메뉴 건너뛰기




Volumn 100, Issue 3, 2007, Pages 780-789

Activation of the galanin receptor 2 (GalR2) protects the hippocampus from neuronal damage

Author keywords

Akt; Extracellular signal regulated kinase; Galanin; Galanin receptor 2; Hippocampus; Neuroprotection

Indexed keywords

ENZYME INHIBITOR; GALANIN; GALANIN RECEPTOR 2; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN SERINE THREONINE KINASE;

EID: 33846226396     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04239.x     Document Type: Article
Times cited : (90)

References (44)
  • 1
    • 85176678465 scopus 로고    scopus 로고
    • Alessi D. R., Cuenda A., Cohen P., Dudley D. T. and Saltiel A. R. (1995) PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270, 27 489-27 494.
    • Alessi D. R., Cuenda A., Cohen P., Dudley D. T. and Saltiel A. R. (1995) PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270, 27 489-27 494.
  • 4
    • 0030791964 scopus 로고    scopus 로고
    • Persisting expression of galanin in axotomized mamillary and septal neurons of adult rats labeled for c-Jun and NADPH-diaphorase
    • Brecht S., Buschmann T., Grimm S., Zimmermann M. and Herdegen T. (1997) Persisting expression of galanin in axotomized mamillary and septal neurons of adult rats labeled for c-Jun and NADPH-diaphorase. Brain Res. Mol. Brain Res. 48, 7-16.
    • (1997) Brain Res. Mol. Brain Res , vol.48 , pp. 7-16
    • Brecht, S.1    Buschmann, T.2    Grimm, S.3    Zimmermann, M.4    Herdegen, T.5
  • 5
    • 0029438133 scopus 로고
    • Cloning, pharmacological characterization, and anatomical distribution of a rat cDNA encoding for a galanin receptor
    • Burgevin M. C., Loquet I., Quarteronet D. and Habert-Ortoli E. (1995) Cloning, pharmacological characterization, and anatomical distribution of a rat cDNA encoding for a galanin receptor. J. Mol. Neurosci. 6, 33-41.
    • (1995) J. Mol. Neurosci , vol.6 , pp. 33-41
    • Burgevin, M.C.1    Loquet, I.2    Quarteronet, D.3    Habert-Ortoli, E.4
  • 6
    • 1542347183 scopus 로고    scopus 로고
    • A novel role for serum response factor in neuronal survival
    • Chang S. H., Poser S. and Xia Z. (2004) A novel role for serum response factor in neuronal survival. J. Neurosci. 24, 2277-2285.
    • (2004) J. Neurosci , vol.24 , pp. 2277-2285
    • Chang, S.H.1    Poser, S.2    Xia, Z.3
  • 7
    • 0023728879 scopus 로고
    • Galanin hyperinnervates surviving neurons of the human basal nucleus of Meynert in dementias of Alzheimer's and Parkinson's disease: A hypothesis for the role of galanin in accentuating cholinergic dysfunction in dementia
    • Chan-Palay V. (1988) Galanin hyperinnervates surviving neurons of the human basal nucleus of Meynert in dementias of Alzheimer's and Parkinson's disease: a hypothesis for the role of galanin in accentuating cholinergic dysfunction in dementia. J. Comp. Neurol. 273, 543-557.
    • (1988) J. Comp. Neurol , vol.273 , pp. 543-557
    • Chan-Palay, V.1
  • 8
    • 0025059544 scopus 로고
    • Effects of central nervous system lesions on the expression of galanin: A comparative in situ hybridization and immunohistochemical study
    • Cortes R., Villar M. J., Verhofstad A. and Hokfelt T. (1990) Effects of central nervous system lesions on the expression of galanin: a comparative in situ hybridization and immunohistochemical study. Proc. Natl Acad. Sci. USA 87, 7742-7746.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 7742-7746
    • Cortes, R.1    Villar, M.J.2    Verhofstad, A.3    Hokfelt, T.4
  • 9
    • 0037121659 scopus 로고    scopus 로고
    • Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75
    • Culmsee C., Gerling N., Lehmann M., Nikolova-Karakashian M., Prehn J. H., Mattson M. P. and Krieglstein J. (2002) Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75. Neuroscience 115, 1089-1108.
