A loop of coagulation factor VIIa influencing macromolecular substrate specificity

FEBS Letters

Volumn 581, Issue 1, 2007, Pages 71-76

  Bjelke, Jais R ^a,b   Persson, Egon ^a   Rasmussen, Hanne B ^a   Kragelund, Birthe B ^b   Olsen, Ole H ^a  

^a NOVO NORDISK A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Allostery; Coagulation factor VIIa; Macromolecular substrate specificity; Met298 156

Indexed keywords

BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 9; LYSINE; METHIONINE; MUTANT PROTEIN;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BLOOD CLOTTING; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; MACROMOLECULE; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; BINDING SITES; BLOOD COAGULATION; ENZYME ACTIVATION; FACTOR VIIA; FACTOR XA; HUMANS; MULTIENZYME COMPLEXES; MUTATION, MISSENSE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; THROMBOPLASTIN;

EID: 33845665019     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.11.079     Document Type: Article

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