Expression of poly(ADP-ribose) polymerase and distribution of poly(ADP-ribosyl)ation in glioblastoma and in a glioma multicellular tumour spheroid model

Neuropathology and Applied Neurobiology

Volumn 26, Issue 6, 2000, Pages 528-535

  Wharton, S B ^a   McNelis, U ^a   Bell, H S ^a   Whittle, I R ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Glioblastoma necrosis; Poly(ADP ribose); Poly(ADP ribose) polymerase

Indexed keywords

ADENOSINE TRIPHOSPHATE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE);

ADENOSINE DIPHOSPHATE RIBOSYLATION; ADULT; AGED; ARTICLE; CELL VIABILITY; CLINICAL ARTICLE; DNA DAMAGE; ENZYME LOCALIZATION; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MULTICELLULAR SPHEROID; NECROSIS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR SPHEROID;

ADULT; AGED; CENTRAL NERVOUS SYSTEM NEOPLASMS; FEMALE; GLIOBLASTOMA; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NECROSIS; POLY ADENOSINE DIPHOSPHATE RIBOSE; POLY(ADP-RIBOSE) POLYMERASES; SPHEROIDS, CELLULAR; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED;

EID: 0034524833     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0305-1846.2000.00288.x     Document Type: Article

References (36)

1. Is necrosis helpful in the grading, of gliomas?
2. Effects of N-6 essential fatty acids on glioma invasion and growth: Experimental studies with glioma spheroids in collagen gels
3. A multicellular glioma spheroid model: Phenotypic characteristics and development of necrosis
4. Cell death in health and disease: The biology and regulation of apoptosis
5. Poly (ADP-ribose) polymerase is a B-MYB coactivator
6. Apoptosis versus necrosis. How valid a dichotomy for neurons?
7. Poly (ADProbose) polymerase is found in both the nucleus and cytoplasm of human CNS neurons
8. The cutting edge: Caspases in apoptosis and disease
9. Poly (ADP-ribosyl)ation reactions in the regulation of nuclear functions
10. Requirement of poly (ADP-ribose) polymerase in recovery from DNA damage in mice and in cells
11. (ADP-ribose)n participates in DNA excision repair
12. Poly (ADPribose) polymerase gene disruption renders mice resistant to cerebral ischaemia
13. Apoptosis in cerebral astrocytic tumours and its relationship to expression of the Bcl-2 and p53 proteins
14. Fas ligand expression in glioblastoma cell lines and primary astrocytic brain tumours
15. Glioblastoma
16. Multicellular spheroids: A three dimensional in vitro culture system to study tumour biology
17. Oxidative stress in brain ischaemia
18. Neuronal accumulation of poly (ADP-ribose) after brain ischaemia
19. Neuronal death in brain infarcts in man
20. Correlation of poly (ADP-ribose) polymerase and p53 expression levels in high-grade lymphomas
21. Activation of poly (ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischaemia
22. Detection of DNA strand breaks associated with apoptosis in human brain tumours
23. Poly (ADPribosyl) ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission
24. Poly (ADPribose) polymerase, nitric oxide and cell death
25. Apoptosis and cell proliferation in human neuroepithelial tumours
26. Apoptosis and therapy
27. Regulation of the human poly (ADP-ribose) polymerase promoter by the ETS transcription factor
28. Cell and environment interactions in tumour microregions: The multicell spheroid model
29. Preferential expression of Fas/APO1 (CD95) and apoptotic cell death in peri-necrotic cells of glioblastoma multiforme
30. Implantation of C6 astrocytoma spheroid into collagen type 1 gels: Invasive, proliferative and enzymatic characterisations
31. Apoptosis in the pathogenesis and treatment of disease
32. Necrogenesis and Fas/APO-1 (CD95) expression in primary (de novo) and secondary glioblastomas
33. The molecular biology of apoptosis
34. Poly (ADPribosyl) ation is required for p53-dependent transduction induced by radiation