Significance of ectodomain cysteine boxes 2 and 3 for the activation mechanism of the thyroid-stimulating hormone receptor

Journal of Biological Chemistry

Volumn 281, Issue 42, 2006, Pages 31638-31646

  Mueller, Sandra ^a   Kleinau, Gunnar ^b   Jaeschke, Holger ^a   Neumann, Susanne ^c   Krause, Gerd ^b   Paschke, Ralf ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELLS; CONFORMATIONS; HORMONES; MUTAGENESIS;

CONFORMATIONAL INTERFERENCE; HORMONE RECEPTORS; HORMONE STIMULATION; THYROID-STIMULATING HORMONES;

AMINO ACIDS;

ALANINE; ASPARAGINE; ASPARTIC ACID; CYSTEINE; EPITOPE; GLUTAMIC ACID; LYSINE; PROLINE; THREONINE; THYROTROPIN RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; CYSTEINE; DISULFIDES; EPITOPES; FLOW CYTOMETRY; HUMANS; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, THYROTROPIN; TRYPSIN;

EID: 33845999291     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604770200     Document Type: Article

References (35)

1. Szkudlinski, M. W., Fremont, V., Ronin, C., and Weintraub, B. D. (2002) Physiol. Rev. 82, 473-502
2. Fan, Q. R., and Hendrickson, W. A. (2005) Nature 433, 269-277
3. Gudermann, T., Nurnberg, B., and Schultz, G. (1995) J. Mol. Med. 73, 51-63
4. Nagayama, Y., and Rapoport, B. (1992) Mol. Endocrinol. 6, 145-156
5. Segaloff, D. L., and Ascoli, M. (1993) Endocr. Rev. 14, 324-347
6. Simoni, M., Gromoll, J., and Nieschlag, E. (1997) Endocr. Rev. 18, 739-773
7. Themmen, A. P. N., and Huhtaniemi, I. T. (2000) Endocr. Rev. 21, 551-583
8. Parma, J., Van Sande, J., Swillens, S., Tonacchera, M., Dumont, J., and Vassart, G. (1995) Mol. Endocrinol. 9, 725-733
9. Wonerow, P., Neumann, S., Gudermann, T., and Paschke, R. (2001) J. Mol. Med. 79, 707-721
10. Smits, G., Govaerts, C., Nubourgh, I., Pardo, L., Vassart, G., and Costagliola, S. (2002) Mol. Endocrinol. 16, 722-735
11. Van Sande, J., Massart, C., Costagliola, S., Allgeier, A., Cetani, F., Vassart, G., and Dumont, J. E. (1996) Mol. Cell. Endocrinol. 119, 161-168
12. Vlaeminck-Guillem, V., Ho, S. C., Rodien, P., Vassart, G., and Costagliola, S. (2002) Mol. Endocrinol. 16, 736-746
13. Zhang, M., Tong, K. P., Fremont, V., Chen, J., Narayan, P., Puett, D., Weintraub, B. D., and Szkudlinski, M. W. (2000) Mol. Endocrinol. 141, 3514-3517
14. Zhang, M. L., Sugawa, H., Kosugi, S., and Mori, T. (1995) Biochem. Biophys. Res. Commun. 211, 205-210
15. Duprez, L., Parma, J., Costagliola, S., Hermans, J., Van Sande, J., Dumont, J. E., and Vassart, G. (1997) FEBS Lett. 409, 469-474
16. Kopp, P., Muirhead, S., Jourdain, N., Gu, W. X., Jameson, J. L., and Rodd, C. (1997) J. Clin. Investig. 100, 1634-1639
17. Gruters, A., Schoneberg, T., Biebermann, H., Krude, H., Krohn, H. P., Dralle, H., and Gudermann, T. (1998) J. Clin. Endocrinol. Metab. 83, 1431-1436
18. Jaeschke, H., Neumann, S., Kleinau, G., Mueller, S., Claus, M., Krause, G., and Paschke, R. (2006) Mol. Endocrinol. 147, 1753-1760
19. Nakabayashi, K., Kudo, M., Hsueh, A. J., and Maruo, T. (2003) Mol. Cell. Endocrinol. 202, 139-144
20. Nishi, S., Nakabayashi, K., Kobilka, B., and Hsueh, A. J. (2002) J. Biol. Chem. 277, 3958-3964
21. Bozon, V., Couture, L., Pajot-Augy, E., Richard, F., Remy, J. J., and Salesse, R. (2002) Protein Expr. Purif. 25, 114-123
22. Rapoport, B., Chazenbalk, G. D., Jaume, J. C., and McLachlan, S. M. (1998) Endocr. Rev. 19, 673-716
23. Zhang, R., Buczko, E., and Dufau, M. L. (1996) J. Biol. Chem. 271, 5755-5760
24. Ho, S. C., Van Sande, J., Lefort, A., Vassart, G., and Costagliola, S. (2001) Mol. Endocrinol. 142, 2760-2767
25. Ho, S. C., Goh, S. S., Su, Q., and Khoo, D. H. (2005) Mol. Cell. Endocrinol. 245, 158-168
26. Kleinau, G., Jaschke, H., Neumann, S., Lattig, J., Paschke, R., and Krause, G. (2004) J. Biol. Chem. 279, 51590-51600
27. Chen, C. R., Chazenbalk, G. D., McLachlan, S. M., and Rapoport, B. (2003) Mol. Endocrinol. 144, 3821-3827
28. Libert, F., Lefort, A., Gerard, C., Parmentier, M., Perret, J., Ludgate, M., Dumont, J. E., and Vassart, G. (1989) Biochem. Biophys. Res. Commun. 165, 1250-1255
29. Wonerow, P., Schoneberg, T., Schultz, G., Gudermann, T., and Paschke, R. (1998) J. Biol. Chem. 273, 7900-7905
30. Hjorth, S. A., Orskov, C., and Schwartz, T. W. (1998) Mol. Endocrinol. 12, 78-86
31. Karges, B., Gidenne, S., Aumas, C., Haddad, F., Kelly, P. A., Milgrom, E., and de Roux, N. (2005) Mol. Endocrinol. 19, 2086-2098
32. Neumann, S., Claus, M., and Paschke, R. (2005) Eur. J. Endocrinol. 152, 625-634
33. Stavrou, S. S., Zhu, Y. S., Cai, L. Q., Katz, M. D., Herrera, C., Defillo-Ricart, M., and Imperato-McGinley, J. (1998) J. Clin. Endocrinol. Metab. 83, 2091-2098
34. de Roux, N., Misrahi, M., Brauner, R., Houang, M., Carel, J. C., Granier, M., Le Bouc, Y., Ghinea, N., Boumedienne, A., Toublanc, J. E., and Milgrom, E. (1996) J. Clin. Endocrinol. Metab. 81, 4229-4235
35. Claus, M., Jaeschke, H., Kleinau, G., Neumann, S., Krause, G., and Paschke, R. (2005) Mol. Endocrinol. 146, 5197-5203