The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21CIP1/Waf1

Oncogene

Volumn 21, Issue 39, 2002, Pages 6123-6131

  Budram Mahadeo, Vishwanie ^a   Morris, Peter J ^a   Latchman, David S ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Apoptosis; Brn 3a; Cell cycle arrest; Neuronal cells; P53

Indexed keywords

PROTEIN BAX; PROTEIN P21; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR POU4F1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CELL CYCLE; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA-BINDING PROTEINS; FLOW CYTOMETRY; GENES, P53; HUMANS; LUCIFERASES; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSCRIPTION FACTOR BRN-3; TRANSCRIPTION FACTOR BRN-3A; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0037026606     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1205842     Document Type: Article

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