Effect of leptin in the treatment of obesity and influences of diet in the secretion and action of hormone;Efecto de la leptina en el tratamiento de la obesidad e influencia de la dieta en la secreción y acción de la hormona

Nutricion Hospitalaria

Volumn 21, Issue 6, 2006, Pages 686-693

  Rosado, Eliane Lopes ^a   Monteiro, J B ^b   Chaia, V ^c   Do Lago, M F ^d  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF VIÇOSA   (Brazil)

^c ESTÁCIO DE SÁ UNIVERSITY   (Brazil)

^d Hospital Ipanema   (Brazil)

Author keywords

Diet; Leptin; Obesity

Indexed keywords

LEPTIN; RECOMBINANT LEPTIN;

ARTICLE; BODY COMPOSITION; BODY WEIGHT; CALORIC INTAKE; DIET; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; FOOD INTAKE; HORMONE ACTION; HORMONE RELEASE; HORMONE RESISTANCE; HUMAN; NONHUMAN; OBESITY;

BODY WEIGHT; CLINICAL TRIALS; DIET; HUMANS; LEPTIN; OBESITY;

EID: 33846145701     PISSN: 02121611     EISSN: 16995198     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. IBGE - Instituto Brasileiro de Geografia e Estatística. Pesquisa de Orçamentos Familiares (POF): Análise da disponibilidade domiciliar de alimentos e do estado nutricional no Brasil. IBGE, Rio de Janeiro, 2004.
2. Jeanrenaud FR, Jeanrenaud B: Obesity, leptin, and the brain. N Eng J Med 1996; 334 (5): 324-5.
3. Brunner L, Nick HP, Cumin F y cols.: Leptin is a physiologically important regulator of food intake. Int J Obes 1997; 21 (12): 1152-60.
4. Considine RV: Weight regulation, leptin and growth hormone. Horm Res 1997; 48 (Supl. 5): 116-21.
5. Karlsson C, Lindell K, Svensson E y cols.: Expression of functional leptin receptors in the human ovary. J Clin Endocrinol 1997; 82 (12): 4144-8.
6. Walder K, Lewandowski P, Morton G y cols.: Leptin resistance in a polygenic, hyperleptinemic animal model of obesity and NIDDM: Psammomys obesus. Int J Obes 1999; 23 (1): 83-9.
7. Monteiro JBR: Curso de Atualização em Obesidade "Do seu Aparecimento ao seu Controle Nutricional". Viçosa - Abril/1999, pp. 22-24.
8. Corica F, Allegra A, Corsonello A y cols.: Relationship between plasma leptin levels and the tumor necrosis factor-a system in obese subjects. Int J Obes 1999; 23 (4): 355-60.
9. Trayhurn P, Hoggard N, Mercer JG, Rayner DV: Leptin: fundamental aspects. Int J Obes 1999; 23 (Supl. 1): 22-8.
10. Raben A, Astrup A: Leptin is influenced both by predisposition to obesity and diet composition. Int J Obes 2000; 24 (4): 450-9.
11. Lafontan M: Fat cells: afferent and efferent messages define new approaches to treat obesity. Annu Rev Pharmacol Toxicol 2005; 45: 119-146.
12. Mueller WM, Gregoire FM, Stanhope KL y cols.: Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. Endocrinology 1998; 139 (2): 551-8.
13. Wang J, Liu R, Hawkins M, Barzilai N, Rosseti L: A nutrient sensing pathway regulates leptin gene expression in muscle and fat. Nature 1998; 393: 684-08.
14. Havel PJ, Kasim-Karakas S, Mueller W, Jonhnson PR, Gingerich RL, Stern JS: Relationship of plasma insulin and adiposity in normal weight and over-weight women: effects of dietary fat content and sustained weight loss. J Clin Endocrinol Metab 1996; 81 (12): 4406-13.
15. Karhunen LJ, Lappalainen RI, Haffner SM y cols.: Serum leptin, food intake and preference for sugar and fat in obese women. Int J Obes 1998; 22 (8): 819-21.
16. Anaya COM, Ariza IDS: Avances en obesidad. Rev Fac Med Univ Nac Colomb 2004; 52: 270-286.
17. Palou A: Los genes de la obesidad. Nutrición y Obesidad 1998; 1 (6): 280-97.
18. Ho SC, Tai ES, Eng PHK, Ramli A, Tan CE, Fok ACK: A study in the relationships between leptin, insulin, and body fat in Asian subjects. Int J Obes 1999; 23 (3): 246-52.
19. Ahrén B, Mansson S, Gingerich RL, Havel PJ: Regulation of plasma leptin in mice: influence of age, high-fat diet, and fasting. Am J Physiol 1997; 273 (1 Pt 2): R113-20.
20. Havel PJ: Leptin production and action: relevance to energy balance in humans. Am J Clin Nutr 1998; 67 (3): 355-6.
21. Du F, Higgiinbotham DA, White BD: Food intake, energy balance and serum leptin concentrations in rats fed low-protein diets. J Nutr 2000; 130 (3): 514-21.
22. Hwa JJ, Fawzi AB, Graziano MP y cols.: Leptin increase energy expenditure and selectively promotes fat metabolism in ob/ob mice. Am J Physiol 1997; 272 (4 pt2): R1204-R9.
23. Ahima RS, Flier JS: Leptin. Annu Rev Physiol 2000; 62: 413-37.
24. Muller G, Erth J, Gerl M, Preibisch G: Leptin impairs metabolisc actions of insulin in isolated rat adipocytes. J Biol Chem 1997; 271: 10585-93.
25. Emilson V, Liu YL, Cawthorne MA, Morton NM, Davenport M: Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 1997; 46: 313-6.
