Changing paradigms in dermatology: Tumor necrosis factor alpha (TNF-α) blockade in psoriasis and psoriatic arthritis

Clinics in Dermatology

Volumn 21, Issue 5, 2003, Pages 392-397

  Victor, Frank C ^a   Gottlieb, Alice B ^b   Menter, Alan ^b  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ETANERCEPT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLIXIMAB; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; METHOTREXATE; PADGEM PROTEIN;

CELL PROLIFERATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; EPIDERMIS HYPERPLASIA; HUMAN; PARAKERATOSIS; PATHOGENESIS; PRIORITY JOURNAL; PSORIASIS; PSORIATIC ARTHRITIS; RANDOMIZED CONTROLLED TRIAL; REVIEW; SIDE EFFECT; SKINFOLD; T LYMPHOCYTE;

EID: 0346848881     PISSN: 0738081X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clindermatol.2003.08.015     Document Type: Article

References (48)

1. Gottlieb A.B., Bacha P., Parker K., et al. Use of the interleukin-2 fusion protein, DAB389IL-2, for the treatment of psoriasis. Dermatologic Ther. 5:1998;48-63.
2. Choy E.H.S., Panayi G.S. Cytokine pathways and joint inflammation in rheumatoid arthritis. New Eng J Med. 344:2001;907-916.
3. Duan H., Koga T., Kohda F., et al. Interleukin-8-positive neutrophils in psoriasis. J Dermatol Sci. 26:2001;119-124.
4. Giustizieri M.L., Mascia F., Frezzolini A., et al. Keratinocytes from patients with atopic dermatitis and psoriasis show a distinct chemokine production profile in response to T cell-derived cytokines. J Allergy Clin Immunol. 107:2001;871-877.
5. Komine M., Rao L.S., Freedberg I.M., et al. Interleukin-1 induces T transcription of keratin K6 in human epidermal keratinocytes. J Invest Dermatol. 116:2001;330-338.
6. Gillitzer R., Ritter U., Spandau U., et al. Differential expression of GRO-α and IL-8 mRNA in psoriasis a model for neutrophil migration and accumulation in vivo . J Invest Dermatol. 107:1996;778-782.
7. Corsini E., Bruccoleri A., Marinovich M., et al. In vitro mechanism(s) of ultraviolet-induced tumor necrosis factor-α release in a human keratinocyte cell line. Photodermatol Photoimmunol Photomed. 11:1995;112-118.
8. Komine M., Rao L.S., Kaneko T., et al. Inflammatory versus proliferative processes in epidermis. Tumor necrosis factor α induces K6b keratin synthesis through a transcriptional complex containing NFκB and C/EBPβ J Biol Chem. 275:2000;32077-32088.
9. Krueger J., Ray A., Tamm I., et al. Expression and function of interleukin-6 in epithelial cells. J Cell Biochem. 45:1991;327-334.
10. Wilmer J.L., Luster M.I. Chemical induction of interleukin-8, a pro- inflammatory chemokine, in human epidermal keratinocyte cultures and its relation to cytogenetic toxicity. Cell Biol Toxicol. 11:1995;37-50.
11. Gottlieb A.B. Psoriasis immunopathology and immunomodulation . Dermatol Clin. 19:2001;649-657.
12. Barnes P.J., Karin M. Nuclear factor-κB - A pivotal transcription factor in chronic inflammatory diseases. New Eng J Med. 336:1997;1066-1072.
13. Qin J.Z., Bacon P., Chaturvedi V., et al. Role of NF-κB activity in apoptotic response of keratinocytes mediated by interferon-γ, tumor necrosis factor-α, and tumor-necrosis-factor-related-apoptosis-inducing ligand. J Invest Dermatol. 117:2001;898-907.
14. Pfundt R., Wingens M., Bergens M., et al. TNF-α and serum induce SKALP/elafin gene expression in human keratinocytes by a p38 MAP kinase-dependent pathway. Arch Dermatol Res. 292:2000;180-187.
15. Kakurai M., Fujita N., Murata S., et al. Vasoactive intestinal peptide regulates its receptor expression and functions of human keratinocytes via type I vasoactive intestinal peptide receptors. J Invest Dermatol. 116:2001;743-749.
16. Wang Y., Jensen P.J. Regulation of the level and glycosylation state of plasminogen activator inhibitor type 2 during human keratinocyte differentiation. Differentiation. 63:1998;93-99.
17. Griffiths C.E., Voorhees J.J., Nickoloff B.J. Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal and inflamed skin modulation by recombinant gamma interferon and tumor necrosis factor . J Am Acad Dermatol. 20:1989;617-629.
18. Ackermann L., Harvima I.T. Mast cells of psoriatic and atopic dermatitis skin are positive for TNF-α and their granulation is associated with expression of ICAM-1 in the epidermis. Arch Dermatol Res. 290:1998;353-359.
19. Terajima S., Higaki M., Igarashi Y., et al. An important role of tumor necrosis factor-α in the induction of adhesion molecules in psoriasis. Arch Dermatol Res. 290:1998;246-252.
20. Li J., Mahiouz D.L., Farthing P.M., et al. Heterogeneity of ICAM-1 expression, and cytokine regulation of ICAM-1 expression, in skin and oral keratinocytes. J Oral Pathol Med. 25:1996;112-118.
21. Kainulainen V., Nelimarkka L., Jarvelainen H., et al. Suppression of syndecan-1 expression in endothelial cells by tumor necrosis factor-α J Biol Chem. 271:1996;18759-18766.
22. Fujisawa H., Nakayama K., Nomura T., et al. Interleukin-1 and lipopolysaccharide enhance intercellular adhesion molecule-1 expression in cell lines of human squamous cell carcinoma. J Dermatol Sci. 14:1997;109-114.
