Entropic folding pathway of human epidermal growth factor explored by disulfide scrambling and amplified collective motion simulations

Biochemistry

Volumn 45, Issue 51, 2006, Pages 15269-15278

  Zhang, Zhiyong ^a   Boyle, Paul C ^a   Lu, Bao Yuan ^b   Chang, Jui Yoa ^b   Wriggers, Willy ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; COMPUTER SIMULATION; CONFORMATIONS; MOLECULAR DYNAMICS; PROTEINS;

AMPLIFIED COLLECTIVE MOTION (ACM); EGF RECEPTOR (EGFR); EPIDERMAL GROWTH FACTOR (EGF); MOTION SIMULATIONS;

CELL MEMBRANES;

CYSTEINE; DISULFIDE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MUTANT PROTEIN; SERINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; DISULFIDE BOND; ENTROPY; ISOMER; MOLECULAR DYNAMICS; MOLECULAR STABILITY; MOTION; MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; RECEPTOR BINDING; REGULATORY MECHANISM; SIMULATION; STANDARD; TECHNIQUE; WILD TYPE;

AMINO ACID SEQUENCE; COMPUTER SIMULATION; DISULFIDES; ENTROPY; EPIDERMAL GROWTH FACTOR; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 33845933462     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0615083     Document Type: Article

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