Activation of the Fanconi anemia/BRCA pathway and recombination repair in the cellular response to solar ultraviolet light

Cancer Research

Volumn 66, Issue 23, 2006, Pages 11140-11147

  Dunn, Jessica ^a   Potter, Marisa ^a   Rees, Adam ^a   Rünger, Thomas M ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; DNA; FANCONI ANEMIA GROUP D2 PROTEIN; FANCONI ANEMIA PROTEIN; RAD51 PROTEIN;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL DIVISION; CELL REGENERATION; DNA CROSS LINKING; DNA DAMAGE; DNA SYNTHESIS; FANCONI ANEMIA; HUMAN; HUMAN CELL; IONIZING RADIATION; MITOSIS; PRIORITY JOURNAL; RADIATION RESPONSE; SIGNAL TRANSDUCTION; SKIN CELL; SKIN FIBROBLAST; UBIQUITINATION; ULTRAVIOLET RADIATION;

BRCA1 PROTEIN; CELL CYCLE; CELL NUCLEUS; CELLS, CULTURED; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; FIBROBLASTS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFANT, NEWBORN; MALE; RAD51 RECOMBINASE; RECOMBINATION, GENETIC; SIGNAL TRANSDUCTION; TIME FACTORS; ULTRAVIOLET RAYS;

EID: 33845765683     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-0563     Document Type: Article

References (50)

