Virtual screening for PPAR modulators using a probabilistic neural network

ChemMedChem

Volumn 1, Issue 12, 2006, Pages 1346-1350

  Derksen, Swetlana ^a   Rau, Oliver ^a   Schneider, Petra ^b   Schubert Zsilavecz, Manfred ^a   Schneider, Gisbert ^a  

^a GOETHE UNIVERSITY   (Germany)

^b Schneider Consulting GbR   (Germany)

Author keywords

Computer chemistry; Drug design; Machine learning; PPAR agonists; Reporter gene assays

Indexed keywords

ANTIDIABETIC AGENT; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR;

ANIMAL; ARTICLE; ARTIFICIAL NEURAL NETWORK; CELL STRAIN COS1; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; PROBABILITY; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; SENSITIVITY AND SPECIFICITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; DRUG DESIGN; HYPOGLYCEMIC AGENTS; LIGANDS; MOLECULAR STRUCTURE; NEURAL NETWORKS (COMPUTER); PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PROBABILITY; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33846161653     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200600166     Document Type: Article

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