17-β estradiol administration attenuates deficits in sustained and divided attention in young ovariectomized rats and aged acyclic female rats

Behavioral Neuroscience

Volumn 120, Issue 6, 2006, Pages 1225-1234

  Barnes, P ^a,b   Staal, V ^a,b   Muir, J ^a,b   Good, M A ^a,b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

5 CSRT task; Aging; Estrogen; Ovariectomy; Sustained and divided attention

Indexed keywords

ESTRADIOL; ESTROGEN;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENTION; ATTENTION DEFICIT DISORDER; CONTROLLED STUDY; DRUG EFFECT; ESTROGEN ACTIVITY; EXPERIMENTAL RAT; FEMALE; GONAD FUNCTION; MENTAL TASK; NONHUMAN; OVARIECTOMY; RAT; RESPONSE TIME; TASK PERFORMANCE;

ACOUSTIC STIMULATION; AGING; ANALYSIS OF VARIANCE; ANIMALS; ATTENTION; BEHAVIOR, ANIMAL; CHOICE BEHAVIOR; CUES; DISCRIMINATION (PSYCHOLOGY); ENZYME-LINKED IMMUNOSORBENT ASSAY; ESTRADIOL; FEMALE; OVARIECTOMY; PHOTIC STIMULATION; RATS; REACTION TIME; SPACE PERCEPTION; TIME FACTORS;

EID: 33846066899     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.120.6.1225     Document Type: Article

References (53)

