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Volumn 63, Issue 1, 2007, Pages 43-50

Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients

Author keywords

CYP2E1; CYP3A4; Growth hormone; Hypersplenism; Oxidative stress; Thalassemia

Indexed keywords

6 HYDROXYCHLORZOXAZONE; 6BETA HYDROXYHYDROCORTISONE; ANTIOXIDANT; CARBONYL DERIVATIVE; CHLORZOXAZONE; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; GLUTATHIONE; GROWTH HORMONE; HEMOGLOBIN E; HYDROCORTISONE; IRON; LIPID; NITRIC OXIDE; OXIDIZING AGENT; PROTEIN;

EID: 33845879354     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-006-0224-x     Document Type: Article
Times cited : (19)

References (42)
  • 1
    • 0031755484 scopus 로고    scopus 로고
    • Clinical importance of non-genetic and genetic cytochrome P450 function tests in liver disease
    • Tanaka E (1998) Clinical importance of non-genetic and genetic cytochrome P450 function tests in liver disease. J Clin Pharm Ther 23:161-170
    • (1998) J Clin Pharm Ther , vol.23 , pp. 161-170
    • Tanaka, E.1
  • 2
    • 0029991247 scopus 로고    scopus 로고
    • Influence of clinicopathological variables on CYP protein expression in human liver
    • George J, Byth K, Farrell GC (1996) Influence of clinicopathological variables on CYP protein expression in human liver. J Gastroenterol Hepatol 11:33-39
    • (1996) J Gastroenterol Hepatol , vol.11 , pp. 33-39
    • George, J.1    Byth, K.2    Farrell, G.C.3
  • 3
    • 0041382561 scopus 로고    scopus 로고
    • Iron and CYP2E1-dependent oxidative stress and toxicity
    • Cederbaum AI (2003) Iron and CYP2E1-dependent oxidative stress and toxicity. Alcohol 30:115-120
    • (2003) Alcohol , vol.30 , pp. 115-120
    • Cederbaum, A.I.1
  • 5
    • 0034324594 scopus 로고    scopus 로고
    • Introduction to the problem of hemoglobin E-beta thalassemia
    • Weatherall DJ (2000) Introduction to the problem of hemoglobin E-beta thalassemia. J Pediatr Hematol Oncol 22:551
    • (2000) J Pediatr Hematol Oncol , vol.22 , pp. 551
    • Weatherall, D.J.1
  • 6
    • 0025060810 scopus 로고
    • Oxidative denaturation of red blood cells in thalassemia
    • Shinar E, Rachmilewitz EA (1990) Oxidative denaturation of red blood cells in thalassemia. Semin Hematol 27:70-82
    • (1990) Semin Hematol , vol.27 , pp. 70-82
    • Shinar, E.1    Rachmilewitz, E.A.2
  • 7
  • 10
    • 0033932447 scopus 로고    scopus 로고
    • Early onset of endocrine abnormalities in beta-thalassemia major in a developing country
    • Gulati R, Bhatia V, Agarwal SS (2000) Early onset of endocrine abnormalities in beta-thalassemia major in a developing country. J Pediatr Endocrinol Metab 13:651-656
    • (2000) J Pediatr Endocrinol Metab , vol.13 , pp. 651-656
    • Gulati, R.1    Bhatia, V.2    Agarwal, S.S.3
  • 11
    • 0024498663 scopus 로고
    • Effect of growth hormone therapy in growth hormone-deficient children on cytochrome P-450-dependent 3-N-demethylation of caffeine as measured by the caffeine 13CO2 breath test
    • Levitsky LL, Schoeller DA, Lambert GH, Edidin DV (1989) Effect of growth hormone therapy in growth hormone-deficient children on cytochrome P-450-dependent 3-N-demethylation of caffeine as measured by the caffeine 13CO2 breath test. Dev Pharmacol Ther 12:90-95
    • (1989) Dev Pharmacol Ther , vol.12 , pp. 90-95
    • Levitsky, L.L.1    Schoeller, D.A.2    Lambert, G.H.3    Edidin, D.V.4
  • 12
    • 8744269315 scopus 로고    scopus 로고
    • Effects of growth hormone deficiency and rhGH replacement therapy on the 6beta-hydroxycortisol/free cortisol ratio, a marker of CYP3A activity, in growth hormone-deficient children
