Intra-abdominal sepsis impairs colonic reparative collagen synthesis

American Journal of Surgery

Volumn 171, Issue 1, 1996, Pages 102-108

  Ahrendt, Gretchen M ^a   Tantry, Udaya S ^a   Barbul, Adrian ^a,b  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b SINAI HOSPITAL OF BALTIMORE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN;

ABDOMINAL INFECTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; COLLAGEN SYNTHESIS; COLON ANASTOMOSIS; CONFERENCE PAPER; CONTROLLED STUDY; GENE EXPRESSION REGULATION; LAPAROTOMY; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SEPSIS; WOUND HEALING;

ABDOMEN; ANASTOMOSIS, SURGICAL; ANIMALS; BLOTTING, NORTHERN; COLLAGEN; COLON; DISEASE MODELS, ANIMAL; GENE EXPRESSION; INFECTION; MALE; PROLINE; PROTEIN BIOSYNTHESIS; RATS; RATS, SPRAGUE-DAWLEY; RNA; WOUND HEALING;

EID: 0030067721     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9610(99)80082-8     Document Type: Article

References (24)

1. Murray JJ. Nonelective colon resection. Surg Clin North Am. 1991;71:1187-94.
2. Koruth NM, Hunter DC, Krukowski ZH, et al. Immediate resection in emergency large bowel surgery: a 7 year audit. Br J Surg. 1985; 72:703-707.
3. Mealy K, Salman A, Arthur G. Definitive one-stage large bowel surgery. Br J Surg. 1988;75:1216-1219.
4. Schrock TR, Deveney CW, Dunphy JE. Factors contributing to leakage of colonic anastomoses. Ann Surg. 1973;177:513-518.
5. Hawley PR. Causes and prevention of colonic anastomotic breakdown. Dis Colon Rectum. 1973;16:272-277.
6. Ahrendt GM, Gardiner K, Barbul A. Loss of colonic structural collagen impairs healing during intra-abdominal sepsis. Arch Surg. 1994;129:1179-1183.
7. Irvin TT. Collagen metabolism in infected colonic anastomoses. Surg Gynecol Obstet. 1976;143:220-224.
8. Hogstrom H, Jiborn H, Zederfeldt B, et al. Influence of intraperitoneal Escherichia coli with septicemia on the healing of colonic anastomoses and skin wounds. Eur Surg Res. 1985;17:128-132.
9. Ravo B, Metwall N, Yeh J, et al. Effect of fecal loading with/without peritonitis on the healing of a colonic anastomosis: an experimental study. Eur Surg Res. 1991;23:100-107.
10. Ryan P. The effect of surrounding infection upon leaking colonic wounds: experimental studies and clinical experience. Dis Colon Rectum. 1970;13:124-126.
11. Graham MF, Blowquist P, Zederfeldt B. The alimentary canal. In: Cohen IK, Diegelman RF, Lindblad WJ, eds. Wound Healing: Biochemical and Clinical Aspects. Philadelphia: WB Saunders; 1992: 433-449.
12. Wichterman KA, Baue AE, Chaudry IH. Sepsis and septic shock-a review of laboratory models and a proposal. J Surg Res. 1980;28: 189-201.
13. Martens MFWC, Hendriks Th. Collagen synthesis in explants from rat intestine. Biochim Biophys Acta. 1989;993:252-258.
14. Lowry OH, Rosebrough NJ, Farr AL, et al. Protein measurement with the folin-phenol reagent. J Biol Chem. 1951;193:265-275.
15. Halsted WS. Circular suture of the intestine: an experimental study. Am J Med Sci. 1887;94:436-461.
16. Higashiguchi T, Noguchi Y, O'Brien W, et al. Effect of sepsis on mucosal protein synthesis in different parts of the gastrointestinal tract in rats. Clin Sci (Colch). 1994; 87(2):201-211.
17. Brasken P, Lehto M, Renvall S. Fibronectin, laminin, and collagen types I, III, IV, and V in the healing rat colon anastomosis. Ann Chir Gynaecol. 1990;79:65-71.
18. Brasken P, Lehto M, Renvall S. Changes in the connective tissue composition of the submucosal layer of colonic anastomosis. Acta Chir Scand. 1989;155:413-119.
19. Kurkinen M, Vaheri A, Roberts PJ, et al. Sequential appearance of fibronectin and collagen in experimental granulation tissue. Lab Invest. 1980;43:47-51.
20. Brasken P, Renvall S, Sandberg M. Fibronectin and collagen gene expression in healing experimental colonic anastomoses. Br J Surg. 1991;78:1048-1052.
21. Hawley PR, Faulk WP, Hunt TK, et al.. Collagenase activity in the gastrointestinal tract. Br J Surg. 1970;57:896-900.
22. Chowcat NL, Savage FJ, Lewin MR, et al. Direct measurement of collagenase in colonic anastomoses. Br J Surg. 1990;77:1284-1287.
23. Gay S, Martin GR, Muller PK, et al. Simultaneous synthesis of types I and III collagen by fibroblasts in culture. Proc Natl Acad Sci USA. 1976;73:4037-4040.
24. Bailey AJ, Shellswell GB, Duance VC. Identification and change of collagen types in differentiating myoblasts and developing chick muscle. Nature. 1979;278:67-69.