1. Baxter, M. G., & Chiba, A. A. (1999). Cognitive functions of the basal forebrain. Current Opinion in Neurobiology, 9, 178-183.
2. Chudasama, Y., Dalley, J. W., Nathwani, F., Bouger, P., & Robbins, T. W. (2004). Cholinergic modulation of visual attention and working memory: Dissociable effects of basal forebrain 192-IgG-saporin lesions and intraprefrontal infusions of scopolamine. Learning & Memory, 11, 78-86.
3. Chudasama, Y., Passetti, F., Rhodes, S. E. V., Lopian, D., Desai, A., & Robbins, T. W. (2003). Dissociable aspects of performance on the 5-choice serial reaction time task following lesions of the dorsal anterior cingulated, infralimbic and orbitofrontal cortex in the rat: Differential effects on selectivity, impulsivity and compulsivity. Behavioural Brain Research, 146, 105-119.
4. Chudasama, Y., & Robbins, T. W. (2004). Psychopharmacological approaches to modulating attention in the five-choice serial reaction time task: Implications for schizophrenia. Psychopharmacology, 174, 86-98.
5. Daniel, J. M., & Dohanich, G. P. (2001). Acetylcholine mediates the estrogen-induced increase in NMDA receptor binding in CA1 of the hippocampus and the associated improvement in working memory. Journal of Neuroscience, 21, 6949-6956.
6. Day, M., & Good, M. A. (2005). Ovariectomy-induced disruption of long-term synaptic depression in the hippocampal CA1 region in vivo is attenuated with chronic estrogen replacement. Neurobiology of Learning & Memory, 83, 13-21.
7. Dudley, S. D. (1982). Responsiveness to estradiol in central nervous system of aging female rat. Neuroscience and Biobehavioral Reviews, 6, 39-45.
8. Duffy, R., Wiseman, H., & File, S. E. (2003). Improved cognitive function in postmenopausal women after 12 weeks of consumption of a soya extract containing isoflavones. Pharmacology Biochemistry and Behavior, 75, 721-729.
9. Dumas, J., Hancur-Bucci, C., Naylor, M., Sites, C., & Newhouse, P. (2006). Estrogen treatment effects on anticholinergic-induced cognitive dysfunction in normal postmenopausal women. Neuropsychopharmacology, 9, 2065-2078.
10. File, S. E., Hartley, D. E., Elsabagh, S., Duffy, R., & Wiseman, H. (2005). Cognitive improvement after 6 weeks of soy supplements in postmenopausal women is limited to frontal lobe function. Menopause, 12, 193-201.
11. Fink, G., Sumner, B. E., Rosie, R., Grace, O., & Quinn, J. P. (1996). Estrogen control of central neurotransmission: Effect on mood, mental state, and memory. Cellular and Molecular Neurobiology, 16, 325-344.
12. Fluck, E., File, S. E., & Rymer, J. (2002). Cognitive effects of 10 years of hormone-replacement therapy with tibolone. Journal of Clinical Psychopharmacology, 22, 62-67.
13. Gibbs, R. B. (1997). Effects of estrogen on basal forebrain cholinergic neurons vary as a function of dose and duration of treatment. Brain Research, 757, 10-16.
14. Gibbs, R. B. (1998). Impairment of basal forebrain cholinergic neurons associated with aging and long-term loss of ovarian function. Experimental Neurology, 151, 289-302.
15. Gibbs, R. B., Gabor, R., Cox, T., & Johnson, D. A. (2004). Effects of raloxifene and estradiol on hippocampal acetylcholine release and spatial learning in the rat. Psychoneuroendocrinology, 29, 741-748.
16. Gibbs, R. B., Wu, D., Hersh, L. B., & Pfaff, D. W. (1994). Effects of estrogen replacement on the relative levels of choline acetyltransferase, trkA, and nerve growth factor messenger RNAs in the basal forebrain and hippocampal formation of adult rats. Experimental Neurology, 129, 70-80.
17. Goodman, M. R., Garman, E. E., Arnold, L. L., Sengelaub, D. R., & Garraghty, P. E. (2004). The effects of estradiol on avoidance learning in ovariectomized adult rats. Integrative Physiological and Behavioral Science, 39, 192-206.
18. Grilly, D. M., Simon, B. B., & Levin, E. D. (2000). Nicotine enhances stimulus detection performance of middle- and old-aged rats: A longitudinal study. Pharmacology Biochemistry and Behavior, 65, 665-670.
19. Grottick, A. J., Haman, M., Wyler, R., & Higgins, G. A. (2003). Reversal of a vigilance decrement in the aged rat by subtype-selective nicotinic ligands. Neuropsychopharmacology, 28, 880-887.
20. Grottick, A. J., & Higgins, G. A. (2002). Assessing a vigilance decrement in aged rats: Effects of prefeeding, task manipulation, and psychostimulants. Psychopharmacology, 164, 33-41.
21. Hahn, B., Shoaib, M., & Stolerman, I. P. (2003). Involvement of the prefrontal cortex but not the dorsal hippocampus in the attentionenhancing effects of nicotine in rats. Psychopharmacology, 168, 271-279.
22. Hosli, E., & Hosli, L. (1999). Cellular localization of estrogen receptors on neurons in various regions of cultured rat CNS: Coexistence with cholinergic and galanin receptors. International Journal of Developmental Neuroscience, 17, 317-330.
23. Kompoliti, K., Chu, Y., Polish, A., Roberts, J., McKay, H., Mufson, E. J., et al. (2004). Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys. Journal of Comparative Neurology, 472, 193-207.
24. Lacreuse, A. (2006). Effects of ovarian hormones on cognitive function in nonhuman primates. Neuroscience, 138, 859-867.
25. Luine, V., & Hearns, M. (1990). Spatial memory deficits in aged rats: Contributions of the cholinergic system assessed by ChAT. Brain Research, 523, 321-324.
26. Luine, V. N., Richards, S. T., Wu, V. Y., & Beck, K. D. (1998). Estradiol enhances learning and memory in a spatial memory task and effects levels of monoaminergic neurotransmitters. Hormones & Behavior, 34, 149-162.