    • (2002) Neuroscience , vol.115 , pp. 1089-1108
    • Culmsee, C.1    Gerling, N.2    Lehmann, M.3    Nikolova-Karakashian, M.4    Prehn, J.H.5    Mattson, M.P.6    Krieglstein, J.7
  • 10
    • 30744448642 scopus 로고    scopus 로고
    • Galanin attenuates beta-amyloid (Abeta) toxicity in rat cholinergic basal forebrain neurons
    • Ding X., MacTavish D., Kar S. and Jhamandas J. H. (2006) Galanin attenuates beta-amyloid (Abeta) toxicity in rat cholinergic basal forebrain neurons. Neurobiol. Dis. 21, 413-420.
    • (2006) Neurobiol. Dis , vol.21 , pp. 413-420
    • Ding, X.1    MacTavish, D.2    Kar, S.3    Jhamandas, J.H.4
  • 11
    • 0036488130 scopus 로고    scopus 로고
    • Potential signalling pathways underlying corticotrophin-releasing hormone-mediated neuroprotection from excitotoxicity in rat hippocampus
    • Elliott-Hunt C. R., Kazlauskaite J., Wilde G. J., Grammatopoulos D. K. and Hillhouse E. W. (2002) Potential signalling pathways underlying corticotrophin-releasing hormone-mediated neuroprotection from excitotoxicity in rat hippocampus. J. Neurochem. 80, 416-425.
    • (2002) J. Neurochem , vol.80 , pp. 416-425
    • Elliott-Hunt, C.R.1    Kazlauskaite, J.2    Wilde, G.J.3    Grammatopoulos, D.K.4    Hillhouse, E.W.5
  • 14
    • 0023425087 scopus 로고
    • Galanin inhibits acetylcholine release in the ventral hippocampus of the rat: Histochemical, autoradiographic, in vivo, and in vitro studies
    • Fisone G., Wu C. F., Consolo S., Nordstrom O., Brynne N., Bartfai T., Melander T. and Hokfelt T. (1987) Galanin inhibits acetylcholine release in the ventral hippocampus of the rat: histochemical, autoradiographic, in vivo, and in vitro studies. Proc. Natl Acad. Sci. USA 84, 7339-7343.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 7339-7343
    • Fisone, G.1    Wu, C.F.2    Consolo, S.3    Nordstrom, O.4    Brynne, N.5    Bartfai, T.6    Melander, T.7    Hokfelt, T.8
  • 15
    • 0037315101 scopus 로고    scopus 로고
    • Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons
    • Gary D. S., Milhavet O., Camandola S. and Mattson M. P. (2003) Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons. J. Neurochem. 84, 878-890.
    • (2003) J. Neurochem , vol.84 , pp. 878-890
    • Gary, D.S.1    Milhavet, O.2    Camandola, S.3    Mattson, M.P.4
  • 17
    • 33750048437 scopus 로고    scopus 로고
    • Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviour
    • Hobson S. A., Holmes F. E., Kerr N. C. H., Pope R. J. and Wynick D. (2006) Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviour. J. Neurochem. 99, 1000-1010.
    • (2006) J. Neurochem , vol.99 , pp. 1000-1010
    • Hobson, S.A.1    Holmes, F.E.2    Kerr, N.C.H.3    Pope, R.J.4    Wynick, D.5
  • 18
    • 0034633771 scopus 로고    scopus 로고
    • Holmes F. E., Mahoney S., KingV. R., Bacon A., Kerr N. C. H., PachnisV., Curtis R., Priestley J. V. and Wynick D. (2000) Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity. Proc. Natl Acad. Sci. USA 97, 11 563-11 568.
