메뉴 건너뛰기




Volumn 120, Issue 1, 2007, Pages 90-102

Mature dendritic cells pulsed with exosomes stimulate efficient cytotoxic T-lymphocyte responses and antitumour immunity

Author keywords

Antitumour immunity; Cytotoxic T lymphocyte; Dendritic cell; Exosome; Vaccine

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CYTOTOXICITY; DENDRITIC CELL; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; T LYMPHOCYTE; TUMOR IMMUNITY;

EID: 33845677330     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2006.02483.x     Document Type: Article
Times cited : (204)

References (46)
  • 1
    • 0141707939 scopus 로고    scopus 로고
    • ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells
    • Guermonprez P, Saveanu L, Kleijmeer M, Davoust J, Van Endert P, Amigorena S. ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature 2003; 425 (6956):397-402.
    • (2003) Nature , vol.425 , Issue.6956 , pp. 397-402
    • Guermonprez, P.1    Saveanu, L.2    Kleijmeer, M.3    Davoust, J.4    Van Endert, P.5    Amigorena, S.6
  • 2
    • 0035109189 scopus 로고    scopus 로고
    • Antigen loading of MHC class I molecules in the endocytic tract
    • Kleijmeer MJ, Escola JM, UytdeHaag FG et al. Antigen loading of MHC class I molecules in the endocytic tract. Traffic 2001; 2:124-37.
    • (2001) Traffic , vol.2 , pp. 124-137
    • Kleijmeer, M.J.1    Escola, J.M.2    UytdeHaag, F.G.3
  • 4
    • 0031863853 scopus 로고    scopus 로고
    • Eradication of established murine tumors using a novel cell-free vaccine: Dendritic cell-derived exosomes
    • Zitvogel L, Regnault A, Lozier A et al. Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes. Nat Med 1998; 4:594-600.
    • (1998) Nat Med , vol.4 , pp. 594-600
    • Zitvogel, L.1    Regnault, A.2    Lozier, A.3
  • 5
    • 0033767690 scopus 로고    scopus 로고
    • Exosome: From internal vesicle of the multivesicular body to intercellular signaling device
    • Denzer K, Kleijmeer MJ, Heijnen HF, Stoorvogel W, Geuze HJ. Exosome: from internal vesicle of the multivesicular body to intercellular signaling device. J Cell Sci 2000; 113:3365-74.
    • (2000) J Cell Sci , vol.113 , pp. 3365-3374
    • Denzer, K.1    Kleijmeer, M.J.2    Heijnen, H.F.3    Stoorvogel, W.4    Geuze, H.J.5
  • 6
    • 0032493658 scopus 로고    scopus 로고
    • Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes
    • Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze HJ. Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. J Biol Chem 1998; 273 (32):20121-7.
    • (1998) J Biol Chem , vol.273 , Issue.32 , pp. 20121-20127
    • Escola, J.M.1    Kleijmeer, M.J.2    Stoorvogel, W.3    Griffith, J.M.4    Yoshie, O.5    Geuze, H.J.6
  • 7
    • 0035166047 scopus 로고    scopus 로고
    • Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry
    • Clayton A, Court J, Navabi H, Adams M, Mason MD, Hobot JA, Newman GR, Jasani B. Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry. J Immunol Meth 2001; 247 (1-2):163-74.
    • (2001) J Immunol Meth , vol.247 , Issue.1-2 , pp. 163-174
    • Clayton, A.1    Court, J.2    Navabi, H.3    Adams, M.4    Mason, M.D.5    Hobot, J.A.6    Newman, G.R.7    Jasani, B.8
  • 9
    • 0037141153 scopus 로고    scopus 로고
    • Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles
    • Andreola G, Rivoltini L, Castelli C et al. Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J Exp Med 2002; 195:1303-16.
    • (2002) J Exp Med , vol.195 , pp. 1303-1316
    • Andreola, G.1    Rivoltini, L.2    Castelli, C.3
  • 10
    • 3042593903 scopus 로고    scopus 로고
    • Exosomes from plasmacytoma cells as a tumor vaccine
    • Altieri SL, Khan AN, Tomasi TB. Exosomes from plasmacytoma cells as a tumor vaccine. J Immunother 2004; 27:282-8.
    • (2004) J Immunother , vol.27 , pp. 282-288
    • Altieri, S.L.1    Khan, A.N.2    Tomasi, T.B.3
  • 11
    • 20244373139 scopus 로고    scopus 로고
    • Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming
    • Wolfers J, Lozier A, Raposo G et al. Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat Med 2001; 7:297-303.
    • (2001) Nat Med , vol.7 , pp. 297-303
    • Wolfers, J.1    Lozier, A.2    Raposo, G.3
  • 12
