Altering conserved lipid binding sites in cytochrome c oxidase of Rhodobacter sphaeroides perturbs the interaction between subunits I and III and promotes suicide inactivation of the enzyme

Biochemistry

Volumn 45, Issue 50, 2006, Pages 14896-14907

  Varanasi, Lakshman ^a   Mills, Denise ^c   Murphree, Anna ^a   Gray, Jimmy ^a   Purser, Chris ^b   Baker, Rodney ^b   Hosler, Jonathan ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^b UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^c Michigan State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CATALYSIS; ENZYMES; FATTY ACIDS; MUTAGENESIS;

CYTOCHROME C OXIDASE (CCO); PROTON DELIVERY; RHODOBACTER SPHAEROIDES; SUICIDE INACTIVATION;

LIPIDS;

ALANINE; ARGININE; BACTERIAL ENZYME; CYTOCHROME C OXIDASE; CYTOCHROME C OXIDASE I; CYTOCHROME C OXIDASE II; CYTOCHROME C OXIDASE III; FATTY ACID; LIPID; LIPID BINDING PROTEIN; MUTANT PROTEIN; OXYGEN; PHENYLALANINE; PHOSPHOLIPID; PROTEIN SUBUNIT; PROTON; SOYBEAN OIL; TRYPTOPHAN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INACTIVATION; ENZYME ISOLATION; ENZYME METABOLISM; ENZYME MODIFICATION; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; MOLECULAR MIMICRY; MUTATIONAL ANALYSIS; NONHUMAN; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTON TRANSPORT; REDUCTION; RHODOBACTER SPHAEROIDES; SOYBEAN;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; COPPER; ELECTRON TRANSPORT COMPLEX IV; ENZYME ACTIVATION; LIPIDS; OXIDATION-REDUCTION; OXYGEN; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS; RHODOBACTER SPHAEROIDES;

BACTERIA (MICROORGANISMS); GLYCINE MAX; RHODOBACTER SPHAEROIDES;

EID: 33845573535     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi061390q     Document Type: Article

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