    • Holmes F. E., Mahoney S., KingV. R., Bacon A., Kerr N. C. H., PachnisV., Curtis R., Priestley J. V. and Wynick D. (2000) Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity. Proc. Natl Acad. Sci. USA 97, 11 563-11 568.
  • 20
    • 0345676509 scopus 로고    scopus 로고
    • Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3
    • Kolakowski L. F., Oneill G. P., Howard A. D. et al. (1998) Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3. J. Neurochem. 71, 2239-2251.
    • (1998) J. Neurochem , vol.71 , pp. 2239-2251
    • Kolakowski, L.F.1    Oneill, G.P.2    Howard, A.D.3
  • 21
    • 0035859885 scopus 로고    scopus 로고
    • Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: Selective actions via GalR1 and GalR2 receptors
    • Liu H. X., Brumovsky P., Schmidt R., Brown W., Payza K., Hodzic L., Pou C., Godbout C. and Hokfelt T. (2001) Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors. Proc. Natl Acad. Sci. USA 98, 9960-9964.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 9960-9964
    • Liu, H.X.1    Brumovsky, P.2    Schmidt, R.3    Brown, W.4    Payza, K.5    Hodzic, L.6    Pou, C.7    Godbout, C.8    Hokfelt, T.9
  • 22
    • 20444381722 scopus 로고    scopus 로고
    • Galanin (2-11) binds to GalR3 in transfected cell lines: Limitations for pharmacological definition of receptor subtypes
    • Lu X., Lundstrom L. and Bartfai T. (2005a) Galanin (2-11) binds to GalR3 in transfected cell lines: limitations for pharmacological definition of receptor subtypes. Neuropeptides 39, 165-167.
    • (2005) Neuropeptides , vol.39 , pp. 165-167
    • Lu, X.1    Lundstrom, L.2    Bartfai, T.3
  • 23
    • 20444412357 scopus 로고    scopus 로고
    • Distribution and differential regulation of galanin receptor subtypes in rat brain: Effects of seizure activity
    • Lu X., Mazarati A., Sanna P., Shinmei S. and Bartfai T. (2005b) Distribution and differential regulation of galanin receptor subtypes in rat brain: effects of seizure activity. Neuropeptides 39, 147-152.
    • (2005) Neuropeptides , vol.39 , pp. 147-152
    • Lu, X.1    Mazarati, A.2    Sanna, P.3    Shinmei, S.4    Bartfai, T.5
  • 24
    • 0035341268 scopus 로고    scopus 로고
    • How protein kinase C activation protects nerve cells from oxidative stress-induced cell death
    • Maher P. (2001) How protein kinase C activation protects nerve cells from oxidative stress-induced cell death. J. Neurosci. 21, 2929-2938.
    • (2001) J. Neurosci , vol.21 , pp. 2929-2938
    • Maher, P.1
  • 26
    • 0036844585 scopus 로고    scopus 로고
    • Restricted distribution of galanin receptor 3 (GalR3) mRNA in the adult rat central nervous system
    • Mennicken F., Hoffert C., Pelletier M., Ahmad S. and O'Donnell D. (2002) Restricted distribution of galanin receptor 3 (GalR3) mRNA in the adult rat central nervous system. J. Chem. Neuroanat. 24, 257-268.
    • (2002) J. Chem. Neuroanat , vol.24 , pp. 257-268
    • Mennicken, F.1    Hoffert, C.2    Pelletier, M.3    Ahmad, S.4    O'Donnell, D.5
  • 27
    • 0037233177 scopus 로고    scopus 로고
    • Estrogen receptor-mediated neuroprotection from oxidative stress requires activation of the mitogen-activated protein kinase pathway
    • Mize A. L., Shapiro R. A. and Dorsa D. M. (2003) Estrogen receptor-mediated neuroprotection from oxidative stress requires activation of the mitogen-activated protein kinase pathway. Endocrinology 144, 306-312.