    • 0037183242 scopus 로고    scopus 로고
    • Malignant effusions and immunogenic tumour-derived exosomes
    • Andre F, Schartz NE, Movassagh M et al. Malignant effusions and immunogenic tumour-derived exosomes. Lancet 2002; 360 (9329):295-305.
    • (2002) Lancet , vol.360 , Issue.9329 , pp. 295-305
    • Andre, F.1    Schartz, N.E.2    Movassagh, M.3
  • 14
    • 10744229153 scopus 로고    scopus 로고
    • Exosomes as potent cellfree peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells
    • Andre F, Chaput N, Schartz NE et al. Exosomes as potent cellfree peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells. J Immunol 2004; 172:2126-36.
    • (2004) J Immunol , vol.172 , pp. 2126-2136
    • Andre, F.1    Chaput, N.2    Schartz, N.E.3
  • 15
    • 10744220836 scopus 로고    scopus 로고
    • Exosomes as potent cell-free peptide-based vaccine. II. Exosomes in CpG adjuvants efficiently prime naive Tc1 lymphocytes leading to tumor rejection
    • Chaput N, Schartz NE, Andre F et al. Exosomes as potent cell-free peptide-based vaccine. II. Exosomes in CpG adjuvants efficiently prime naive Tc1 lymphocytes leading to tumor rejection. J Immunol 2004; 172:2137-46.
    • (2004) J Immunol , vol.172 , pp. 2137-2146
    • Chaput, N.1    Schartz, N.E.2    Andre, F.3
  • 16
    • 14844325736 scopus 로고    scopus 로고
    • Exosomes: A new delivery system for tumor antigens in cancer immunotherapy
    • Cho JA, Yeo DJ, Son HY et al. Exosomes: a new delivery system for tumor antigens in cancer immunotherapy. Int J Cancer 2005; 114:613-22.
    • (2005) Int J Cancer , vol.114 , pp. 613-622
    • Cho, J.A.1    Yeo, D.J.2    Son, H.Y.3
  • 17
    • 18144372419 scopus 로고    scopus 로고
    • Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: Results of the first phase I clinical trial
    • Escudier B, Dorval T, Chaput N et al. Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of the first phase I clinical trial. J Transl Med 2005; 3:10.
    • (2005) J Transl Med , vol.3 , pp. 10
    • Escudier, B.1    Dorval, T.2    Chaput, N.3
  • 18
    • 18144369346 scopus 로고    scopus 로고
    • A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer
    • Morse MA, Garst J, Osada T et al. A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer. J Transl Med 2005; 3:9.
    • (2005) J Transl Med , vol.3 , pp. 9
    • Morse, M.A.1    Garst, J.2    Osada, T.3
  • 19
    • 0036906477 scopus 로고    scopus 로고
    • Indirect activation of naive CD4+ T cells by dendritic cell-derived exosomes
    • Thery C, Duban L, Segura E, Veron P, Lantz O, Amigorena S. Indirect activation of naive CD4+ T cells by dendritic cell-derived exosomes. Nat Immunol 2002; 3:1156-62.
    • (2002) Nat Immunol , vol.3 , pp. 1156-1162
    • Thery, C.1    Duban, L.2    Segura, E.3    Veron, P.4    Lantz, O.5    Amigorena, S.6
  • 21
    • 0035950970 scopus 로고    scopus 로고
    • DNA array and biological characterization of the impact of the maturation status of mouse dendritic cells on their phenotype and antitumor vaccination efficacy
    • Chen Z, Dehm S, Bonham K, Kamencic H, Juurlink B, Zhang X, Gordon JR, Xiang J. DNA array and biological characterization of the impact of the maturation status of mouse dendritic cells on their phenotype and antitumor vaccination efficacy. Cell Immunol 2001; 214:60-71.
    • (2001) Cell Immunol , vol.214 , pp. 60-71
    • Chen, Z.1    Dehm, S.2    Bonham, K.3    Kamencic, H.4    Juurlink, B.5    Zhang, X.6    Gordon, J.R.7    Xiang, J.8
  • 22
    • 2942516628 scopus 로고    scopus 로고
    • Modulating vaccine responses with dendritic cells and Toll-like receptors
    • Pulendran B. Modulating vaccine responses with dendritic cells and Toll-like receptors. Immunol Rev 2004; 199:227-50.
    • (2004) Immunol Rev , vol.199 , pp. 227-250
    • Pulendran, B.1
  • 23
    • 10344242384 scopus 로고    scopus 로고
    • Tumor antigens and tumor vaccines: Peptides as immunogens
    • Slingluff CL Jr. Tumor antigens and tumor vaccines: peptides as immunogens. Semin Surg Oncol 1996; 12:446-53.
    • (1996) Semin Surg Oncol , vol.12 , pp. 446-453
    • Slingluff Jr., C.L.1
  • 25
