The galanin-R2 agonist AR-M1896 reduces glutamate toxicity in primary neural hippocampal cells

Journal of Neurochemistry

Volumn 95, Issue 3, 2005, Pages 821-833

  Pirondi, Stefania ^a   Fernandez, Mercedes ^a   Schmidt, Ralf ^b   Hökfelt, Tomas ^c   Giardino, Luciana ^a   Calzà, Laura ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b Astra Zeneca R and D Montreal   (Canada)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Cell death; Fos; Galanin; Galanin receptor type 2; Glutamate; Neural hippocampal cultures

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; AR M1896; BETA TUBULIN; CYTOSKELETON PROTEIN; GALANIN; GALANIN RECEPTOR 2; GALANIN[2-11] TRYPTOPHANYLTHREONYLLEUCYLASPARAGINYLSERYLALANYLGLYCYLTYROSYLLEUCYLLEUCINAMIDE; GLUTAMIC ACID; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROPEPTIDE; PROTEIN C FOS; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CELL LOSS; CELL NUCLEUS; CELL SIZE; CELL STRUCTURE; CONTROLLED STUDY; CULTURE MEDIUM; DOSE RESPONSE; DRUG RECEPTOR BINDING; EMBRYO; EXCITOTOXICITY; FEMALE; GENE EXPRESSION; HIPPOCAMPUS; IN VITRO STUDY; NEURITE; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; RAT; SYNAPSE;

ANIMALS; APOPTOSIS; CELL NUCLEUS; CELLS, CULTURED; CYTOSKELETON; DRUG INTERACTIONS; FEMALE; GALANIN; GLUTAMIC ACID; HIPPOCAMPUS; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; PEPTIDE FRAGMENTS; PREGNANCY; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, GALANIN, TYPE 2; RNA, MESSENGER; TUBULIN;

ANIMALIA;

EID: 27644511270     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03437.x     Document Type: Article

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