Tumour necrosis factor-α (TNF-α) transgene-expressing dendritic cells (DCs) undergo augmented cellular maturation and induce more robust T-cell activation and anti-tumour immunity than DCs generated in recombinant TNF-α

Immunology

Volumn 108, Issue 2, 2003, Pages 177-188

  Zhang, Weidong ^a   Chen, Zhuang ^a   Li, Fang ^a   Kamencic, Huse ^a   Juurlink, Bernie ^a   Gordon, John R ^a   Xiang, Jim ^a,b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b Saskatoon Cancer Center   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BETA CHEMOKINE; CANCER VACCINE; CD40 ANTIGEN; CD8 ANTIGEN; CD86 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR CCR7; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 18; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MUT1 PEPTIDE; PEPTIDE; T LYMPHOCYTE RECEPTOR; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLOGENEIC RESTRICTION; ANIMAL CELL; ANTIGEN PRESENTATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DNA MODIFICATION; GENETIC TRANSFECTION; IMMUNE RESPONSE; LYMPHOID ORGAN; MOUSE; MUT1 PEPTIDE PULSED DENDRITIC CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TRANSGENE; VACCINATION; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; CANCER VACCINES; CELL DIFFERENTIATION; CHEMOTAXIS; DENDRITIC CELLS; GENETIC VECTORS; IMMUNITY, CELLULAR; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEOPLASMS, EXPERIMENTAL; RECOMBINANT PROTEINS; T-LYMPHOCYTES; TRANSFECTION; TRANSGENES; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037323941     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2003.01489.x     Document Type: Article

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