    • 0037323941 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha (TNF-alpha) transgene-expressing dendritic cells (DCs) undergo augmented cellular maturation and induce more robust T-cell activation and antitumour immunity than DCs generated in recombinant TNF-alpha
    • Zhang W, Chen Z, Li F, Kamencic H, Juurlink B, Gordon JR, Xiang J. Tumour necrosis factor-alpha (TNF-alpha) transgene-expressing dendritic cells (DCs) undergo augmented cellular maturation and induce more robust T-cell activation and antitumour immunity than DCs generated in recombinant TNF-alpha. Immunology 2003; 108:177-88.
    • (2003) Immunology , vol.108 , pp. 177-188
    • Zhang, W.1    Chen, Z.2    Li, F.3    Kamencic, H.4    Juurlink, B.5    Gordon, J.R.6    Xiang, J.7
  • 26
    • 0030849769 scopus 로고    scopus 로고
    • Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody
    • Porgador A, Yewdell JW, Deng Y, Bennink JR, Germain RN. Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity 1997; 6:715-26.
    • (1997) Immunity , vol.6 , pp. 715-726
    • Porgador, A.1    Yewdell, J.W.2    Deng, Y.3    Bennink, J.R.4    Germain, R.N.5
  • 27
    • 20444362068 scopus 로고    scopus 로고
    • A new dynamic model of CD8+ T effector cell responses via CD4+ T helper antigen-presenting cells
    • Xiang J, Huang H, Liu Y. A new dynamic model of CD8+ T effector cell responses via CD4+ T helper antigen-presenting cells. J Immunol 2005; 174:7497-505.
    • (2005) J Immunol , vol.174 , pp. 7497-7505
    • Xiang, J.1    Huang, H.2    Liu, Y.3
  • 28
    • 0028262128 scopus 로고
    • Determination of lymphocyte division by flow cytometry
    • Lyons AB, Parish CR. Determination of lymphocyte division by flow cytometry. J Immunol Meth 1994; 171:131-7.
    • (1994) J Immunol Meth , vol.171 , pp. 131-137
    • Lyons, A.B.1    Parish, C.R.2
  • 29
    • 12744278406 scopus 로고    scopus 로고
    • Enhanced antitumor immunity derived from a novel vaccine of fusion hybrid between dendritic and engineered myeloma cells
    • Hao S, Bi X, Xu S, Wei Y, Wu X, Guo X, Carlsen S, Xiang J. Enhanced antitumor immunity derived from a novel vaccine of fusion hybrid between dendritic and engineered myeloma cells. Exp Oncol 2004; 26:300-6.
    • (2004) Exp Oncol , vol.26 , pp. 300-306
    • Hao, S.1    Bi, X.2    Xu, S.3    Wei, Y.4    Wu, X.5    Guo, X.6    Carlsen, S.7    Xiang, J.8
  • 30
    • 14744268594 scopus 로고    scopus 로고
    • Boosting vaccinations with peptide-pulsed CD34+ progenitor-derived dendritic cells can expand long-lived melanoma peptide-specific CD8+ T cells in patients with metastatic melanoma
    • Palucka AK, Dhodapkar MV, Paczesny S, Ueno H, Fay J, Banchereau J. Boosting vaccinations with peptide-pulsed CD34+ progenitor-derived dendritic cells can expand long-lived melanoma peptide-specific CD8+ T cells in patients with metastatic melanoma. J Immunother 2005; 28:158-68.
    • (2005) J Immunother , vol.28 , pp. 158-168
    • Palucka, A.K.1    Dhodapkar, M.V.2    Paczesny, S.3    Ueno, H.4    Fay, J.5    Banchereau, J.6
  • 31
    • 0032860314 scopus 로고    scopus 로고
    • C-type lectin-like domains
    • Drickamer K. C-type lectin-like domains. Curr Opin Struct Biol 1999; 9:585-90.
    • (1999) Curr Opin Struct Biol , vol.9 , pp. 585-590
    • Drickamer, K.1
  • 32
    • 0038312168 scopus 로고    scopus 로고
    • Direct stimulation of naive T cells by membrane vesicles from antigen-presenting cells: Distinct roles for CD54 and B7 molecules
    • Hwang I, Shen X, Sprent J. Direct stimulation of naive T cells by membrane vesicles from antigen-presenting cells: distinct roles for CD54 and B7 molecules. Proc Natl Acad Sci USA 2003; 100:6670-5.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 6670-6675
    • Hwang, I.1    Shen, X.2    Sprent, J.3
  • 33
    • 0346366993 scopus 로고    scopus 로고
    • Cutting edge: CD4+ T cell help can be essential for primary CD8+ T cell responses in vivo
    • Wang JC, Livingstone AM. Cutting edge: CD4+ T cell help can be essential for primary CD8+ T cell responses in vivo. J Immunol 2003; 171 (12):6339-43.
    • (2003) J Immunol , vol.171 , Issue.12 , pp. 6339-6343
    • Wang, J.C.1    Livingstone, A.M.2
  • 34
    • 1542619336 scopus 로고    scopus 로고