23. Frank S., Stallmeyer B., Kampfer H., et al. Nitric oxide triggers enhanced induction of vascular endothelial growth factor expression in cultured keratinocytes (HaCaT) and during cutaneous wound repair. FASEB J. 13:1999;2002-2014.
24. Journal: Frank S, Kolb N, Werner ER, et al. Coordinated induction of inducible nitric oxide synthase and GTP-cyclohydrolase I is dependent on inflammatory cytokines and interferon-γ in HaCaT keratinocytes: implications for the model of cutaneous wound repair. J Invest Dermatol 1998;111:1065-71.
25. Journal: Yamaoka J, Kume T, Akaike A, et al. Suppressive effect of zinc ion on iNOS expression induced by interferon-γ or tumor necrosis factor- α in murine keratinocytes. J Dermatol Sci 2000;23:27-35.
26. Kimber I., Holliday M.R., Dearman R.J. Cytokine regulation of chemical sensitization. Toxicol Lett. 82-83:1995;491-496.
27. Schwarzenberger K., Udey M.C. Contact allergens and epidermal proinflammatory cytokines modulate Langerhans cell E-cadherin expression in situ. J Invest Dermatol. 106:1996;553-558.
28. Osada A., Nakashima H., Furue M., et al. Up-regulation of CD44 expression by tumor necrosis factor-α is neutralized by interleukin-10 in Langerhans cells. J Invest Dermatol. 105:1995;124-127.
29. Ettehadi P., Greaves M.W., Wallach D., et al. Elevated tumour necrosis factor-α (TNF-α) biological activity in psoriatic skin lesions. Clin Exp Immunol. 96:1994;146-151.
30. Mizutani H., Ohmoto Y., Mizutani T., et al. Role of increased production of monocytes TNF-α, IL-1β, and IL-6 in psoriasis relation to focal infection, disease activity and responses to treatments . J Dermatol Sci. 14:1997;145-153.
31. Kristensen M., Chu C.Q., Eedy D.J., et al. Localization of tumour necrosis factor-α (TNF-α) and its receptors in normal and psoriatic skin epidermal cells express the 55-kD but not the 75-kD TNF receptor . Clin Exp Immunol. 94:1993;354-362.
32. Dembic Z., Loetscher H., Gubler U., et al. Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences. Cytokine. 2:1990;231-237.
33. LaDuca J.R., Gaspari A.A. Targeting tumour necrosis factor α new drugs used to modulate inflammatory diseases . Dermatol Clin. 19:2001;617-635.
34. Kruppa G., Thoma B., Machleidt T., et al. Inhibition of tumor necrosis factor (TNF)-mediated NF-κB activation by selective blockade of the human 55-kDa TNF receptor. J Immunol. 148:1992;3152-3157.
35. Hill G.R., Teshima T., Rebel V.I., et al. The p55 TNF-α receptor plays a critical role in T cell alloreactivity. J Immunol. 164:2000;656-663.
36. Sugano M., Tsuchida K., Tomita H., et al. Increased proliferation of endothelial cells with overexpression of soluble TNF-α receptor I gene. Atherosclerosis. 162:2002;77-84.
37. Wang B., Fujisawa H., Zhuang L., et al. Depressed Langerhans cell migration and reduced contact hypersensitivity response in mice lacking TNF receptor p75. J Immunol. 159:1997;6148-6155.
38. Tartaglia L.A., Goeddel D.V., Reynolds C., et al. Stimulation of human T cell proliferation by specific activation of the 75-kDa tumor necrosis factor receptor. J Immunol. 151:1993;4637-4641.
39. Vandenabeele P., Declercq W., Vercammen D., et al. Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma. J Exp Med. 176:1992;1015-1024.
40. Knight D.M., Trinh H., Le J., et al. Construction and initial characterization of a mouse-human chimeric anti-TNF antibody. Mol Immunol. 30:1993;1443-1453.
41. Scallon B.J., Moore M.A., Trinh H., et al. Chimeric anti-TNF-α monoclonal anti-body cA2 binds recombinant transmembrane TNF-α and activates immune effector functions. Cytokine. 7:1995;251-259.
42. Oh C.J., Das K.M., Gottlieb A.B. Treatment with anti-tumor necrosis factor-α (TNF-α) monoclonal antibody dramatically decreases the clinical activity of psoriasis lesions. J Am Acad Dermatol. 42:2000;829-830.
43. Chaudhari U., Romano P., Mulcahy L.D., et al. Efficacy and safety of infliximab monotherapy for plaque-type psoriasis a randomized trial . Lancet. 357:2001;1842-1847.
44. Ogilvie A.L.J., Antoni C., Dechant C., et al. Treatment of psoriatic arthritis with antitumour necrosis factor-α antibody clears skin lesions of psoriasis resistant to treatment with methotrexate. Br J Dermatology. 144:2001;587-589.
45. Antoni C., Dechant C., Ogilvie A., et al. Successful treatment of psoriatic arthritis with infliximab in an MRI-controlled study. J Rheumatol. 27:(suppl 59):2000;24.
46. Gottlieb A.B., Lowe N.J., Matheson R.T., et al. Efficacy of etanercept in patients with psoriasis. Ann Dermatol Venereol. 129:2002;1S280.
47. Mease P.J., Goffe B.S., Metz J., et al. Etanercept in the treatment of psoriatic arthritis and psoriasis a randomised trial . Lancet. 356:2000;385-390.
48. Mease P., Kivitz A., Burch F., et al. Improvement in disease activity in patients with psoriatic arthritis receiving etanercept (Enbrel) results of a phase 3 multicenter clinical trial . Arthritis Rheumatol. 44:2001;S90.