26. Ostlund RE, Yang JW, Klein S, Gingerich R: Relation between plasma leptin concentration and body fat, gender, diet, age, e metabolic covariates. J Clin Endocrinol Metab 1996; 81 (11): 3909-13.
27. Grinspoon SK, Askari H, Landt ML y cols.: Effects of fasting and glucose infusion on basal and overnight leptin concentrations in normal-weight women. Am J Clin Nutr 1997; 66 (6): 1352-6.
28. Dubuc GR, Phinney SD, Stern JS, Havel PJ: Changes of serum leptin and endocrine and metabolic parameters after 7 days of energy restriction in men and women. Metabolism 1998; 47 (4): 429-34.
29. Arch JRS, Stock MJ, Trayhurn P: Leptin resistance in obese humans: does it exist and what does it mean. Int J Obes 1998; 22 (12): 1159-63.
30. Palou A, Bonet ML, Rodríguez AM: El sistema de control del peso corporal y la obesidad a la luz de la tecnología de los transgénicos. Nutrición y obesidad 2001; 4 (5): 221-51.
31. Considine RV, Sinha MK, Heiman ML y cols.: Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Eng J Med 1996; 334 (5): 292-5.
32. Hinney A, Bornscheuer A, Depenbusch M y cols.: Absence of leptin deficiency mutation in extremely obese German children and adolescents. Int J Obes 1997; 21 (12): 1190.
33. Williamson DA, Ravussina E, Wong M y cols.: Microanalysis of eating behavior of three leptin deficient adults treated with leptin therapy. Research Report. Appetite 2005; 20: 1-6.
34. Miyatake N, Takahashi K, Wada J y cols.: Changes in serum leptin concentrations in overweight Japanese men after exercise. Diabetes, Obesity and Metabolism 2004; 6: 332-337.
35. Van Dielen FMH, Veer CV, Buurman WA, Greve AWM: Leptin and soluble leptin receptor levels in obese and weight-losing individuals. J Clin Endocrinol Metab, 2002; 87 (4): 1708-1716.
36. Cohen P, Yang G, Yu X y cols.: Induction of leptin receptor expression in the liver by leptin and food deprivation. J Biol Chem 2005; 280: 10034-10039.
37. Ogier V, Ziegler O, Méjean L, Nicolas JP, Stricker-Krongrad A: Obesity is associated with decreasing levels of the circulating soluble leptin receptor in humans. Int J Obes 2002; 26: 496-503.
38. Yannakoulia M, Yiannakouris N, Bluher S, Matalas AL, Klimis-Zacas D, Mantzoros CS: Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans. J Clin Endocrinol Metab 2003; 88 (4): 1730-1736.
39. Havel PJ, Kasim-Karakas S, Dubuc GR, Mueller W, Phinney SD: Gender differences in plasma leptin concentrations. Nature Medicine 1996; 2 (9): 949-50.
40. Cooling J, Blundell J: Differences in energy expenditure and substrate oxidation between habitual high fat and low fat consumers (phenotypes). Int J Obes 1998; 22 (7): 612-18.
41. Ceddia RB, William JWN, Curi R: Comparing effects of leptin and insulin on glucose metabolism in skeletal muscle: evidence for an effect of leptin on glucose uptake and decarboxylation. Int J Obes 1999; 23 (1): 75-82.
42. Romon M, Lebel P, Fruchart J-C, Dallongeville J: Postprandial leptin response to carbohydrate and fat meals in obese women. J Am Coll Nutr 2003; 22: 247-251.
43. Scarpace PJ, Matheny M, Tümer N, Cheng KY, Zhang Y: Leptin resistance exacerbates diet-induced obesity and is associated with diminished maximal leptin signaling capacity in rats. Diabetologia 2005; 48: 1075-1083.
44. Heitmann BL, Lissner L, Osler M: Do we eat less fat, or just report so? Int J Obes 2000; 24 (4): 435-42.
45. Westerterp-Plantega MS, Wijckmans-Duijsens NEG, Verboeket-Van de Venne WPG, Graaf KH, Weststrate JA: Energy intake and body weight effects of six months reduced or full fat diets, as a function of dietary restraint. Int J Obes 1998; 22 (1): 14-22.
46. Chen MD, Song YM, Lin PY: Zinc may be a mediator of leptin production in humans. Life Sciences 2000; 66 (22): 2143-2149.
47. Baltaci AK, Mogulkoc R, Halifeoglu I: Effects of zinc deficiency and supplementation on plasma leptin levels in rats. Biol Trace Elem Res 2005; 104 (1): 41-6.
48. Documento do Consenso Latino-Americano sobre Obesidade. Ministério da Saúde, 1999.
49. Heymsfield SB, Greenberg AS, Fujioka K y cols.: Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-Escalation trial. JAMA 1999; 282: 1568-1575.
50. Lo K-M, Zhang J, Sun Y y cols.: Engineering a pharmacologically superior form of leptin for the treatment of obesity. Protein Engineering, Design & Selection 2005; 18: 1-10.
51. Shimizu H, Oh-I S, Okada S, Mori M: Inhibition of appetite by nasal leptin administration in rats. Int J Obes 2005; 29: 858-863.
52. Schulz C, Paulus K, Lehnert H: Central nervous and metabolic effects of intranasally applied leptin. Endocrinology 2004; 145 (6): 2696-2701.