High vascular endothelial growth factor levels in NZW mice do not correlate with collagen deposition in allergic asthma

International Archives of Allergy and Immunology

Volumn 142, Issue 1, 2006, Pages 19-27

  Vasquez Pinto, Luciana M C ^a   Landgraf, Richardt G ^a   Bozza, Patrícia T ^b   Jancar, Sonia ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Airway remodeling; Eosinophil peroxidase deficiency; Lipid body; Transforming growth factor ; Vascular endothelial growth factor

Indexed keywords

ALUMINUM OXIDE; COLLAGEN; EOSIN; EOSINOPHIL PEROXIDASE; HEMATOXYLIN; LIPID; METHACHOLINE; OSMIUM; OVALBUMIN; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

AEROSOL; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS HYPERREACTIVITY; CELL ACTIVATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; EOSINOPHILIA; IMMUNIZATION; MALE; MOUSE; MUCUS; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ASTHMA; BRONCHI; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; COLLAGEN; EOSINOPHIL PEROXIDASE; EOSINOPHILIA; MALE; METHACHOLINE CHLORIDE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OVALBUMIN; TRANSFORMING GROWTH FACTOR BETA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33845951367     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000095995     Document Type: Article

References (31)

1. Kay AB, Phipps S, Robinson DS: A role for eosinophils in airway remodelling in asthma. Trends Immunol 2004;25:477-482.
2. Phipps S, et al: The relationship between allergen-induced tissue eosinophilia and markers of repair and remodeling in human atopic skin. J Immunol 2002;169:4604-4612.
3. Chiappara G, et al: Airway remodelling in the pathogenesis of asthma. Curr Opin Allergy Clin Immunol 2001;1:85-93.
4. Lee CG, et al: Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nat Med 2004;10:1095-1103.
5. Koyama S, et al: Vascular endothelial growth factor mRNA and protein expression in airway epithelial cell lines in vitro. Eur Respir J 2002;20:1449-1456.
6. Houck KA, et al: The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol Endocrinol 1991;5:1806-1814.
7. Hoshino M, Takahashi M, Aoike N: Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis. J Allergy Clin Immunol 2001;107:295-301.
8. Howell JE, McAnulty RJ: TGF-beta: its role in asthma and therapeutic potential. Curr Drug Targets 2006;7:547-565.
9. Kingston PA, et al: Adenovirus-mediated gene transfer of a secreted transforming growth factor-beta type II receptor inhibits luminal loss and constrictive remodeling after coronary angioplasty and enhances adventitial collagen deposition. Circulation 2001;104:2595-2601.
10. Ohmori J, et al: Eosinophil peroxidase deficiency in New Zealand white mice. Int Arch Allergy Immunol 1996;111:30-35.
11. Gonlugur U, Efeoglu T: Vascular adhesion and transendothelial migration of eosinophil leukocytes. Cell Tissue Res 2004;318:473-482.
12. Carlson MG, Peterson CG, Venge P: Human eosinophil peroxidase: purification and characterization. J Immunol 1985;134:1875-1879.
13. Humbles AA, et al: A critical role for eosinophils in allergic airways remodeling. Science 2004;305:1776-1779.
14. Strath M, Warren DJ, Sanderson CJ: Detection of eosinophils using an eosinophil peroxidase assay. Its use as an assay for eosinophil differentiation factors. J Immunol Methods 1985;83:209-215.
15. Chetta A, et al: Vascular endothelial growth factor up-regulation and bronchial wall remodelling in asthma. Clin Exp Allergy 2005;35:1437-1442.
16. Gama Landgraf R, Sirois P, Jancar S: Differential modulation of murine lung inflammation by bradykinin B1 and B2 selective receptor antagonists. Eur J Pharmacol 2003;460:75-83.
17. Gundersen HJ, et al: Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 1988;96:379-394.
18. Cruz-Orive LM: Particle number can be estimated using a disector of unknown thickness: the selector. J Microsc 1987;145:121-142.
19. Gundersen HJ, Jensen EB: The efficiency of systematic sampling in stereology and its prediction. J Microsc 1987;147:229-263.
20. Denzler KL, et al: Extensive eosinophil degranulation and peroxidase-mediated oxidation of airway proteins do not occur in a mouse ovalbumin-challenge model of pulmonary inflammation. J Immunol 2001;167:1672-1682.
21. Foster PS, et al: Interleukin-5 and eosinophils as therapeutic targets for asthma. Trends Mol Med 2002;8:162-167.
22. Takeda K, et al: Strain dependence of airway hyperresponsiveness reflects differences in eosinophil localization in the lung. Am J Physiol Lung Cell Mol Physiol 2001;281:L394-L402.
23. Lee JJ, et al: Defining a link with asthma in mice congenitally deficient in eosinophils. Science 2004;305:1773-1776.
24. Busse WW: Inflammation in asthma: the cornerstone of the disease and target of therapy. J Allergy Clin Immunol 1998;102:S17-S22.
25. Bozza PT, Bandeira-Melo C: Mechanisms of leukocyte lipid body formation and function in inflammation. Mem Inst Oswaldo Cruz 2005;100(suppl 1):113-120.
26. Bandeira-Melo C, Weller PF: Eosinophils and cysteinyl leukotrienes. Prostaglandins Leukot Essent Fatty Acids 2003;69:135-143.
27. Bandeira-Melo C, Bozza PT, Weller PF: The cellular biology of eosinophil eicosanoid formation and function. J Allergy Clin Immunol 2002;109:393-400.
28. Voelkel NF, Vandivier RW, Tuder RM: Vascular endothelial growth factor in the lung. Am J Physiol Lung Cell Mol Physiol 2006;290:L209-L221.
29. Leigh R, et al: Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation. Am J Respir Cell Mol Biol 2002;27:526-535.
30. Vujaskovic Z, et al: Radiation-induced hypoxia may perpetuate late normal tissue injury. Int J Radiat Oncol Biol Phys 2001;50:851-855.
31. Ferrara N: Vascular endothelial growth factor and the regulation of angiogenesis. Recent Prog Horm Res 2000;55:15-35; discussion 35-36.