    • Sinues B, Mayayo E, Fanlo A, Mayayo E Jr, Bernal ML, Bocos P, Bello E, Labarta JI, Ferrandez-Longas A (2004) Effects of growth hormone deficiency and rhGH replacement therapy on the 6beta-hydroxycortisol/free cortisol ratio, a marker of CYP3A activity, in growth hormone-deficient children. Eur J Clin Pharmacol 60: 559-564
    • (2004) Eur J Clin Pharmacol , vol.60 , pp. 559-564
    • Sinues, B.1    Mayayo, E.2    Fanlo, A.3    Mayayo Jr, E.4    Bernal, M.L.5    Bocos, P.6    Bello, E.7    Labarta, J.I.8    Ferrandez-Longas, A.9
  • 13
    • 0029020221 scopus 로고
    • Hormonal regulation of the zonated expression of cytochrome P-450 3A in rat liver
    • Oinonen T, Lindros KO (1995) Hormonal regulation of the zonated expression of cytochrome P-450 3A in rat liver. Biochem J 309:55-61
    • (1995) Biochem J , vol.309 , pp. 55-61
    • Oinonen, T.1    Lindros, K.O.2
  • 17
    • 0030588967 scopus 로고    scopus 로고
    • Determination of chlorzoxazone and 6-hydroxychlorzoxazone in human plasma and urine by high-performance liquid chromatography
    • Frye RF, Stiff DD (1996) Determination of chlorzoxazone and 6-hydroxychlorzoxazone in human plasma and urine by high-performance liquid chromatography. J Chromatogr B Biomed Appl 686:291-296
    • (1996) J Chromatogr B Biomed Appl , vol.686 , pp. 291-296
    • Frye, R.F.1    Stiff, D.D.2
  • 18
    • 0034284134 scopus 로고    scopus 로고
    • Liquid chromatographic determination of urinary 6beta-hydroxycortisol to assess cytochrome p-450 3A activity in HIV positive pregnant women
    • Homma M, Beckerman K, Hayashi S, Jayewardene AL, Oka K, Gambertoglio JG, Aweeka FT (2000) Liquid chromatographic determination of urinary 6beta-hydroxycortisol to assess cytochrome p-450 3A activity in HIV positive pregnant women. J Pharm Biomed Anal 23:629-635
    • (2000) J Pharm Biomed Anal , vol.23 , pp. 629-635
    • Homma, M.1    Beckerman, K.2    Hayashi, S.3    Jayewardene, A.L.4    Oka, K.5    Gambertoglio, J.G.6    Aweeka, F.T.7
  • 19
    • 0347361482 scopus 로고    scopus 로고
    • Urinary 6beta-hydroxycortisol: A validated test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and in animals
    • Galteau MM, Shamsa F (2003) Urinary 6beta-hydroxycortisol: a validated test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and in animals. Eur J Clin Pharmacol 59:713-733
    • (2003) Eur J Clin Pharmacol , vol.59 , pp. 713-733
    • Galteau, M.M.1    Shamsa, F.2
  • 20
    • 0027366166 scopus 로고
    • A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials
    • Draper HH, Squires EJ, Mahmoodi H, Wu J, Agarwal S, Hadley M (1993) A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials. Free Radic Biol Med 15:353-363
    • (1993) Free Radic Biol Med , vol.15 , pp. 353-363
    • Draper, H.H.1    Squires, E.J.2    Mahmoodi, H.3    Wu, J.4    Agarwal, S.5    Hadley, M.6
  • 21
    • 0028870104 scopus 로고
    • Sample pretreatment with nitrate reductase and glucose-6-phosphate dehydrogenase quantitatively reduces nitrate while avoiding interference by NADP+ when the Griess reaction is used to assay for nitrite
    • Verdon CP, Burton BA, Prior RL (1995) Sample pretreatment with nitrate reductase and glucose-6-phosphate dehydrogenase quantitatively reduces nitrate while avoiding interference by NADP+ when the Griess reaction is used to assay for nitrite. Anal Biochem 224:502-508
    • (1995) Anal Biochem , vol.224 , pp. 502-508
    • Verdon, C.P.1    Burton, B.A.2    Prior, R.L.3
  • 22
    • 0028239163 scopus 로고
    • Oxidative damage to proteins: Spectrophotometric method for carbonyl assay
