Effects of pyrrolidine dithiocarbamate on healing of colonic anastomoses in the cecal ligation and puncture model of intraperitoneal sepsis in rats

World Journal of Surgery

Volumn 31, Issue 1, 2007, Pages 200-209

  Teke, Zafer ^a   Aytekin, Faruk Onder ^a   Aydin, Cagatay ^a   Kabay, Burhan ^a   Yenisey, Cigdem ^b   Sacar, Suzan ^a   Simsek, Nilufer Genc ^b   Tekin, Koray ^a  

^a PAMUKKALE UNIVERSITY   (Turkey)

^b ADNAN MENDERES UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; HYDROXYPROLINE; MALONALDEHYDE; MYELOPEROXIDASE; PYRROLIDINE DITHIOCARBAMATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CECUM; COLON ANASTOMOSIS; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; EXPERIMENTAL MODEL; INTESTINE PRESSURE; INTESTINE SURGERY; LAPAROTOMY; LIGATION; MALE; NONHUMAN; PERITONITIS; POSTOPERATIVE PERIOD; PUNCTURE; RAT; REPEATED DRUG DOSE; SEPSIS; STATISTICAL SIGNIFICANCE; SURGICAL TECHNIQUE; WOUND HEALING;

ANASTOMOSIS, SURGICAL; ANIMALS; ANTIOXIDANTS; CECUM; DISEASE MODELS, ANIMAL; GLUTATHIONE; LIGATION; LIPID PEROXIDATION; MALE; PERITONEAL DISEASES; PUNCTURES; PYRROLIDINES; RATS; RATS, WISTAR; SEPSIS; THIOCARBAMATES; WOUND HEALING;

EID: 33846139679     PISSN: 03642313     EISSN: 14322323     Source Type: Journal    
DOI: 10.1007/s00268-006-0013-9     Document Type: Article

References (62)

