregulation of the multidrug resistance gene product P-glycoprotein
    • Wurzer G, Herceg Z, Wȩsierska-Ga̧dek J. 2000. Increased resistance to anticancer therapy of mouse cells lacking the poly (ADP-ribose) polymerase attributable to upregulation of the multidrug resistance gene product P-glycoprotein. Cancer Res 60:4238-4244.
    • (2000) Cancer Res , vol.60 , pp. 4238-4244
    • Wurzer, G.1    Herceg, Z.2    Wȩsierska-Ga̧dek, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.