    • Reznick AZ, Packer L (1994) Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol 233:357-363
    • (1994) Methods Enzymol , vol.233 , pp. 357-363
    • Reznick, A.Z.1    Packer, L.2
  • 23
    • 7644223129 scopus 로고    scopus 로고
    • Measurement of urinary hydrogen peroxide by FOX-1 method in conjunction with catalase in diabetes mellitus-a sensitive and specific approach
    • Banerjee D, Jacob J, Kunjamma G, Madhusoodanan UK, Ghosh S (2004) Measurement of urinary hydrogen peroxide by FOX-1 method in conjunction with catalase in diabetes mellitus-a sensitive and specific approach. Clin Chim Acta 350:233-236
    • (2004) Clin Chim Acta , vol.350 , pp. 233-236
    • Banerjee, D.1    Jacob, J.2    Kunjamma, G.3    Madhusoodanan, U.K.4    Ghosh, S.5
  • 25
    • 0014481378 scopus 로고
    • Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • Tietze F (1969) Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 27:502-522
    • (1969) Anal Biochem , vol.27 , pp. 502-522
    • Tietze, F.1
  • 26
    • 0031909513 scopus 로고    scopus 로고
    • Use of chlorzoxazone as an in vivo probe of cytochrome P450 2E1: Choice of dose and phenotypic trait measure
    • Frye RF, Adedoyin A, Mauro K, Matzke GR, Branch RA (1998) Use of chlorzoxazone as an in vivo probe of cytochrome P450 2E1: choice of dose and phenotypic trait measure. J Clin Pharmacol 38:82-89
    • (1998) J Clin Pharmacol , vol.38 , pp. 82-89
    • Frye, R.F.1    Adedoyin, A.2    Mauro, K.3    Matzke, G.R.4    Branch, R.A.5
  • 27
    • 0034092716 scopus 로고    scopus 로고
    • CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
    • Leclercq IA, Farrell GC, Field J, Bell DR, Gonzalez FJ, Robertson GR (2000) CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J Clin Invest 105:1067-1075
    • (2000) J Clin Invest , vol.105 , pp. 1067-1075
    • Leclercq, I.A.1    Farrell, G.C.2    Field, J.3    Bell, D.R.4    Gonzalez, F.J.5    Robertson, G.R.6
  • 28
    • 0035105069 scopus 로고    scopus 로고
    • Antioxidant defense status of red blood cells of patients with beta-thalassemia and Ebeta-thalassemia
    • Chakraborty D, Bhattacharyya M (2001) Antioxidant defense status of red blood cells of patients with beta-thalassemia and Ebeta-thalassemia. Clin Chim Acta 305:123-129
    • (2001) Clin Chim Acta , vol.305 , pp. 123-129
    • Chakraborty, D.1    Bhattacharyya, M.2
  • 30
    • 0030881997 scopus 로고    scopus 로고
    • Cytochrome P-450 2E1 in rat liver peroxisomes: Downregulation by ischemia/reperfusion-induced oxidative stress
    • Pahan K, Smith BT, Singh AK, Singh I (1997) Cytochrome P-450 2E1 in rat liver peroxisomes: downregulation by ischemia/reperfusion-induced oxidative stress. Free Radic Biol Med 23:963-971
    • (1997) Free Radic Biol Med , vol.23 , pp. 963-971
    • Pahan, K.1    Smith, B.T.2    Singh, A.K.3    Singh, I.4
  • 31
    • 0037371329 scopus 로고    scopus 로고
    • Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells
    • Hakkola J, Hu Y, Ingelman-Sundberg M (2003) Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells. J Pharmacol Exp Ther 304:1048-1054
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 1048-1054
    • Hakkola, J.1    Hu, Y.2    Ingelman-Sundberg, M.3
  • 32
    • 0030272970 scopus 로고    scopus 로고
    • Hepatotoxicity induced by iron overload and alcohol. Studies on the role of chelatable iron, cytochrome P450 2E1 and lipid peroxidation
    • Stal P, Johansson I, Ingelman-Sundberg M, Hagen K, Hultcrantz R (1996) Hepatotoxicity induced by iron overload and alcohol. Studies on the role of chelatable iron, cytochrome P450 2E1 and lipid peroxidation. J Hepatol 25:538-546
