Regulation of memory antibody levels: The role of persisting antigen versus plasma cell life span

Journal of Immunology

Volumn 178, Issue 1, 2007, Pages 67-76

  Gatto, Dominique ^a   Martin, Stephen W ^a   Bessa, Juliana ^a   Pellicioli, Erica ^a   Saudan, Philippe ^a   Hinton, Heather J ^a   Bachmann, Martin F ^a  

^a CYTOS BIOTECHNOLOGY AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; FOLLICULAR DENDRITIC CELL; GERMINAL CENTER; HALF LIFE TIME; IMMUNOLOGICAL MEMORY; INFECTION; LIFESPAN; LYMPHOCYTE PROLIFERATION; MEMORY CELL; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; VACCINATION; VIRUS LIKE AGENT;

EID: 33845949142     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.1.67     Document Type: Article

References (30)

1. Slifka, M. K., R. Antia, J. K. Whitmire, and R. Ahmed. 1998. Humoral immunity due to long-lived plasma cells. Immunity 8: 363-372.
2. Manz, R. A., A. Thiel, and A. Radbruch. 1997. Lifetime of plasma cells in the bone marrow. Nature 388: 133-134.
3. Crotty, S., P. Feigner, H. Davies, J. Glidewell, L. Villarreal, and R. Ahmed. 2003. Cutting edge: long-term B cell memory in humans after smallpox vaccination. J. Immunol. 171: 4969-4973.
4. Williams, G. M., and G. J. Nossal. 1966. Ontogeny of the immune response. I. The development of the follicular antigen-trapping mechanism. J. Exp. Med. 124: 47-56.
5. Mandel, T. E., R. P. Phipps, A. Abbot, and J. G. Tew. 1980. The follicular dendritic cell: long term antigen retention during immunity. Immunol. Rev. 53: 29-59.
6. Bachmann, M. F., T. M. Kundig, H. Hengartner, and R. M. Zinkernagel. 1994. Regulation of IgG antibody titers by the amount persisting of immune-complexed antigen. Eur. J. Immunol. 24: 2567-2570.
7. Bachmann, M. F., B. Odermatt, H. Hengartner, and R. M. Zinkernagel. 1996. Induction of long-lived germinal centers associated with persisting antigen after viral infection. J. Exp. Med. 183: 2259-2269.
8. Zinkernagel, R. M. 2003. On natural and artificial vaccinations. Annu. Rev. Immunol. 21: 515-546.
9. Bernasconi, N. L., E. Traggiai, and A. Lanzavecchia. 2002. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 298: 2199-2202.
10. McHeyzer-Williams, M. G., and R. Ahmed. 1999. B cell memory and the long-lived plasma cell. Curr. Opin. Immunol. 11: 172-179.
11. Manz, R. A., S. Arce, G. Cassese, A. E. Hauser, F. Hiepe, and A. Radbruch. 2002. Humoral immunity and long-lived plasma cells. Curr. Opin. Immunol. 14: 517-521.
12. Cielens, I., V. Ose, I. Petrovskis, A. Strelnikova, R. Renhofa, T. Kozlovska, and P. Pumpens. 2000. Mutilation of RNA phage Qβ virus-like particles: from icosahedrons to rods. FEBS Lett. 482: 261-264.
13. Gatto, D., C. Ruedl, B. Odermatt, and M. F. Bachmann. 2004. Rapid response of marginal zone B cells to viral particles. J. Immunol. 173: 4308-4316.
14. Gatto, D., T. Pfister, A. Jegerlehner, S. W. Martin, M. Kopf, and M. F. Bachmann. 2005. Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1. J. Exp. Med. 201: 993-1005.
15. Mackay, P., and J. L. Browning. 1998. Turning off follicular dendritic cells. Nature 395: 26-27.
16. Mackay, F., G. R. Majeau, P. Lawton, P. S. Hochman, and J. L. Browning. 1997. Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice. Eur. J. Immunol. 27: 2033-2042.
17. Tough, D. F., and J. Sprent. 1994. Turnover of naive- and memory-phenotype T cells. J. Exp. Med. 179: 1127-1135.
18. Lu, T. T., and J. G. Cyster. 2002. Integrin-mediated long-term B cell retention in the splenic marginal zone. Science 297: 409-412.
19. Ciurea, A., P. Klenerman, L. Hunziker, E. Horvath, B. Odermatt, A. F. Ochsenbein, H. Hengartner, and R. M. Zinkernagel. 1999. Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice. Proc. Natl. Acad. Sci. USA 96: 11964-11969.
20. Kozlovska, T. M., I. Cielens, D. Dreilinna, A. Dislers, V. Baumanis, V. Ose, and P. Pumpens. 1993. Recombinant RNA phage Qβ capsid particles synthesized and self-assembled in Escherichia coli. Gene 137: 133-137.
21. Sen, G., A. Q. Khan, Q. Chen, and C. M. Snapper. 2005. In vivo humoral immune responses to isolated pneumococcal polysaccharides are dependent on the presence of associated TLR ligands. J. Immunol. 175: 3084-3091.
22. Vanlandschoot, P., F. Van Houtte, P. Ulrichts, J. Tavernier, and G. Leroux-Roels. 2005. Immunostimulatory potential of hepatitis B nucleocapsid preparations: lipopolysaccharide contamination should not be overlooked. J. Gen. Virol. 86: 323-331.
23. Jegerlehner, A., T. Storni, G. Lipowsky, M. Schmid, P. Pumpens, and M. F. Bachmann. 2002. Regulation of IgG antibody responses by epitope density and CD21-mediated costimulation. Eur. J. Immunol. 32: 3305-3314.
24. Tew, J. G., J. Wu, D. Qin, S. Helm, G. F. Burton, and A. K. Szakal. 1997. Follicular dendritic cells and presentation of antigen and costimulatory signals to B cells. Immunol. Rev. 156: 39-52.
25. Haberman, A. M., and M. J. Shlomchik. 2003. Reassessing the function of immune-complex retention by follicular dendritic cells. Nat. Rev. Immunol. 3: 757-764.
26. Hannum, L. G., A. M. Haberman, S. M. Anderson, and M. J. Shlomchik. 2000. Germinal center initiation, variable region hypermutation, and mutant B cell selection without detectable immune complexes on follicular dendritic cells. J. Exp. Med. 192: 931-942.
27. Tew, J. G., T. E. Mandel, and P. L. Rice. 1980. Immune elimination and immune retention: the relationship between antigen retained in the foot and the elicitation of footpad swelling. Immunology 40: 425-433.
28. Wherry, E. J., T. C. Becker, D. Boone, M. K. Kaja, A. Ma, and R. Ahmed. 2002. Homeostatic proliferation but not the generation of virus specific memory CD8 T cells is impaired in the absence of IL-15 or IL-15Rα. Adv. Exp. Med. Biol. 512: 165-175.
29. + T cells. J. Immunol. 170: 5018-5026.
30. Weng, N. P., K. Liu, M. Catalfamo, Y. Li, and P. A. Henkart. 2002. IL-15 is a growth factor and an activator of CD8 memory T cells. Ann. NY Acad. Sci. 975: 46-56.