A Major Kinetic Trap for the Oxidative Folding of Human Epidermal Growth Factor

Journal of Biological Chemistry

Volumn 276, Issue 7, 2001, Pages 4845-4852

  Chang, Jui Yoa ^a   Li, Li ^a   Lai, Por Hsiung ^b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b Protein Institute Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOMERS; PROTEINS; REACTION KINETICS; SULFUR COMPOUNDS;

HUMAN EPIDERMAL GROWTH FACTOR (EGF);

BIOCHEMISTRY;

APROTININ; CYSTEINE DERIVATIVE; DISULFIDE; EPIDERMAL GROWTH FACTOR; HIRUDIN; HIRUDIN DERIVATIVE;

ARTICLE; DISULFIDE BOND; KINETICS; OXIDATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; ANIMAL; CATTLE; CHEMISTRY; COMPARATIVE STUDY; HUMAN; MASS SPECTROMETRY; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; PROTEIN TERTIARY STRUCTURE;

BOVINAE;

AMINO ACID SEQUENCE; ANIMALS; APROTININ; CATTLE; DISULFIDES; EPIDERMAL GROWTH FACTOR; HIRUDINS; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0035895917     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M005160200     Document Type: Article

References (25)

1. Creighton, T. E. (1978) Prog. Biophys. Mol. Biol. 33, 231-297
2. Creighton, T. E. (1979) J. Mol. Biol. 129, 411-431
3. Creighton, T. E. (1984) Methods Enzymol. 107, 305-329
4. Creighton, T. E. (1990) Biochem. J. 270, 1-16
5. Creighton, T. E. (1992) Science 256, 111-112
6. Creighton, T. E., and Goldenberg, D. P. (1984) J. Mol. Biol. 179, 497-526
7. Weissman, J. S., and Kim, P. S. (1991) Science 253, 1386-1393
8. Weissman, J. S., and Kim, P. S. (1992) Science 256, 112-114
9. Goldenberg, D. P. (1992) Trends Biochem. Sci. 17, 247-261
10. Chatrenet, B., and Chang, J.-Y. (1993) J. Biol. Chem. 268, 20988-20996
11. Chang, J.-Y., Canals, F., Schindler, P., Querol, E., and Aviles, F. X. (1994) J. Biol. Chem. 269, 22087-2094
12. Chang, J.-Y. (1996) Biochemistry 35, 11702-11709
13. Chang, J.-Y. (1994) Biochem. J. 300, 643-650
14. Chang, J.-Y., Schindler, P., Ramseier, U., and Lai, P. H. (1995) J. Biol. Chem. 270, 9207-9216
15. Wu, J., Yang, Y., and Watson, J. T. (1998) Protein Sci. 7, 1017-1028
16. Chang, J.-Y. (1995) J. Biol. Chem. 270, 25661-25666
17. Oas, T. G., and Kim, P. S. (1988) Nature 336, 42-48
18. van Mierlo, C. P. M., Darby, N. J., Neuhaus, D., and Creighton, T. E. (1991) J. Mol. Biol. 222, 373-390
19. Stanley, J. P., and Kim, P. S. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 1519-1523
20. Chang, J.-Y., Li, L., and Bulychev, A. (2000) J. Biol. Chem. 275, 8287-8289
21. van Mierlo, C. P. M., Darby, N. J., Neuhaus, D., and Creighton, T. E. (1991) J. Mol. Biol. 222, 353-371
22. Eigenbrot, C., Randal, M., and Kossiakoff, A. A. (1990) Protein Eng. 3, 591-598
23. Kress, L. F., and Laskowwski, M., Sr. (1967) J. Biol. Chem. 242, 4925-4929
24. Goldenberg, D. P., Bekeart, L. S., Laheru, D. A., and Zhou, J. D. (1993) Biochemistry 32, 2835-2844
25. Goldenberg, D. P. (1988) Biochemistry 27, 2481-2489