27. Maki, P. M. (2005). Estrogen effects on the hippocampus and frontal lobes. International Journal of Fertility and Women's Medicine, 50, 67-71.
28. Mani, T. M., Bedwell, J. S., & Miller, L. S. (2005). Age-related decrements in performance on a brief continuous performance test. Archives of Clinical Neuropsychology, 20, 575-586.
29. Markowska, A. L., & Savonenko, A. V. (2002). Effectiveness of estrogen replacement in restoration of cognitive function after long-term estrogen withdrawal in aging rats. Journal of Neuroscience, 22, 10985-10995.
30. McGaughy, J., Dalley, J. W., Morrison, C. H., Everitt, B. J., & Robbins, T. W. (2002). Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a five-choice serial reaction time task. Journal of Neuroscience, 22, 1905-1913.
31. McGaughy, J., & Sarter, M. (1995). Behavioral vigilance in rats: Task validation and effects of age, amphetamine, and benzodiazepine receptor ligands. Psychopharmacology, 117, 340-357.
32. McGaughy, J., & Sarter, M. (1999). Effects of ovariectomy, 192 IgGsaporin-induced cortical cholinergic deafferentation, and administration of estradiol on sustained attention performance in rats. Behavioral Neuroscience, 113, 1216-1232.
33. Muir, J. L., Everitt, B. J., & Robbins, T. W. (1996). The cerebral cortex of the rat and visual attentional function: Dissociable effects of mediofrontal, cingulate, anterior dorsolateral, and parietal cortex lesions on a five-choice serial reaction time task. Cerebral Cortex, 6, 470-481.
34. Muir, J. L., Fischer, W., & Bjorklund, A. (1999). Decline in visual attention and spatial memory in aged rats. Neurobiology of Aging, 20, 605-615.
35. Nakazawa, K., & Ohno, Y. (2001). Modulation by estrogens and xenoestrogens of recombinant human neuronal nicotinic receptors. European Journal of Pharmacology, 430, 175-183.
36. Nilsen, J., Chen, S., & Brinton, R. D. (2002). Dual action of estrogen on glutamate-induced calcium signaling: Mechanisms requiring interaction between estrogen receptors and src/mitogen activated protein kinase pathway. Brain Research, 930, 216-234.
37. Pandaranandaka, J., Poonyachoti, S., & Kalandakanond-Thongsong, S. (2006). Anxiolytic property of estrogen related to the changes of the monoamine levels in various brain regions of ovariectomized rats. Physiology & Behavior, 87, 828-835.
38. Pongrac, J. L., Gibbs, R. B., & Defranco, D. B. (2004). Estrogen-mediated regulation of cholinergic expression in basal forebrain neurons requires extracellular-signal-regulated kinase activity. Neuroscience, 124, 809-816.
39. Portin, R., Polo-Kantola, P., Polo, O., Koskinen, T., Revonsuo, A., Irjala, K., & Erkkola, R. (1999). Serum estrogen level, attention, memory and other cognitive functions in middle-aged women. Climacteric, 2, 115-123.
40. Robbins, T. W. (2002). The 5-choice serial reaction time task: Behavioral pharmacology and functional neurochemistry. Psychopharmacology, 163, 362-380.
41. Savonenko, A. V., & Markowska, A. L. (2003). The cognitive effects of ovariectomy and estrogen replacement are modulated by aging. Neuroscience, 119, 821-830.
42. Sherwin, B. B. (2006). Estrogen and cognitive aging in women. Neuroscience, 138, 1021-1026.
43. Shughrue, P. J., Scrimo, P. J., & Merchenthaler, I. (2000). Estrogen binding and estrogen receptor characterization (ERalpha and ERbeta) in the cholinergic neurons of the rat basal forebrain. Neuroscience, 96, 41-49.
44. Singer, C. A., McMillan, P. J., Dobie, D. J., & Dorsa, D. M. (1998). Effects of estrogen replacement on choline acetyltransferase and trkA mRNA expression in the basal forebrain of aged rats. Brain Research, 789, 343-346.
45. Stevens, M. C., Clark, V. P., & Prestwood, K. M. (2005). Low-dose estradiol alters brain activity. Psychiatry Research, 139, 199-217.
46. Taylor, G. T., Bassi, C. J., & Weiss, J. (2005). Limits of learning enhancements with nicotine in old male rats. Acta Neurobiologica Experimenta, 65, 125-136.
47. Tinkler, G. P., Tobin, J. R., & Voytko, M. L. (2004). Effects of two years of estrogen loss or replacement on nucleus basalis cholinergic neurons and cholinergic fibers to the dorsolateral prefrontal and inferior parietal cortex of monkeys. Journal of Comparative Neurology, 469, 507-521.
48. Tinkler, G. P., & Voytko, M. L. (2005). Estrogen modulates cognitive and cholinergic processes in surgically menopausal monkeys. Progress in Neuropsychopharmacological and Biological Psychiatry, 29, 423-431.
49. Towart, L. A., Alves, S. E., Znamensky, V., Hayashi, S., McEwen, B. S., Milner, T. A. (2003). Subcellular relationships between cholinergic terminals and estrogen receptor-alpha in the dorsal hippocampus. Journal of Comparative Neurology, 463, 390-401.
50. Voytko, M. L. (2002). Estrogen and the cholinergic system modulate visuospatial attention in monkeys (Macaca fascicularis). Behavioral Neuroscience, 116, 187-197.
51. Woolley, C. S., & McEwen, B. S. (1994). Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism. Journal of Neuroscience, 14, 7680-7687.
52. Zhang, D., & Trudeau, V. L. (2006). Integration of membrane and nuclear estrogen receptor signaling. Comparative Biochemistry and Physiology-Part A: Molecular & Integrative Physiology, 3, 306-315.
53. Ziegler, D. R., & Gallagher, M. (2005). Spatial memory in middle-aged female rats: Assessment of estrogen replacement after ovariectomy. Brain Research, 1052, 163-173.