The autocrine TNFα signalling loop in keratinocytes requires atypical PKC species and NF-κB activation but is independent of cholesterol-enriched membrane microdomains

Biochemical Pharmacology

Volumn 73, Issue 4, 2007, Pages 526-533

  Lisby, Steen ^a   Faurschou, Annesofie ^a   Gniadecki, Robert ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Keratinocyte; Lipid rafts; NF B; Protein kinase C; Tumor necrosis factor

Indexed keywords

CHOLESTEROL; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROTEIN KINASE C; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; 12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; BETA CYCLODEXTRIN DERIVATIVE; CARBAZOLE DERIVATIVE; HELENALIN; INDOLE DERIVATIVE; INFLIXIMAB; METHYL BETA CYCLODEXTRIN; METHYL-BETA-CYCLODEXTRIN; MONOCLONAL ANTIBODY; SESQUITERPENE; UNCLASSIFIED DRUG;

ARTICLE; AUTOCRINE EFFECT; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; KERATINOCYTE; MESSENGER RNA SYNTHESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SKIN; UPREGULATION; CELL LINE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY;

ANTIBODIES, MONOCLONAL; AUTOCRINE COMMUNICATION; BETA-CYCLODEXTRINS; CARBAZOLES; CELL LINE; CHOLESTEROL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INDOLES; KERATINOCYTES; MEMBRANE MICRODOMAINS; NF-KAPPA B; PROTEIN KINASE C; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RNA, MESSENGER; SESQUITERPENES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33845933899     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.11.006     Document Type: Article

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