1. Krukowski ZH, Matheson NA. Emergency surgery for diverticular disease complicated by generalized and faecal peritonitis: a review. Br J Surg 1984;71:921-927.
2. Mealy K, Salman A, Arthur G. Definitive one-stage emergency large bowel surgery. Br J Surg 1988;75:1216-1219.
3. Roxburgh RA, Dawson JL, Yeo R. Emergency resection in treatment of diverticular disease of colon complicated by peritonitis. BMJ 1968;3:465-466.
4. Ryan P. The effect of surrounding bacterial contamination and infection upon the healing of colon wounds in dogs. Aust N Z J Surg 1969;39:107-110.
5. Irvin TT. Collagen metabolism in infected colonic anastomoses. Surg Gynecol Obstet 1976;143:220-224.
6. Orlando MD, Chendrasekhar A, Bundz S, et al. The effect of peritoneal contamination on wound strength of small bowel and colonic anastomoses. Am Surg 1999;65:673-675.
7. Remick DG, Newcomb DE, Bolgos GL, et al. Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture. Shock 2000;13:110-116.
8. Deitch EA. Rodent models of intra-abdominal infection. Shock 2005;24:19-23.
9. Orrenius S, Nobel CS, Dobb elsteen DJ, et al. Dithiocarbamates and the redox regulation of cell death. Biochem Soc Trans 1996;24:1032-1038.
10. Li C, Browder W, Kao RL. Early activation of transcription factor NF-κB during ischemia in perfused rat heart. Am J Physiol 1999;276:543-552.
11. Ross SD, Kron IL, Gangemi JJ, et al. Attenuation of lung reperfusion injury after transplantation using an inhibitor of nuclear factor-κB. Am J Physiol Lung Cell Mol Physiol 2000;297:528-536.
12. Iseki A, Kambe F, Okumura K, et al. Pyrrolidine dithiocarbamate inhibits TNF-α-dependent activation of NF-κB by increasing intracellular copper level in human aortic smooth muscle cells. Biochem Biophys Res Commun 2000;276:88-92.
13. Muller DN, Dechend R, Mervaala EMA, et al. NF-κB inhibition ameliorates angiotensin II-induced inflammatory damage in rats. Hypertension 2000;35:193-201.
14. Liu SF, Ye X, Malik AB. Inhibition of NF-κB activation by pyrrolidine dithiocarbamate prevents in vivo expression of proinflammatory genes. Circulation 1999;100:1330-1337.
15. Schreck R, Meire B, Mannel DN, et al. Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells. J Exp Med 1992;175:1181-1194.
16. Borrello S, Demple B. NF kappa B-independent transcriptional induction of the human manganese superoxide dismutase gene. Arch Biochem Biophys 1997;348:289-294.
17. Hartsfield CL, Alam J, Choi AMK. Transcriptional regulation of the heme oxygenase 1 gene by pyrrolidine dithiocarbamate. FASEB J 1998;12:1675-1682.
18. Willis D, Moore AR, Frederick R, et al. Heme oxygenase: a novel target for the modulation of the inflammatory response. Nat Med 1996;2:87-90.
19. Balla G, Jacob HS, Balla J, et al. Ferritin: a cytoprotective antioxidant stratagem of endothelium. J Biol Chem 1992;67:18128-18153.
20. Yang L, Quan S, Abraham NG. Retrovirus-mediated HO gene transfer into endothelial cells protects against oxidant induced injury. Am J Physiol 1999;277:127-133.
21. Otterbein L, Sylvester SL, Choi AM. Hemoglobin provides protection against lethal endotoxemia in rats: the role ofheme oxygenase-1. Am J Respir Cell Mol Biol 1995;13:595-601.
22. Wichterman KA, Baue A, Chaudry IH. Sepsis and septic shock: a review of laboratory models and a proposal. J Surg Res 1980;29:189-201.
23. Reijnen MM, Meis JF, Postma VA, et al. Prevention of intra-abdominal abscesses and adhesions using a hyaluronic acid solution in a rat peritonitis model. Arch Surg 1999;134:997-1001.
24. de Hingh IH, de Man BM, Lomme RM, et al. Colonic anastomotic strength and matrix metalloproteinase activity in an experimental model of bacterial peritonitis. Br J Surg 2003;90:981-988.
25. Reijnen MM, de Man BM, Hendriks T, et al. Hyaluronic acidbased agents do not affect anastomotic strength in the rat colon, in either the presence or absence of bacterial peritonitis. Br J Surg 2000;87:1222-1228.
26. Kuzu MA, Tanik A, Kale IT, et al. Effect of ischemia/reperfusion as a systemic phenomenon on anastomotic healing in the left colon. World J Surg 2000;24:990-994.
27. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-358.
28. Suzuki K, Ota H, Sasagawa S, et al. Assay method for myeloperoxidase in human polymorphonuclear leukocytes. Anal Biochem 1983;132:345-352.
29. Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys 1959;82:70-77.
30. Reddy GK, Enwemeka CS. A simplified method for the analysis of hydroxyproline in biological tissues. Clin Biochem 1996;29:225-229.
31. Regenet N, Pessaux P, Hennekinne S, et al. Primary anastomosis after intraoperative colonic lavage vs. Hartmann's procedure in generalized peritonitis complicating diverticular disease of the colon. Int J Colorectal Dis 2003;18:503-507.
32. Zorcolo L, Covotta L, Carlomagno N, et al. Safety of primary anastomosis in emergency colo-rectal surgery. Colorectal Dis 2003;5:262-269.