1. Auerbach AD. Fanconi anemia. Dermatol Clin 1995;13:41-9.
2. Kutler DI, Singh B, Satagopan J, et al. A 20-year perspective on the International Fanconi Anemia Registry (IFAR). Blood 2003;101:1249-56.
3. Bogliolo M, Cabre O, Callen E, et al. The Fanconi anaemia genome stability and tumour suppressor network. Mutagenesis 2002;17:529-38.
4. Rosenberg PS, Greene MH, Alter BP. Cancer incidence in persons with Fanconi anemia. Blood 2003;101:822-6.
5. Alter BP. Cancer in Fanconi anemia, 1927-2001. Cancer 2003;97:425-40.
6. Alter BP, Greene MH, Velazquez I, Rosenberg PS. Cancer in Fanconi anemia. Blood 2003;101:2072.
7. Joenje H, Patel KJ. The emerging genetic and molecular basis of Fanconi anemia. Nat Rev Genet 2001;2:446-57.
8. Taniguchi T, Garcia-Higuera I, Xu B, et al. Convergence of the Fanconi anemia and ataxia telangiectasia signaling pathways. Cell 2002;109:459-72.
9. Cabuy E, Newton C, Joksic G, et al. Accelerated telomere shortening and telomere abnormalities in radiosensitive cell lines. Radiat Res 2005;164:53-62.
10. Gregory RC, Taniguchi T, D'Andrea AD. Regulation of the Fanconi anemia pathway by monoubiquitination. Semin Cancer Biol 2003;13:77-82.
11. Garcia-Higuera I, Taniguchi T, Ganesan S, et al. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell 2001;7:249-62.
12. Meetei AR, de Winter JP, Medhurst AL, et al. A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet 2003;35:165-70.
13. D'Andrea AD, Grompe M. The Fanconi anemia/BRCA pathway. Nat Rev Cancer 2003;3:23-34.
14. Friedberg EC, Walker GC, Siede W, Wood BD, Schultz RA, Ellenberger T. DNA repair and mutagenesis. 2nd ed. Washington (DC): ASM Press; 2006.
15. Nakanishi K, Yang YG, Pierce AJ, et al. Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proc Natl Acad Sci U S A 2005;102:1110-5.
16. Thompson LH, Hinz JM, Yamada NA, Jones NJ. How Fanconi anemia proteins promote the four Rs: replication, recombination, repair, and recovery. Environ Mol Mutagen 2005;45:128-42.
17. Rünger TM. Ultraviolet light. In: Bolognia JL, Jorizzo JL, Rapini RP, editors. Dermatology. London: Mosby; 2003. p. 1353-63.
18. Kielbassa C, Roza L, Epe B. Wavelength dependence of oxidative DNA damage induced by UV and visible light. Carcinogenesis 1997;18:811-6.
19. DNA damage by radiation. In: Friedberg EC, Walker GC, Siede W, Wood RD, Schultz RA, Ellenberger T, editors. DNA repair and mutagenesis. 2nd ed. Washington (DC): ASM Press; 2006. p. 25-35.
20. Pichierri P, Franchitto A, Rosselli F. BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks. EMBO J 2004;23:3154-63.
21. Hill MA. Radiation damage to DNA: the importance of track structure. Radiat Meas 1999;31:15-23.
22. Decraene D, Agostinis P, Pupe A, de Haes P, Garmyn M. Acute response of human skin to solar radiation: regulation and function of the p53 protein. J Photochem Photobiol B 2001;63:78-83.
23. Smith ML, Seo YR. p53 regulation of DNA excision repair pathways. Mutagenesis 2002;17:149-56.
24. Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-31.
25. Finlay CA. p53 loss of function: implications for the processes of immortalization and tumorigenesis. Bioessays 1992;14:557-60.
26. Tiemann F, Deppert W. Stabilization of the tumor suppressor p53 during cellular transformation by simian virus 40: influence of viral and cellular factors and biological consequences. J Virol 1994;68:2869-78.
27. Stanulis-Praeger BM, Gilchrest BA. Effect of donor age and prior sun exposure on growth inhibition of cultured human dermal fibroblasts by all trans-retinoic acid. J Cell Physiol 1989;139:116-24.
28. Werninghaus K, Handjani RM, Gilchrest BA. Protective effect of α-tocopherol in carrier liposomes on ultraviolet-mediated human epidermal cell damage in vitro. Photodermatol Photoimmunol Photomed 1991;8:236-42.
29. Kappes UP, Luo D, Potter M, Schulmeister K, Rünger TM. Short- and long-wave ultraviolet light (UVB and UVA) induce similar mutations in human skin cells. J Invest Dermatol 2006;126:667-75.
30. Wojewodzka M, Buraczewska I, Kruszewski M. A modified neutral comet assay: elimination of lysis at high temperature and validation of the assay with anti-single-stranded DNA antibody. Mutat Res 2002;518:9-20.
31. Rothfuss A, Grompe M. Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway. Mol Cell Biol 2004;24:123-34.
32. Mi J, Kupfer GM. The Fanconi anemia core complex associates with chromatin during S phase. Blood 2005;105:759-66.
33. Taniguchi T, Garcia-Higuera I, Andreassen PR, Gregory RC, Grompe M, D'Andrea AD. S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood 2002;100:2414-20.
34. Kalb R, Duerr M, Wagner M, et al. Lack of sensitivity of primary Fanconi's anemia fibroblasts to UV and ionizing radiation. Radiat Res 2004;161:318-25.
35. Nijman SM, Huang TT, Dirac AM, et al. The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol Cell 2005;17:331-9.
36. Thiriet C, Hayes JJ. Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair. Mol Cell 2005;18:617-22.
37. Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998;273:5858-68.
38. Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 1999;146:905-16.
39. Rothkamp K, Löbrich M. Evidence for a lack of DNA double-strand break repair in human cells exposed to very low X-ray doses. Proc Natl Acad Sci U S A 2002;100:5057-62.
40. Ichijima Y, Sakasai R, Okita N, Asahina H, Mizutani S, Teraoka H. Phosphorylation of histone H2AX at M phase in human cells without DNA damage response. Biochem Biophys Res Commun 2005;336:807-12.
41. Helleday T. Pathways for mitotic homologous recombination in mammalian cells. Mutat Res 2003;532:103-15.
42. Osborn AJ, Elledge SJ, Zou L. Checking on the fork: the DNA-replication stress-response pathway. Trends Cell Biol 2002;12:509-16.
43. Howlett NG, Taniguchi T, Durkin SG, D'Andrea AD, Glover TW. The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability. Hum Mol Genet 2005;14:693-701.
44. Lomonosov M, Anand S, Sangrithi M, Davies R, Venkitaraman AR. Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein. Genes Dev 2003;17:3017-22.
45. Holmquist GP, Maher VM. The bypass of DNA lesions by DNA and RNA polymerases. Mutat Res 2002;510:1-7.
46. Masutani C, Kusumoto R, Yamada A, et al. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta. Nature 1999;399:700-4.
47. Johnson RE, Kondratick CM, Prakash S, Prakash L. hRAD30 mutations in the variant form of xeroderma pigmentosum. Science 1999;285:263-5.
48. Thakur M, Wernick M, Collins C, Limoli CL, Crowley E, Cleaver JE. DNA polymerase eta undergoes alternative splicing, protects against UV sensitivity and apoptosis, and suppresses Mre11-dependent recombination. Genes Chromosomes Cancer 2001;32:222-35.
49. Cleaver JE, Laposa RR, Limoli CL. DNA replication in the face of (In)surmountable odds. Cell Cycle 2003;2:310-5.
50. Limoli CL, Giedzinski E, Bonner WM, Cleaver JE. UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, γ-H2AX formation, and Mre11 relocalization. Proc Natl Acad Sci U S A 2002;99:233-8.