    • (1996) J Hepatol , vol.25 , pp. 538-546
    • Stal, P.1    Johansson, I.2    Ingelman-Sundberg, M.3    Hagen, K.4    Hultcrantz, R.5
  • 33
    • 0030935567 scopus 로고    scopus 로고
    • Cytochrome P-4502E1: Its physiological and pathological role
    • Lieber CS (1997) Cytochrome P-4502E1: its physiological and pathological role. Physiol Rev 77:517-544
    • (1997) Physiol Rev , vol.77 , pp. 517-544
    • Lieber, C.S.1
  • 35
    • 17844381008 scopus 로고    scopus 로고
    • Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: A comparison with nonalcoholics
    • Liangpunsakul S, Kolwankar D, Pinto A, Gorski JC, Hall SD, Chalasani N (2005) Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: a comparison with nonalcoholics. Hepatology 41:1144-1150
    • (2005) Hepatology , vol.41 , pp. 1144-1150
    • Liangpunsakul, S.1    Kolwankar, D.2    Pinto, A.3    Gorski, J.C.4    Hall, S.D.5    Chalasani, N.6
  • 36
    • 0028100766 scopus 로고
    • The effect of splenomegaly on splanchnic hemodynamics in nonalcoholic cirrhosis after distal splenorenal shunt and splenopancreatic disconnection
    • Takagi K, Ashida H, Utsunomiya J (1994) The effect of splenomegaly on splanchnic hemodynamics in nonalcoholic cirrhosis after distal splenorenal shunt and splenopancreatic disconnection. Hepatology 20:342-348
    • (1994) Hepatology , vol.20 , pp. 342-348
    • Takagi, K.1    Ashida, H.2    Utsunomiya, J.3
  • 37
    • 0035068588 scopus 로고    scopus 로고
    • Bioavailability of oral hydrocortisone in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
    • Charmandari E, Johnston A, Brook CG, Hindmarsh PC (2001) Bioavailability of oral hydrocortisone in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. J Endocrinol 169:65-70
    • (2001) J Endocrinol , vol.169 , pp. 65-70
    • Charmandari, E.1    Johnston, A.2    Brook, C.G.3    Hindmarsh, P.C.4
  • 39
    • 0019275913 scopus 로고
    • Effect of growth hormone on human drug metabolism: Time course and substrate specificity
    • Redmond GP, Bell JJ, Nichola PS, Perel JM (1980) Effect of growth hormone on human drug metabolism: time course and substrate specificity. Pediatr Pharmacol (New York) 1:63-70
    • (1980) Pediatr Pharmacol (New York) , vol.1 , pp. 63-70
    • Redmond, G.P.1    Bell, J.J.2    Nichola, P.S.3    Perel, J.M.4
  • 40
    • 29244466095 scopus 로고    scopus 로고
    • Sexually dimorphic regulation of hepatic isoforms of human cytochrome p450 by growth hormone
    • Dhir RN, Dworakowski W, Thangavel C, Shapiro BH (2006) Sexually dimorphic regulation of hepatic isoforms of human cytochrome p450 by growth hormone. J Pharmacol Exp Ther 316:87-94
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 87-94
    • Dhir, R.N.1    Dworakowski, W.2    Thangavel, C.3    Shapiro, B.H.4
  • 41
    • 1942423663 scopus 로고    scopus 로고
    • Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xantine oxidase in healthy males and females
    • Wenk M, Todesco L, Krahenbuhl S (2004) Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xantine oxidase in healthy males and females. Br J Clin Pharmacol 57:495-499
    • (2004) Br J Clin Pharmacol , vol.57 , pp. 495-499
    • Wenk, M.1    Todesco, L.2    Krahenbuhl, S.3
  • 42
    • 0028071759 scopus 로고
    • Noninvasive tests of CYP3A enzymes
    • Watkins PB (1994) Noninvasive tests of CYP3A enzymes. Pharmacogenetics 4:171-184
    • (1994) Pharmacogenetics , vol.4 , pp. 171-184
    • Watkins, P.B.1


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