Redox-driven membrane-bound proton pumps

Trends in Biochemical Sciences

Volumn 29, Issue 7, 2004, Pages 380-387

  Brzezinski, Peter ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

HEME; MEMBRANE PROTEIN; OXIDOREDUCTASE; OXYGEN; PROTON PUMP;

BIOENERGY; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTON TRANSPORT; REDUCTION; REVIEW; STOICHIOMETRY;

ANIMALS; ELECTRON TRANSPORT COMPLEX IV; INTRACELLULAR MEMBRANES; KINETICS; MODELS, MOLECULAR; OXIDATION-REDUCTION; PROTON PUMPS; THERMODYNAMICS;

HARNESS;

EID: 3242763877     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2004.05.008     Document Type: Review

References (56)

1. Rich P.R. The molecular machinery of Keilin's respiratory chain. Biochem. Soc. Trans. 31:2003;1095-1105
2. Mills D.A., Ferguson-Miller S. Understanding the mechanism of proton movement linked to oxygen reduction in cytochrome c oxidase: lessons from other proteins. FEBS Lett. 545:2003;47-51
3. Wikström M. Cytochrome c oxidase: 25 years of the elusive proton pump. Biochim. Biophys. Acta. 1655:2004;241-247
4. Svensson-Ek M., et al. The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides. J. Mol. Biol. 321:2002;329-339
5. Bratton M.R., et al. Suicide inactivation of cytochrome c oxidase: catalytic turnover in the absence of subunit III alters the active site. Biochemistry. 38:1999;16236-16245
6. Yoshikawa S., et al. Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase. Science. 280:1998;1723-1729
7. Tsukihara T., et al. The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 Å Science. 272:1996;1136-1144
8. Iwata S., et al. Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans. Nature. 376:1995;660-669
9. Ostermeier C., et al. Structure at 2.7 Å resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody FV fragment. Proc. Natl. Acad. Sci. U. S. A. 94:1997;10547-10553
10. Abramson J., et al. The structure of the ubiquinol oxidase from Escherichia coli and its ubiquinone binding site. Nat. Struct. Biol. 7:2000;910-917
11. 3-cytochrome c oxidase from Thermus thermophilus. EMBO J. 19:2000;1766-1776
12. Brzezinski P., et al. Functional aspects of heme-copper terminal oxidases. Zannoni D. Respiration in Archaea and Bacteria (Advances in Photosynthesis and Respiration). 2003;129-153 Kluwer Academic Publishers
13. Brandsburg-Zabary S., et al. Biophysical aspects of intra-protein proton transfer. Biochim. Biophys. Acta. 1458:2000;120-134
14. Wikström M., et al. Water-gated mechanism of proton translocation by cytochrome c oxidase. Biochim. Biophys. Acta. 1604:2003;61-65
15. Zheng X., et al. Computer simulation of water in cytochrome c oxidase. Biochim. Biophys. Acta. 1557:2003;99-107
16. Olkhova E., et al. Dynamic water networks in cytochrome c oxidase from Paracoccus denitrificans investigated by molecular dynamics simulations. Biophys. J. 86:2003;1873-1889
17. Brändén M., et al. On the role of the K-proton transfer pathway in cytochrome c oxidase. Proc. Natl. Acad. Sci. U. S. A. 98:2001;5013-5018
18. Pecoraro C., et al. Role of the K-channel in the pH-dependence of the reaction of cytochrome c oxidase with hydrogen peroxide. Biochemistry. 40:2001;9695-9708
19. Gennis R.B. Multiple proton-conducting pathways in cytochrome oxidase and a proposed role for the active-site tyrosine. Biochim. Biophys. Acta. 1365:1998;241-248
20. Fabian M., et al. Mass spectrometric determination of dioxygen bond splitting in the "peroxy" intermediate of cytochrome c oxidase. Proc. Natl. Acad. Sci. U. S. A. 96:1999;13114-13117
21. Proshlyakov D.A., et al. Oxygen activation and reduction in respiration: involvement of redox-active tyrosine 244. Science. 290:2000;1588-1591
22. Ogura T., Kitagawa T. Resonance Raman characterization of the P intermediate in the reaction of bovine cytochrome c oxidase. Biochim. Biophys. Acta. 1655:2004;290-297
23. Blomberg M.R.A., et al. O-O bond splitting mechanism in cytochrome oxidase. J. Inorg. Biochem. 80:2000;261-269
24. Babcock G.T., Wikström M. Oxygen activation and the conservation of energy in cell respiration. Nature. 356:1992;301-309
25. Paula S., et al. Proton and electron transfer during the reduction of molecular oxygen by fully reduced cytochrome c oxidase: a flow-flash investigation using optical multichannel detection. Biochemistry. 38:1999;3025-3033
26. Fabian M., Palmer G. Proton involvement in the transition from the "peroxy" to the ferryl intermediate of cytochrome c oxidase. Biochemistry. 40:2001;1867-1874