    • (2003) Endocrinology , vol.144 , pp. 306-312
    • Mize, A.L.1    Shapiro, R.A.2    Dorsa, D.M.3
  • 28
    • 0033526920 scopus 로고    scopus 로고
    • Expression of the novel galanin receptor subtype GALR2 in the adult rat CNS: Distinct distribution from GALR1
    • O'Donnell. D., Ahmad. S., Wahlestedt. C. and Walker. P. (1999) Expression of the novel galanin receptor subtype GALR2 in the adult rat CNS: distinct distribution from GALR1. J. Comparative Neurol. 409, 469-481.
    • (1999) J. Comparative Neurol , vol.409 , pp. 469-481
    • O'Donnell, D.1    Ahmad, S.2    Wahlestedt, C.3    Walker, P.4
  • 29
    • 0034633760 scopus 로고    scopus 로고
    • Galanin regulates the postnatal survival of a subset of basal forebrain cholinergic neurons
    • O'Meara G., Coumis U., Ma S. Y. et al. (2000) Galanin regulates the postnatal survival of a subset of basal forebrain cholinergic neurons. Proc. Natl Acad. Sci. USA 97, 11 569-11 574.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97
    • O'Meara, G.1    Coumis, U.2    Ma, S.Y.3
  • 31
    • 0028813676 scopus 로고
    • Galanin induces a hyperpolarization of norepinephrine-containing locus coeruleus neurons in the brainstem slice
    • Pieribone V. A., Xu Z. Q., Zhang X., Grillner S., Bartfai T. and Hokfelt T. (1995) Galanin induces a hyperpolarization of norepinephrine-containing locus coeruleus neurons in the brainstem slice. Neuroscience 64, 861-874.
    • (1995) Neuroscience , vol.64 , pp. 861-874
    • Pieribone, V.A.1    Xu, Z.Q.2    Zhang, X.3    Grillner, S.4    Bartfai, T.5    Hokfelt, T.6
  • 32
    • 27644511270 scopus 로고    scopus 로고
    • The galanin-R2 agonist AR-M1896 reduces glutamate toxicity in primary neural hippocampal cells
    • Pirondi S., Fernandez M., Schmidt R., Hokfelt T., Giardino L. and Calza L. (2005) The galanin-R2 agonist AR-M1896 reduces glutamate toxicity in primary neural hippocampal cells. J. Neurochem. 95, 821-833.
    • (2005) J. Neurochem , vol.95 , pp. 821-833
    • Pirondi, S.1    Fernandez, M.2    Schmidt, R.3    Hokfelt, T.4    Giardino, L.5    Calza, L.6
  • 33
    • 0036892007 scopus 로고    scopus 로고
    • Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia
    • Rao V. L. R., Bowen K. K., Dhodda V. K., Song G. Q., Franklin J. L., Gavva N. R. and Dempsey R. J. (2002) Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia. J. Neurochem. 83, 1072-1086.
    • (2002) J. Neurochem , vol.83 , pp. 1072-1086
    • Rao, V.L.R.1    Bowen, K.K.2    Dhodda, V.K.3    Song, G.Q.4    Franklin, J.L.5    Gavva, N.R.6    Dempsey, R.J.7
  • 34
    • 4043102610 scopus 로고    scopus 로고
    • Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway
    • Sato S., Fujita N. and Tsuruo T. (2004) Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway. J. Biol. Chem. 279, 33 759-33 767.
    • (2004) J. Biol. Chem , vol.279
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 35
    • 28444496672 scopus 로고    scopus 로고
    • Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299
    • Swanson C. J., Blackburn T. P., Zhang X. et al. (2005) Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc. Natl Acad. Sci. USA 102, 17 489-17 494.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102
    • Swanson, C.J.1    Blackburn, T.P.2    Zhang, X.3
  • 36
    • 0021040521 scopus 로고
    • Galanin - a novel biologically active peptide from porcine intestine
    • Tatemoto K., Rokaeus A., Jornvall H., McDonald T. J. and Mutt V. (1983) Galanin - a novel biologically active peptide from porcine intestine. FEBS Lett. 164, 124-128.