    • Memory T cells originate from adoptively transferred effectors and reconstituting host cells after sequential lymphodepletion and adoptive immunotherapy
    • Wang LX, Kjaergaard J, Cohen PA, Shu S, Plautz GE. Memory T cells originate from adoptively transferred effectors and reconstituting host cells after sequential lymphodepletion and adoptive immunotherapy. J Immunol 2004; 172:3462-8.
    • (2004) J Immunol , vol.172 , pp. 3462-3468
    • Wang, L.X.1    Kjaergaard, J.2    Cohen, P.A.3    Shu, S.4    Plautz, G.E.5
  • 36
    • 24644485206 scopus 로고    scopus 로고
    • Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses
    • Segura E, Amigorena S, Thery C. Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses. Blood Cell Mol Dis 2005; 35:89-93.
    • (2005) Blood Cell Mol Dis , vol.35 , pp. 89-93
    • Segura, E.1    Amigorena, S.2    Thery, C.3
  • 37
  • 38
    • 24644524982 scopus 로고    scopus 로고
    • The immunogenicity of dendritic cell-derived exosomes
    • Quah BJ, O'Neill HC. The immunogenicity of dendritic cell-derived exosomes. Blood Cell Mol Dis 2005; 35:94-110.
    • (2005) Blood Cell Mol Dis , vol.35 , pp. 94-110
    • Quah, B.J.1    O'Neill, H.C.2
  • 39
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001; 2:675-80.
    • (2001) Nat Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 40
    • 0031922605 scopus 로고    scopus 로고
    • Transfer of antigen between dendritic cells in the stimulation of primary T cell proliferation
    • Knight SC, Iqball S, Roberts MS, Macatonia S, Bedford PA. Transfer of antigen between dendritic cells in the stimulation of primary T cell proliferation. Eur J Immunol 1998; 28:1636-44.
    • (1998) Eur J Immunol , vol.28 , pp. 1636-1644
    • Knight, S.C.1    Iqball, S.2    Roberts, M.S.3    Macatonia, S.4    Bedford, P.A.5
  • 41
    • 0037331548 scopus 로고    scopus 로고
    • The C-type lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells
    • Cambi A, Gijzen K, de Vries JM et al. The C-type lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells. Eur J Immunol 2003; 33:532-8.
    • (2003) Eur J Immunol , vol.33 , pp. 532-538
    • Cambi, A.1    Gijzen, K.2    De Vries, J.M.3
  • 43
    • 0034735552 scopus 로고    scopus 로고
    • The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments
    • Mahnke K, Guo M, Lee S, Sepulveda H, Swain SL, Nussenzweig M, Steinman RM. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J Cell Biol 2000; 151:673-84.
    • (2000) J Cell Biol , vol.151 , pp. 673-684
    • Mahnke, K.1    Guo, M.2    Lee, S.3    Sepulveda, H.4    Swain, S.L.5    Nussenzweig, M.6    Steinman, R.M.7
  • 44
    • 1942446664 scopus 로고    scopus 로고
    • Proteomic analysis of exosomes isolated from human malignant pleural effusions
    • Bard MP, Hegmans JP, Hemmes A et al. Proteomic analysis of exosomes isolated from human malignant pleural effusions. Am J Respir Cell Mol Biol 2004; 31:114-21.
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 114-121
    • Bard, M.P.1    Hegmans, J.P.2    Hemmes, A.3
  • 45
    • 0343953049 scopus 로고    scopus 로고
    • Combinational immunotherapy for established tumors with engineered tumor vaccines and adenovirus-mediated gene transfer
    • Xiang J, Chen Y, Moyana T. Combinational immunotherapy for established tumors with engineered tumor vaccines and adenovirus-mediated gene transfer. Cancer Gene Ther 2000; 7:1023-33.
    • (2000) Cancer Gene Ther , vol.7 , pp. 1023-1033
    • Xiang, J.1    Chen, Y.2    Moyana, T.3
  • 46
    • 3042609926 scopus 로고    scopus 로고
    • Dendritic cells engineered to express the Flt3 ligand stimulate type I immune response, and induce enhanced cytoxic T and natural killer cell cytotoxicities and antitumor immunity
    • Liu Y, Huang H, Chen Z, Zong L, Xiang J. Dendritic cells engineered to express the Flt3 ligand stimulate type I immune response, and induce enhanced cytoxic T and natural killer cell cytotoxicities and antitumor immunity. J Gene Med 2003; 5:668-80.
    • (2003) J Gene Med , vol.5 , pp. 668-680
    • Liu, Y.1    Huang, H.2    Chen, Z.3    Zong, L.4    Xiang, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.