Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD

Circulation

Volumn 114, Issue 24, 2006, Pages 2584-2594

  Remme, Carol Ann ^a,d   Verkerk, Arie O ^a   Nuyens, Dieter ^b   Van Ginneken, Antoni C G ^a   Van Brunschot, Sandra ^a   Belterman, Charly N W ^a   Wilders, Ronald ^a   Van Roon, Marian A ^a   Tan, Hanno L ^a   Wilde, Arthur A M ^a   Carmeliet, Peter ^b   De Bakker, Jacques M T ^a,c   Veldkamp, Marieke W ^a   Bezzina, Connie R ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Conduction; Death, sudden; Electrophysiology; Genetics; Ion channels; Long QT syndrome; Sodium

Indexed keywords

FLECAINIDE; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRADYCARDIA; CARDIAC SODIUM CHANNEL DISEASE; CONTROLLED STUDY; ELECTROCARDIOGRAPHY; ELECTRODE; EPICARDIUM MAPPING; GENE MUTATION; HEART DISEASE; HEART ELECTROPHYSIOLOGY; HEART RATE; HEART RIGHT VENTRICLE; HEART VENTRICLE CONDUCTION; HETEROZYGOSITY; ISOLATED HEART; MOUSE; NONHUMAN; PATCH CLAMP; PHENOTYPE; PRIORITY JOURNAL; QRS COMPLEX; QT PROLONGATION; SINUS ARREST; SINUS BRADYCARDIA; SODIUM CURRENT; STATISTICAL SIGNIFICANCE; TELEMETRY; TRANSGENIC MOUSE; WILD TYPE;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIA; BODY SURFACE POTENTIAL MAPPING; BRADYCARDIA; ELECTROCARDIOGRAPHY; LONG QT SYNDROME; MICE; MUTATION; MYOCYTES, CARDIAC; PHENOTYPE; RNA, MESSENGER; SODIUM CHANNELS; SYNDROME;

EID: 33845708766     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.106.653949     Document Type: Article

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