Acute alterations of glutamate, glutamine, GABA, and other amino acids after spinal cord contusion in rats

Neurochemical Research

Volumn 32, Issue 1, 2007, Pages 57-63

  Diaz Ruiz, Araceli ^a   Salgado Ceballos, Hermelinda ^b,c   Montes, Sergio ^a   Maldonado, Valente ^a   Tristan, Luis ^a   Alcaraz Zubeldia, Mireya ^a   Ríos, Camilo ^a  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^b HOSPITAL DE ESPECIALIDADES   (Mexico)

^c INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

Author keywords

Aspartate; Citrulline; GABA; Glutamate; Glutamine; Glycine; Spinal cord contusion; Taurine

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID; ASPARTIC ACID; CITRULLINE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; TAURINE;

AMINO ACID ANALYSIS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CONTUSION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LAMINECTOMY; NEUROCHEMISTRY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; TISSUE LEVEL;

ANIMALS; ASPARTIC ACID; CITRULLINE; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GLUTAMINE; GLYCINE; RATS; RATS, WISTAR; SPINAL CORD INJURIES; TAURINE;

ANIMALIA;

EID: 33845898469     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-006-9225-5     Document Type: Article

References (42)

1. Tei R, Kaido T, Nakase H, et al (2005) Secondary spinal cord hypoperfusion of circumscribed areas after injury in rats. Neurol Res 27:403-408
2. Hausmann ON (2003) Post-traumatic inflammation following spinal cord injury. Spinal Cord 41:369-378
3. Bethea JR, Dietrich WD (2002) Targeting the host inflammatory response in traumatic spinal cord injury. Curr Opin Neurol 15:355-360
4. Diaz-Ruiz A, Rios C, Duarte I, et al (1999) Cyclosporin-A inhibits lipid peroxidation after spinal cord injury in rats. Neurosci Lett 266:61-64
5. Ekshyyan O, Aw TY (2004) Apoptosis in acute and chronic neurological disorders. Front Biosci 9:1567-1576
6. Park E, Velumian AA, Fehlings MG (2004) The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration. J Neurotrauma 21:754-774
7. McAdoo DJ, Xu G, Robak G, et al (2000) Evidence that reversed glutamate uptake contributes significantly to glutamate release following experimental injury to the rat spinal cord. Brain Res 865:283-285
8. Kosenko E, Llansola M, Montoliu C, et al (2003) Glutamine synthetase activity and glutamine content in brain: modulation by NMDA receptors and nitric oxide. Neurochem Int 43:493-499
9. Danbolt NC (2001) Glutamate uptake. Prog Neurobiol 65:1-105
10. Agrawal SK, Fehlings MG (1997) Role of NMDA and non-NMDA ionotropic glutamate receptors in traumatic spinal cord axonal injury. J Neurosci 17:1055-1063
11. A neurotransmission and cerebral ischemia. J Neurochem 77:353-371
12. Tillakaratne NJ, Mouria M, Ziv NB, et al (2000) Increased expression of glutamate decarboxylase (GAD(67)) in feline lumbar spinal cord after complete thoracic spinal cord transection. J Neurosci Res 60:219-230
13. Gundersen RY, Vaagenes P, Breivik T, et al (2005) Glycine-an important neurotransmitter and cytoprotective agent. Acta Anaesthesiol Scand 49:1108-1116
14. Eulenburg V, Armsen W, Betz H, et al (2005) Glycine transporters: essential regulators of neurotransmission. Trenes Biochem Sci 30:325-333
15. Parsons CG, Danysz W, Hesselink M, et al (1998) Modulation of NMDA receptors by glycine-introduction to some basic aspects and recent developments. Amino Acids 14:207-216
16. Simpson RK Jr, Robertson CS, Goodman JC (1996) The role of glycine in spinal shock. J Spinal Cord Med 19:215-224
17. Schaffer S, Takahashi K, Azuma J (2000). Role of osmoregulation in the actions of taurine. Amino Acids 19:527-546
18. Tappaz ML (2004) Taurine biosynthetic enzymes and taurine transporter: molecular identification and regulations. Neurochem Res 29:83-96
19. Foos TM, Wu JY (2002) The role of taurine in the central nervous system and the modulation of intracellular calcium homeostasis. Neurochem Res 27:21-26
