Liquid chromatographic determination of urinary 6β-hydroxycortisol to assess cytochrome p-450 3A activity in HIV positive pregnant women

Journal of Pharmaceutical and Biomedical Analysis

Volumn 23, Issue 4, 2000, Pages 629-635

  Homma, Masato ^a,d   Beckerman, Karen ^b   Hayashi, Sandra ^c   Jayewardene, Anura L ^c   Oka, Kitaro ^a   Gambertoglio, John G ^c   Aweeka, Francesca T ^c  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

CYP3A; High performance liquid chromatography; Highly active anti retroviral therapy; HIV positive pregnant women; Urinary 6 hydroxycortisol

Indexed keywords

6BETA HYDROXYHYDROCORTISONE; ABACAVIR; ANTIRETROVIRUS AGENT; CYTOCHROME P450 3A; HYDROCORTISONE; INDINAVIR; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; ZIDOVUDINE;

ARTICLE; CLINICAL ARTICLE; DRUG METABOLISM; DRUG MONITORING; ENZYME ACTIVITY; ENZYME POLYMORPHISM; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PREGNANCY COMPLICATION; PRIORITY JOURNAL; URINALYSIS;

ADULT; ANTI-HIV AGENTS; ARYL HYDROCARBON HYDROXYLASES; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HIV SEROPOSITIVITY; HUMANS; HYDROCORTISONE; OXIDOREDUCTASES, N-DEMETHYLATING; PREGNANCY;

EID: 0034284134     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(00)00334-4     Document Type: Article

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