    • (1983) FEBS Lett , vol.164 , pp. 124-128
    • Tatemoto, K.1    Rokaeus, A.2    Jornvall, H.3    McDonald, T.J.4    Mutt, V.5
  • 37
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002)
    • Vlahos C. J., Matter W. F., Hui K. Y. and Brown R. F. (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002). J. Biol. Chem. 269, 5241-5248.
    • (1994) J. Biol. Chem , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 38
    • 0031452562 scopus 로고    scopus 로고
    • Cloning and expressional characterization of a novel galanin receptor - Identification of different pharmacophores within galanin for the three galanin receptor subtypes
    • Wang S. K., He C. G., Hashemi T. and Bayne M. (1997) Cloning and expressional characterization of a novel galanin receptor - Identification of different pharmacophores within galanin for the three galanin receptor subtypes. J. Biol. Chem. 272, 31 949-31 952.
    • (1997) J. Biol. Chem , vol.272
    • Wang, S.K.1    He, C.G.2    Hashemi, T.3    Bayne, M.4
  • 39
    • 0032510702 scopus 로고    scopus 로고
    • Differential intracellular signaling of the GalR1 and GalR2 galanin receptor subtypes
    • Wang S., Hashemi T., Fried S., Clemmons A. L. and Hawes B. E. (1998) Differential intracellular signaling of the GalR1 and GalR2 galanin receptor subtypes. Biochemistry 37, 6711-6717.
    • (1998) Biochemistry , vol.37 , pp. 6711-6717
    • Wang, S.1    Hashemi, T.2    Fried, S.3    Clemmons, A.L.4    Hawes, B.E.5
  • 40
    • 0034738958 scopus 로고    scopus 로고
    • The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G (q), G (i) and G (12) proteins
    • Wittau N., Grosse R., Kalkbrenner F., Gohla A., Schultz G. and Gudermann T. (2000) The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G (q), G (i) and G (12) proteins. Oncogene 19, 4199-4209.
    • (2000) Oncogene , vol.19 , pp. 4199-4209
    • Wittau, N.1    Grosse, R.2    Kalkbrenner, F.3    Gohla, A.4    Schultz, G.5    Gudermann, T.6
  • 41
    • 0032514641 scopus 로고    scopus 로고
    • Galanin regulates prolactin release and lactotroph proliferation
    • Wynick D., Small C. J., Bacon A. et al. (1998) Galanin regulates prolactin release and lactotroph proliferation. Proc. Natl Acad. Sci. USA 95, 12 671-12 676.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95
    • Wynick, D.1    Small, C.J.2    Bacon, A.3
  • 42
    • 10744226663 scopus 로고    scopus 로고
    • Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
    • Zambrowicz B. P., Abuin A., Ramirez-Solis R. et al. (2003) Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc. Natl Acad. Sci. USA 100, 14 109-14 114.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100
    • Zambrowicz, B.P.1    Abuin, A.2    Ramirez-Solis, R.3
  • 43
    • 2542473205 scopus 로고    scopus 로고
    • Comparative signaling pathways of insulin-like growth factor-1 and brain-derived neurotrophic factor in hippocampal neurons and the role of the PI3 kinase pathway in cell survival
    • Zheng W. H. and Quirion R. (2004) Comparative signaling pathways of insulin-like growth factor-1 and brain-derived neurotrophic factor in hippocampal neurons and the role of the PI3 kinase pathway in cell survival. J. Neurochem. 89, 844-852.
    • (2004) J. Neurochem , vol.89 , pp. 844-852
    • Zheng, W.H.1    Quirion, R.2
  • 44
    • 0027513236 scopus 로고
    • Galanin reduces release of endogenous excitatory amino acids in the rat hippocampus
    • Zini S., Roisin M. P., Langel U., Bartfai T. and Ben-Ari Y. (1993) Galanin reduces release of endogenous excitatory amino acids in the rat hippocampus. Eur. J. Pharmacol. 245, 1-7.
    • (1993) Eur. J. Pharmacol , vol.245 , pp. 1-7
    • Zini, S.1    Roisin, M.P.2    Langel, U.3    Bartfai, T.4    Ben-Ari, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.