20. Stover JF, Unterberg AW (2000) Increased cerebrospinal fluid glutamate and taurine concentrations are associated with traumatic brain edema formation in rats. Brain Res 875:51-55
21. Smullin DH, Skilling SR, Larson AA (1990) Interactions between substance P, calcitonin gene-related peptide, taurine and excitatory amino acids in the spinal cord. Pain 42:93-101
22. Heneka MT, Feinstein DL (2001) Expression and function of inducible nitric oxide synthase in neurons. J Neuroimmunol 114:8-18
23. Xu J, Kim GM, Chen S (2001) iNOS and nitrotyrosine expression after spinal cord injury. J Neurotrauma 18:523-532
24. Diaz-Ruiz A, Ibarra A, Perez-Severiano F, et al (2002) Constitutive and inducible nitric oxide synthase activities after spinal cord contusion in rats, Neurosci Lett 319:129-132
25. Watanabe M, Fujimura Y, Nakamura M, et al (1998) Changes of amino acid levels and aspartate distribution in the cervical spinal cord after traumatic spinal cord injury. J Neurotrauma 15:285-293
26. Panter SS, Yum SW, Faden AI (1990) Alteration in extracellular amino acids after traumatic spinal cord injury. Ann Neurol 27:96-99
27. Demediuk P, Daly MP, Faden AI (1989) Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord. J Neurochem 52:1529-1536
28. Basso DM, Beattie MS, Bresnahan JC (1996) Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp Neurol 139:244-256
29. Perez-Neri I, Montes S, Boll MC, et al (2004) Liquid chromatographic- fluorimetric method for the estimation of nitric oxide biosynthesis in the central nervous system. J Chromatogr B Analyt Technol Biomed Life Sci 806:133-139
30. van der Hayden JA, Korf J (1978) Regional levels of GABA in the brain: semi-automated assay and prevention of post-morterm increase by 3-mercaptopropionic acid. J Neurochem 31:197-203
31. Perez-Neri, Castro E, Montes S, et al (2006) Arginine, Citrulline and nitrate concentration in the cerebrospinal fluid from acute hydrocephalus patients. J Chromatogr B (in press)
32. Mills CD, Xu GY, McAdoo DJ, et al (2001) Involvement of metabotropic glutamate receptors in excitatory amino acid and GABA release following spinal cord injury in rat. J Neurochem 79:835-848
33. Xu GY, Hughes MG, Ye Z (2004) Concentrations of glutamate released following spinal cord injury kill oligodendrocytes in the spinal cord. Exp Neurol 187:329-336
34. Patel AJ, Weir MD, Hunt A, et al (1985) Distribution of glutamine synthetase and glial fibrillary acidic protein and correlation of glutamine synthetase with glutamate decarboxylase in different regions of the rat central nervous system. Brain Res 331:1-9
35. Broer S, Brookes N (2001) Transfer of glutamine between astrocytes and neurons. J Neurochem 77:705-719
36. Laake JH, Slyngstad TA, Haug FM, et al (1995) Guamine from glial cells is essential for the maintenance of the nerve terminal pool of glutamate: immunogold evidence from hippocampal slice cultures. J Neurochem 65:871-881
37. Benton RL, Ross CD, Miller KE (2000) Glutamine synthetase activities in spinal white and gray matter 7 days following spinal cord injury in rats. Neurosci Lett 291:1-4
38. Profyris C, Cheema SS, Zang D, et al (2004) Degenerative and regenerative mechanisms governing spinal cord injury. Neurobiol Dis 15:415-436
39. Stys PK (1998) Anoxic and ischemic injury of myelinated axons in CNS white matter: from mechanistic concepts to therapeutics. J Cereb Blood Flow Metab 18:2-25
40. Ramonet D, Rodriguez MJ, Fredriksson K, et al (2004) In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death. Hippocampus 14:586-594
41. Rodriguez MJ, Robledo P, Andrade C, et al (2005) In vivo co-ordinated interactions between inhibitory systems to control glutamate-mediated hippocampal excitability. J Neurochem 95:651-661
42. Louzada PR, Lima AC, Mendonca-Silva DL, et al (2004) Taurine prevents the neurotoxicity of beta-amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other neurological disorders. FASEB J 18:511-518