Molecular basis for deficient acetaminophen glucuronidation in cats: An interspecies comparison of enzyme kinetics in liver microsomes

Biochemical Pharmacology

Volumn 53, Issue 7, 1997, Pages 1041-1047

  Court, Michael H ^a   Greenblatt, David J ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cats; enzyme kinetics; Gunn rats; microsomes; UDP glucuronosyltransferase acetaminophen

Indexed keywords

GLUCURONOSYLTRANSFERASE; PARACETAMOL;

ARTICLE; CAT; CONTROLLED STUDY; DRUG METABOLISM; ENZYME BINDING; ENZYME KINETICS; HOMOZYGOSITY; INTOXICATION; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE;

ACETAMINOPHEN; ANIMALS; CATS; DOGS; GLUCURONOSYLTRANSFERASE; HUMANS; KINETICS; MICROSOMES, LIVER; MUTATION; RATS; RATS, GUNN; SPECIES SPECIFICITY;

EID: 0031009017     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00072-5     Document Type: Article

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