Synthesis and photophysical properties of a deazaflavin-bridged porphyrinatoiron(III) that mimics the interaction of a deazaflavin inhibitor with the heme-thiolate cofactor of cytochrome P450 3A4

Helvetica Chimica Acta

Volumn 89, Issue 12, 2006, Pages 2987-3001

  Müller, Michael A ^a   Gaplovsky, Martin ^a   Wirz, Jakob ^a   Woggon, Wolf D ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BICHROMOPHORIC COMPOUNDS; CYTOCHROME; DEAZAFLAVIN; LIVER; PHOTOPHYSICAL PROPERTIES;

ENERGY TRANSFER; ENZYME INHIBITION; ENZYMES; FLUORESCENCE; METABOLISM; SPECTROSCOPIC ANALYSIS;

IRON COMPOUNDS;

CYTOCHROME P450 3A4; DEAZAFLAVIN INHIBITOR; FERRIC ION; MIDAZOLAM; NIFEDIPINE; PORPHYRINATOIRON DERIVATIVE; RIBOFLAVIN DERIVATIVE; TESTOSTERONE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORESCENCE SPECTROSCOPY; POTENTIOMETRY; PRIORITY JOURNAL;

EID: 33846160147     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200690268     Document Type: Article

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