Slow proton transfer through the pathways for pumped protons in cytochrome c oxidase induces suicide inactivation of the enzyme

Biochemistry

Volumn 44, Issue 12, 2005, Pages 4656-4666

  Mills, Denise A ^a   Hosler, Jonathan P ^b  

^a Michigan State University   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CHARGE TRANSFER; COMPLEXATION; MUTAGENESIS; PH EFFECTS; PROTONS;

ARACHIDONIC ACIDS; OXIDASE; PROTON PUMP; PROTON TRANSFER;

ENZYMES;

ARACHIDONIC ACID; CYTOCHROME C OXIDASE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME SUBUNIT; MUTATION; PRIORITY JOURNAL; PROTON TRANSPORT;

ANIMALS; ARACHIDONIC ACID; BINDING SITES; CATALYSIS; ELECTRON TRANSPORT COMPLEX IV; ENZYME ACTIVATION; GLUTAMIC ACID; HORSES; HYDROGEN-ION CONCENTRATION; OXIDATION-REDUCTION; PROTEIN SUBUNITS; PROTON PUMPS; RHODOBACTER SPHAEROIDES; SURFACE PROPERTIES; THREONINE;

EID: 15444369621     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0475774     Document Type: Article

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