Homeostatic proliferation but not the generation of virus specific memory CD8 T cells is impaired in the absence of IL-15 or IL-15Rα

Advances in Experimental Medicine and Biology

Volumn 512, Issue , 2002, Pages 165-175

  John Wherry, E ^a   Becker, Todd C ^a   Boone, David ^a   Kaja, Murali Krishna ^a   Ma, Averil ^a   Ahmed, Rafi ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 15 RECEPTOR ALPHA; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL CELL; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; FEMALE; HOMEOSTASIS; IMMUNE DEFICIENCY; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; VIRUS INFECTION;

ANIMALS; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; HOMEOSTASIS; IMMUNOLOGIC MEMORY; INTERLEUKIN-15; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN SUBUNITS; RECEPTORS, INTERLEUKIN-15; RECEPTORS, INTERLEUKIN-2;

ANIMALIA; LYMPHOCYTIC CHORIOMENINGITIS VIRUS;

EID: 0036431784     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (21)

1. Lau, L. L., Jamieson, B. D., Somasundaram, T., and Ahmed, R. (1994) Nature 369(6482), 648-52.
2. Swain, S. L., Hu, H., and Huston, G. (1999) Science 286(5443), 1381-3.
3. Murali-Krishna, K., Lau, L. L., Sambhara, S., Lemonnier, F., Altman, J., and Ahmed, R. (1999) Science 286(5443), 1377-81.
4. Lodolce, J. P., Boone, D. L., Chai, S., Swain, R. E., Dassopoulos, T., Trettin, S., and Ma, A. (1998) Immunity 9(5), 669-76.
5. Kennedy, M. K., Glaccum, M., Brown, S. N., Butz, E. A., Viney, J. L., Embers, M., Matsuki, N., Charrier, K., Sedger, L., Willis, C. R., Brasel, K., Morrissey, P. J., Stocking, K., Schuh, J. C., Joyce, S., and Peschon, J. J. (2000) J Exp Med 191(5), 771-80.
6. Zhang, X., Sun, S., Hwang, L., Tough, D. F., and Sprent, J. (1998) Immunity 8(5), 591-9.
7. Ku, C. C., Murakami, M., Sakamoto, A., Kappler, J., and Marrack, P. (2000) Science 288(5466), 675-8.
8. Mattei, F., Schiavoni, G., Belardelli, F., and Tough, D. F. (2001) J Immunol 167(3), 1179-87.
9. Biron, C. A. (2001) Immunity 14(6), 661-4.
10. Umemura, M., Nishimura, H., Hirose, K., Matsuguchi, T., and Yoshikai, Y. (2001) J Immunol 167(2), 946-56.
11. Yajima, T., Nishimura, H., Ishimitsu, R., Watase, T., Busch, D. H., Pamer, E. G., Kuwano, H., and Yoshikai, Y. (2002) J Immunol 168(3), 1198-203.
12. Khan, I. A., and Casciotti, L. (1999) J Immunol 163(8), 4503-9.
13. Khan, I. A., and Kasper, L. H. (1996) J Immunol 157(5), 2103-8.
14. Tough, D. F., Borrow, P., and Sprent, J. (1996) Science 272(5270), 1947-50.
15. Fehniger, T. A., Suzuki, K., Ponnappan, A., VanDeusen, J. B., Cooper, M. A., Florea, S. M., Freud, A. G., Robinson, M. L., Durbin, J., and Caligiuri, M. A. (2001) J Exp Med 193(2), 219-31.
16. Ahmed, R., Salmi, A., Butler, L. D., Chiller, J. M., and Oldstone, M. B. (1984) J Exp Med 160(2), 521-40.
17. Murali-Krishna, K., Altman, J. D., Suresh, M., Sourdive, D. J., Zajac, A. J., Miller, J. D., Slansky, J., and Ahmed, R. (1998) Immunity 8(2), 177-87.
18. Buchmeier, M. J., and Zajac, A. J. (1999) in Persistent Viral Infections. (Ahmed R., C. I. S. Y., ed), pp. 575-605., John Wiley & Sons, Chichester, UK
19. Lodolce, J. P., Burkett, P. R., Boone, D. L., Chien, M., and Ma, A. (2001) J Exp Med 194(8), 1187-94.
20. Ohteki, T., Suzue, K., Maki, C., Ota, T., and Koyasu, S. (2001) Nat Immunol 2(12), 1138-43.
21. Giri, J. G., Kumaki, S., Ahdieh, M., Friend, D. J., Loomis, A., Shanebeck, K., DuBose, R., Cosman, D., Park, L. S., and Anderson, D. M. (1995) Embo J 14(15), 3654-63.