33. Wedell J, Banzhaf G, Chaoui R, et al. Surgical management of complicated colonic diverticulitis. Br J Surg 1997;84:380-383.
34. Biondo S, Jaurrieta E, Marti Rague J, et al. Role of resection and primary anastomosis of the left colon in the presence of peritonitis. Br J Surg 2000;87:1580-1584.
35. Runkel NS, Hinz U, Lehnert T, et al. Improved outcome after emergency surgery for cancer of the large intestine. Br J Surg 1998;85:1260-1265.
36. Salem L, Flum DR. Primary anastomosis or Hartmann's procedure for patients with diverticular peritonitis? A systematic review. Dis Colon Rectum 2004;47:1953-1964.
37. Alves A, Panis Y, Trancart D, et al. Factors associated with clinically significant anastomotic leakage after large bowel resection: multivariate analysis of 707 patients. World J Surg 2002;26:499-502.
38. Ahrendt GM, Gardner K, Barbul A. Loss of colonic structural collagen impairs healing during intra-abdominal sepsis. Arch Surg 1994;129:1179-1183.
39. Ahrendt GM, Tantry US, Barbul A. Intra-abdominal sepsis impairs colonic reparative collagen synthesis. Am J Surg 1996;171:102-107.
40. Parrillo JE. Pathogenetic mechanisms of septic shock. N Engl J Med 1993;328:1471-1477.
41. Bhattacharyya J, Biswas S, Datta AG. Mode of action of endotoxin: role of free radicals and antioxidants. Curr Med Chem 2004;11:359-368.
42. Zhang H, Slutsky AS, Vincent JL. Oxygen free radicals in ARDS, septic shock and organ dysfunction. Intensive Care Med 2000;26:474-476.
43. Dix TA, Aikens J. Mechanisms and biological significance of lipid peroxidation initiation. Chem Res Toxicol 1993;6:2-18.
44. Misra HP, Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and simple assay for superoxide dismutase. J Biol Chem 1972;247:3170-3175.
45. Dix TA, Hess KM, Medina MA, et al. Mechanism of siteselective DNA nicking by the hydrodioxyl (perhydroxyl) radical. Biochemistry 1996;35:4578-4583.
46. Beckman JS, Beckman TW, Chen J, et al. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990;87:1620-1624.
47. Pinsky MR. Antioxidant therapy for severe sepsis: promise and perspective. Crit Care Med 2003;31:2697-2698.
48. Satriano J, Schlondorff D. Activation and attenuation of transcription factor NF-kB in mouse glomerular mesangial cells in response to tumor necrosis factor-α, immunoglobulin G, and adenosine 3′:5′-cyclic monophosphate: evidence for involvement of reactive oxygen species. J Clin Invest 1994;94:1629-1636.
49. Schmidt KN, Traeckner EB, Meier B, et al. Induction of oxidative stress by okadaic acid is required for activation of transcription factor NF-kB. J Biol Chem 1995;270:136-142.
50. Liu SF, Ye X, Malik AB. In vivo inhibition of nuclear factor-kB activation prevents inducible nitric oxide synthase expression and systemic hypotension in a rat model of septic shock. J Immunol 1997;159:3976-3983.
51. Essani NA, Fisher MA, Farhood A, et al. Cytokine-induced upregulation of hepatic intercellular adhesion molecule-1 messenger RNA expression and its role in the pathophysiology of murine endotoxin shock and acute liver failure. Hepatology 1995;21:1632-1639.
52. Cuzzocrea S, McDonald MC, Mazzon E, et al. Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury. Brain Res 2000;875:96-106.
53. Graham MF, Blomquist P, Zederfeldt B. The alimentary canal. In Cohen IK, Diegelmann RF, Lindblad WJ, editors, Wound Healing: Biochemical and Clinical Aspects, 1st edition. Philadelphia, Saunders, 1992, pp 433-449.
54. Thornton FJ, Barbul A. Healing in the gastrointestinal tract. Surg Clin North Am 1997;77:549-573.
55. Kologlu M, Sayek I, Kologlu LB, et al. Effect of persistently elevated intraabdominal pressure on healing of colonic anastomoses. Am J Surg 1999;178:293-297.
56. Demirogullari B, Sönmez K, Turkyilmaz Z, et al. Comparison of consequent small bowel anastomoses after transient ischemia: an experimental study in rats. J Pediatr Surg 1998;33:91-93.
57. Jefferies H, Coster J, Khalil A, et al. Glutathione. ANZ J Surg 2003;73:517-522.
58. Nakamura S, Sugiyama S, Fujioka D, et al. Polymorphism in glutamate-cysteine ligase modifier subunit gene is associated with impairment of nitric oxide-mediated coronary vasomotor function. Circulation 2003;108:1425-1427.
59. Christensen H, Chemnitz J, Christensen BC, et al. Collagen structural organization of healing colonic anastomoses on the effect of growth hormone. Dis Colon Rectum 1995;38:1200-1205.
60. Cohen IK, Robert F, Diegelman S. Wound care and wound healing. In Schwartz SI, Shires TG, Spencer CF, editors, Principles of Surgery, 7th edition. New York, McGraw-Hill, 1999, pp 263-295.
61. Haciyanli M, Fuzun M, Unek T, et al. Does the administration route of leucovorin have any influence on the impairment of colonic healing caused by intra-peritoneal 5-fluorouracil treatment? Eur Surg Res 2001;33:80-85.
62. Irvin TT. Effects of malnutrition and hyperalimentation on wound healing. Surg Gynecol Obstet 1978;146:33-37.