Human Cdc14A reverses CDK1 phosphorylation of Cdc25A on serines 115 and 320

Cell Cycle

Volumn 5, Issue 24, 2006, Pages 2894-2898

  Esteban, Verónica ^a   Vázquez Novelle, María D ^a   Calvo, Enrique ^b   Bueno, Avelino ^a   Sacristán, María P ^a,c  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^c Centro de Investigacion del Cancer   (Spain)

Author keywords

Cdc14A; Cdc25A; Cdk1 cyclin B1; Cell cycle; Dephosphorylation

Indexed keywords

CDC14A PHOSPHATASE; CDC25A PHOSPHATASE; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE; SERINE;

ARTICLE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL DIVISION; CELL VIABILITY; CENTROSOME; CONTROLLED STUDY; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; UPREGULATION;

SACCHAROMYCES CEREVISIAE;

EID: 33845636894     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.5.24.3566     Document Type: Article

References (38)

1. Visintin R, Craig K, Hwang ES, Prinz S, Tyers M, Amon A. The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. Mol Cell 1998; 2:709-18.
2. Jaspersen SL, Charles JF, Morgan DO. Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14. Curr Biol 1999; 9:227-36.
3. Shou W, Seol JH, Shevchenko A, Baskerville C, Moazed D, Chen ZW, Jang J, Charbonneau H, Deshaies RJ. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell 1999; 97:233-44.
4. Visintin R, Hwang ES, Amon A. Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus. Nature 1999; 398:818-23.
5. Cueille N, Salimova E, Esteban V, Blanco M, Moreno S, Bueno A, Simanis V. Flp1, a fission yeast orthologue of the s. cerevisiae CDC14 gene, is not required for cyclin degradation or rum1p stabilisation at the end of mitosis. J Cell Sci 2001; 114:2649-64.
6. 2/M transition and coordination of cytokinesis with cell cycle progression. Curr Biol 2001; 11:931-40.
7. Esteban V, Blanco M, Cueille N, Simanis V, Moreno S, Bueno A. A role for the Cdc14-family phosphatase Flp1p at the end of the cell cycle in controlling the rapid degradation of the mitotic inducer Cdc25p in fission yeast. J Cell Sci 2004; 117:2461-8.
8. 2/M transition and mitotic exit through Cdc25p inactivation. Embo J 2004; 23:919-29.
9. Gruneberg U, Glotzer M, Gartner A, Nigg EA. The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. J Cell Biol 2002; 158:901-14.
10. Saito RM, Perreault A, Peach B, Satterlee JS, van den Heuvel S. The CDC-14 phosphatase controls developmental cell-cycle arrest in C. elegans. Nat Cell Biol 2004; 6:777-83.
11. Kaiser BK, Nachury MV, Gardner BE, Jackson PK. Xenopus Cdc14 alpha/beta are localized to the nucleolus and centrosome and are required for embryonic cell division. BMC Cell Biol 2004; 5:27.
12. Li L, Ernsting BR, Wishart MJ, Lohse DL, Dixon JE. A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast. J Biol Chem 1997; 272:29403-6.
13. Mailand N, Lukas C, Kaiser BK, Jackson PK, Bartek J, Lukas J. Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation. Nat Cell Biol 2002; 4:317-22.
14. Kaiser BK, Zimmerman ZA, Charbonneau H, Jackson PK. Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase. Mol Biol Cell 2002; 13:2289-300.
15. Bembenek J, Yu H. Regulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14a. J Biol Chem 2001; 276:48237-42.
16. Gruneberg U, Neef R, Honda R, Nigg EA, Barr FA. Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2. J Cell Biol 2004; 166:167-72.
17. Li L, Ljungman M, Dixon JE. The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53. J Biol Chem 2000; 275:2410-4.
18. Paulsen MT, Starks AM, Derheimer FA, Hanasoge S, Li L, Dixon JE, Ljungman M. The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers. Mol Cancer 2006; 5:25.
19. Vazquez-Novelle MD, Esteban V, Bueno A, Sacristan MP. Functional homology among human and fission yeast Cdc14 phosphatases. J Biol Chem 2005; 280:29144-50.
20. 2. Proc Natl Acad Sci USA 1990; 87:5139-43.
21. Galaktionov K, Beach D. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins. Cell 1991; 67:1181-94.
22. Nagata A, Igarashi M, Jinno S, Suto K, Okayama H. An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells. New Biol 1991; 3:959-68.
23. Dunphy WG, Kumagai A. The cdc25 protein contains an intrinsic phosphatase activity. Cell 1991; 67:189-96.
24. Shiozaki K, Russell P. Stress-activated protein kinase pathway in cell cycle control of fission yeast. Methods Enzymol 1997; 283:506-20.
25. Shevchenko A, Wilm M, Vorm O, Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 1996; 68:850-8.
26. 2/M events by Cdc25A through phosphorylation-dependent modulation of its stability. Embo J 2002; 21:5911-20.
27. Jinno S, Suto K, Nagata A, Igarashi M, Kanaoka Y, Nojima H, Okayama H. Cdc25A is a novel phosphatase functioning early in the cell cycle. Embo J 1994; 13:1549-56.
28. Galaktionov K, Chen X, Beach D. Cdc25 cell-cycle phosphatase as a target of c-myc. Nature 1996; 382:511-7.
29. Vigo E, Muller H, Prosperini E, Hateboer G, Cartwright P, Moroni MC, Helin K. CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase. Mol Cell Biol 1999; 19:6379-95.
30. Donzelli M, Squatrito M, Ganoth D, Hershko A, Pagano M, Draetta GF. Dual mode of degradation of Cdc25 A phosphatase. Embo J 2002; 21:4875-84.
31. Busino L, Donzelli M, Chiesa M, Guardavaccaro D, Ganoth D, Dorrello NV, Hershko A, Pagano M, Draetta GF. Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage. Nature 2003; 426:87-91.
32. Busino L, Chiesa M, Draetta GF, Donzelli M. Cdc25A phosphatase: Combinatorial phosphorylation, ubiquitylation and proteolysis. Oncogene 2004; 23:2050-6.
33. Mailand N, Falck J, Lukas C, Syljuasen RG, Welcker M, Bartek J, Lukas J. Rapid destruction of human Cdc25A in response to DNA damage. Science 2000; 288:1425-9.
34. Molinari M, Mercuric C, Dominguez J, Goubin F, Draetta GF. Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis. EMBO Rep 2000; 1:71-9.
35. Falck J, Mailand N, Syljuasen RG, Bartek J, Lukas J. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 2001; 410:842-7.
36. 2 checkpoints. Proc Natl Acad Sci USA 2002; 99:14795-800.
37. 2 arrests through Cdc25A degradation in response to DNA-damaging agents. J Biol Chem 2003; 278:21767-73.
38. Sorensen CS, Syljuasen RG, Falck J, Schroeder T, Ronnstrand L, Khanna KK, Zhou BB, Bartek J, Lukas J. Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A. Cancer Cell 2003; 3:247-58.