Hepatitis-B surface antigen (HBsAg) powder formulation: Process and stability assessment

Current Drug Delivery

Volumn 4, Issue 1, 2007, Pages 57-67

  Maa, Yuh Fun ^a,b   Ameri, Mahmoud ^a,b   Shu, Cassandra ^a,c   Zuleger, Cindy L ^a   Che, Jenny ^a   Osorio, Jorge E ^a   Payne, Lendon G ^a   Chen, Dexiang ^a,d  

^a PowderJect Vaccines Inc   (United States)

^b ALZA CORPORATION   (United States)

^c CELL GENESYS INC   (United States)

^d Prog Appropriate Technol Hlth   (United States)

Author keywords

Agarose beads; HBsAg; Hepatitis B surface antigen; Immunogenicity; Potency; Spray freeze drying; Spray drying

Indexed keywords

AGAROSE; DEXTRAN; HEPATITIS B SURFACE ANTIGEN; MANNITOL; NANOPARTICLE; TREHALOSE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG POTENCY; DRUG STABILITY; DRY POWDER; ENZYME IMMUNOASSAY; FEMALE; FREEZE DRYING; GUINEA PIG; IMMUNIZATION; IMMUNOGENICITY; LIGHT SCATTERING; MOISTURE; MOUSE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PREFORMULATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SKIN PENETRATION; SPRAY DRYING;

ADMINISTRATION, CUTANEOUS; ANIMALS; DISACCHARIDES; DRUG STABILITY; EXCIPIENTS; FEMALE; GUINEA PIGS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; IMMUNIZATION; IMMUNOENZYME TECHNIQUES; INJECTIONS, INTRAMUSCULAR; LYSINE; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; NANOPARTICLES; PARTICLE SIZE; POLOXAMER; POWDERS; SEPHAROSE; TECHNOLOGY, PHARMACEUTICAL;

EID: 33846078779     PISSN: 15672018     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720107779314758     Document Type: Article

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