27. Namslauer A., et al. Intramolecular proton-transfer reactions in a membrane-bound proton pump: the effect of pH on the peroxy to ferryl transition in cytochrome c oxidase. Biochemistry. 42:2003;1488-1498
28. Konstantinov A.A. Cytochrome c oxidase as a proton-pumping peroxidase: reaction cycle and electrogenic mechanism. J. Bioenerg. Biomembr. 30:1998;121-130
29. Brzezinski P., Ädelroth P. Pathways of proton transfer in cytochrome c oxidase. J. Bioenerg. Biomembr. 30:1998;99-107
30. 3 from Rhodobacter sphaeroides is involved in proton uptake during the reaction of the fully-reduced enzyme with dioxygen. Biochemistry. 36:1997;13824-13829
31. Gennis R.B. Coupled proton and electron transfer reactions in cytochrome oxidase. Front. Biosci. 9:2004;581-591
32. Babcock G.T. How oxygen is activated and reduced in respiration. Proc. Natl. Acad. Sci. U. S. A. 96:1999;12971-12973
33. Michel H. The mechanism of proton pumping by cytochrome c oxidase. Proc. Natl. Acad. Sci. U. S. A. 95:1998;12819-12824
34. Michel H. Cytochrome c oxidase: catalytic cycle and mechanisms of proton pumping - a discussion. Biochemistry. 38:1999;15129-15140
35. Verkhovsky M.I., et al. Proton translocation by cytochrome c oxidase. Nature. 400:1999;480-483
36. Ruitenberg M., et al. Reduction of cytochrome c oxidase by a second electron leads to proton translocation. Nature. 417:2002;99-102
37. Bloch D., et al. The catalytic cycle of cytochrome c oxidase is not the sum of its two halves. Proc. Natl. Acad. Sci. U. S. A. 101:2004;529-533
38. 13C labeling. Biochemistry. 37:1998;7400-7406
39. Hofacker I., Schulten K. Oxygen and proton pathways in cytochrome c oxidase. Proteins Struct. Funct. Genet. 30:1998;100-107
40. Puustinen A., Wikström M. Proton exit from the heme-copper oxidase of Escherichia coli. Proc. Natl. Acad. Sci. U. S. A. 96:1999;35-37
41. Ädelroth, P. et al. Proton transfer from glutamate 286 determines the transition rates between oxygen intermediates in cytochrome c oxidase. Biochim. Biophys. Acta 1459, 533-539.
42. Papa S., et al. A cooperative model for protonmotive heme-copper oxidases. The role of heme a in the proton pump of cytochrome c oxidase. FEBS Lett. 439:1998;1-8
43. Xavier A.V. A mechano-chemical model for energy transduction in cytochrome c oxidase: the work of a Maxwell's god. FEBS Lett. 532:2002;261-266
44. Rich P.R., et al. Protonmotive mechanism of heme-copper oxidases. J. Bioenerg. Biomembr. 30:1998;131-138
45. Tsukihara T., et al. The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process. Proc. Natl. Acad. Sci. U. S. A. 100:2003;15304-15309
46. Mills D.A., Ferguson-Miller S. Influence of structure, pH and membrane potential on proton movement in cytochrome oxidase. Biochim. Biophys. Acta. 1555:2002;96-100
47. Popovic D.M., Stuchebrukhov A.A. Proton pumping mechanism and catalytic cycle of cytochrome c oxidase: Coulomb pump model with kinetic gating. FEBS Lett. 2004;. doi:10.1016/j.febslet.2004.04.016
48. Pfitzner U., et al. Tracing the D-pathway in reconstituted site-directed mutants of cytochrome c oxidase from Paracoccus denitrificans. Biochemistry. 39:2000;6756-6762
49. Pawate A.S., et al. A mutation in subunit I of cytochrome oxidase from Rhodobacter sphaeroides results in an increase in steady-state activity but completely eliminates proton pumping. Biochemistry. 41:2002;13417-13423
50. Namslauer A., et al. Redox-coupled proton translocation in biological systems: proton shuttling in cytochrome c oxidase. Proc. Natl. Acad. Sci. U. S. A. 100:2003;15543-15547
51. Brzezinski P., Larsson G. Redox-driven proton pumping by heme-copper oxidases. Biochim. Biophys. Acta. 1605:2003;1-13
52. Mitchell P. Coupling of phosphorylation to electron and hydrogen transfer by a chemiosmotic type of mechanism. Nature. 191:1961;144-148
53. Brunori M., et al. Investigating the mechanism of electron transfer to the binuclear center in Cu-heme oxidases. J. Bioenerg. Biomembr. 30:1998;41-45
54. Schmidt B., et al. A discrete water exit pathway in the membrane protein cytochrome c oxidase. Proc Natl Acad Sci U. S. A. 100:2003;15539-15542
55. Mills D.A., et al. A role for subunit III in proton uptake into the D pathway and a possible proton exit pathway in Rhodobacter sphaeroides cytochrome c oxidase. Biochemistry. 42:2003;7410-7417
56. Humphrey W., et al. VMD: visual molecular dynamics. J. Molecular Graphics. 14:1996;33-38