Comparison between hepatitis B surface antigen (HBsAg) particles derived from mammalian cells (CHO) and yeast cells (Hansenula polymorpha): Composition, structure and immunogenicity

Vaccine

Volumn 15, Issue 6-7, 1997, Pages 637-647

  Diminsky, Dvorah ^a   Schirmbeck, Reinhold ^b   Reimann, Jorg ^b   Barenholz, Yechezkel ^a  

^a HEBREW UNIVERSITY   (Israel)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

hepatitis B surface antigen; immune response; lipid and protein composition; vaccine

Indexed keywords

CYSTEINE; FLUORESCEIN ISOTHIOCYANATE; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; PHOSPHOLIPID; TRINITROBENZENESULFONIC ACID;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CHO CELL; CONTROLLED STUDY; FEMALE; GENETIC ENGINEERING; HEPATITIS B VIRUS; IMMUNOGENICITY; LIPID COMPOSITION; LYMPH NODE; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; STRUCTURE ANALYSIS; SUBCUTANEOUS DRUG ADMINISTRATION; T LYMPHOCYTE ACTIVATION; TISSUE DISTRIBUTION; YEAST;

ANIMALS; CHO CELLS; CRICETINAE; FLUORESCEIN-5-ISOTHIOCYANATE; GENETIC VECTORS; HEPATITIS B SURFACE ANTIGENS; LIPIDS; MICE; MICE, INBRED BALB C; PICHIA; PROTEIN CONFORMATION; PROTEIN PRECURSORS; SULFHYDRYL COMPOUNDS; VACCINES, SYNTHETIC;

EID: 0030903829     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(96)00239-3     Document Type: Article

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