Spray-freeze-drying for protein powder preparation: Particle characterization and a case study with trypsinogen stability

Journal of Pharmaceutical Sciences

Volumn 91, Issue 10, 2002, Pages 2122-2139

  Sonner, Christine ^a   Maa, Yuh Fun ^b   Lee, Geoffrey ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b Powderject Technologies Inc   (United States)

Author keywords

Atomization; Freeze drying; Particle; Protein; Spray drying

Indexed keywords

DEXTRAN; LIQUID NITROGEN; M PROTEIN; MANNITOL; POLYSORBATE 80; TREHALOSE; TRYPSINOGEN;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL ANALYSIS; DRUG DELIVERY SYSTEM; DRUG FORMULATION; FREEZE DRYING; MOISTURE; NEBULIZATION; POROSITY; REHYDRATION; SPECTROSCOPY; WETTABILITY;

EID: 0036784625     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10204     Document Type: Article

References (33)

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