Expression of CXCR-1 and CXCR-2 chemokine receptors on synovial neutrophils in inflammatory arthritides: Does persistent or increasing expression of CXCR-2 contribute to the chronic inflammation or erosive changes?

Joint Bone Spine

Volumn 73, Issue 6, 2006, Pages 691-696

  Pay, Salih ^a   Musabak, Ugur ^a   Şimşek, Ismail ^a   Pekel, Aysel ^a   Erdem, Hakan ^a   Dinç, Ayhan ^a   Şengül, Ali ^a  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

Author keywords

Beh et's disease; Chemokine receptor; CXCR 1; CXCR 2; ENA 78; GCP 2; GRO ; IL 8; Rheumatoid arthritis

Indexed keywords

CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2;

ARTICLE; BEHCET DISEASE; CELL ISOLATION; CHRONIC INFLAMMATION; CLINICAL ARTICLE; CLINICAL FEATURE; COMPARATIVE STUDY; CONTROLLED STUDY; EROSION; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; NEUTROPHIL; OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; CHRONIC DISEASE; FEMALE; IMMUNOLOGY; MALE; METABOLISM; PATHOLOGY; SYNOVIUM;

ARTHRITIS, RHEUMATOID; BEHCET SYNDROME; CHRONIC DISEASE; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; NEUTROPHILS; OSTEOARTHRITIS; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; SYNOVIAL FLUID; SYNOVIAL MEMBRANE;

EID: 33845499029     PISSN: 1297319X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbspin.2006.01.023     Document Type: Article

References (36)

1. Moser B., and Loetscher P. Lymphocyte traffic control by chemokines. Nat. Immunol. 2 (2001) 1-7
2. Cravens P.D., and Lipksy P.E. Dendritic cells, chemokine receptors and autoimmune inflammatory disease. Immunol. Cell Biol. 80 (2002) 497-505
3. McColl S.R. Chemokines and dentritic cells: a crucial alliance. Immunol. Cell Biol. 80 (2002) 489-496
4. Koch A.E., Polverini P.J., Kunkel S.L., Harlow L.A., Dipietro L.A., Elner V.M., et al. Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science 21 (1995) 447-448
5. Szekanecz Z., and Koch A.E. Chemokines and angiogenesis. Curr. Opin. Rheumatol. 13 (2000) 202-208
6. Belperio J.A., Keane P.M., Arenberg D.A., Addison C.L., Ehlert J.A., Burdick M.D., et al. CXC chemokines in angiogenesis. J. Leukocyte Biol. 68 (2000) 1-8
7. Szekanecz Z., Kim J., and Koch A.E. Chemokines and chemokine reseptors in rheumatoid arthritis. Semin. Immunol. 15 (2003) 15-21
8. Sixt M., Hallmann R., Wendler O., Scharffetter-Kochanek K., and Sorokin L.M. Cell adhesion and migration properties of β2 integrin polymorphonuclear granulocytes on defined extracellular matrix molecules. J. Biol. Chem. 276 (2001) 18878-18887
9. Liu-Bryan R., Pay S., Schraufstatter I.U., and Rose D.M. The CXCR1 tail mediates β1 integrin-dependent cell migration via map kinase signaling. Biochem. Biophys. Res. Commun. 332 (2005) 402-410
10. Erdem H., Pay S., Serdar M., Simsek I., Dinc A., Musabak U., et al. Different ELR (+) angiogenic CXC chemokine profiles in synovial fluid of patients with Behçet's disease, Familial Mediterranean fever, rheumatoid arthritis, and osteoarthritis. Rheumatol. Int. 26 (2005) 162-167
11. Buckley C.D. Why do leucocytes accumulate within chronically inflamed joints?. Rheumatology 42 (2003) 1433-1444
12. Tak P.P. Is early rheumatoid arthritis the same disease process as late rheumatoid arthritis?. Best Pract. Res. Clin. Rheumatol. 15 (2001) 17-26
13. Peichl P., Ceska M., Effenberg F., Haberhauer G., Broell H., and Lindley I.J. Presence of NAP-1/IL-8 in synovial fluids indicates a possible pathogenic role in rheumatoid arthritis. Scand. J. Immunol. 34 (1991) 333-339
14. Walz A., Schumutz P., Mueller C., and Schnyder-Candrian S. Regulation and function of the CXC chemokines ENA-78 in monocytes and its role in disease. J. Leukocyte Biol. 62 (1997) 604-611
15. Koch A.E., Kunkel S.L., Harlow L.A., Mazarakis D.D., Haines G.K., Burdick M.D., et al. Epithelial neutrophil activating peptide-78: a novel chemotactic cytokine for neutrophils in arthritis. J. Clin. Invest. 94 (1994) 1012-1018
16. Koch A.E., Kunkel S.L., Shah M.R., Hosaka S., Halloran M.M., Haines G.K., et al. Growth-related gene product alpha. A chemotactic cytokine for neutrophils in rheumatoid arthritis. J. Immunol. 155 (1995) 3660-3666
17. Damme J.V., Wuyts A., Froyen G., Coillie E.V., Struyf S., Billiau A., et al. Granulocyte chemotactic protein-2 related CXC chemokines: from gene regulation to receptor usage. J. Leukocyte Biol. 62 (1997) 563-569
18. Godaly G., Hang L., Frendeus B., and Svanborg C. Transepithelial neutrophil migration is CXCR-1 dependent in vitro and is defective in IL-8 receptor knockout mice. J. Immunol. 165 (2000) 5287-5294
19. Khandaker M.H., Xu L., Rahimpour R., Mitchell G., De Viries M.E., Pickering J.G., et al. CXCR1 and CXCR2 are rapidly down-modulated by bacterial endotoxin through a unique agonist-independent, tyrosine kinase-dependent mechanism. J. Immunol. 161 (1998) 930-938
20. Asogoe K., Yamamoto K., Takahashi A., Suzuki K., Maeda A., Nohgawa M., et al. Down-regulation of CXCR-2 expression on human polymorhonuclear leukocytes by TNF-alpha. J. Immunol. 160 (1998) 4518-4525
21. Bonecchi R., Polentarutti N., Luini W., Borsatti A., Bernasconi S., Locati M., et al. Up-regulation of CCR1 and CCR3 and induction of chemotaxis to CC chemokines by IFN-gamma in human neutrophils. J. Immunol. 162 (1999) 474-479
22. Johnston B., Burns A.R., Suematsu M., Issekutz T.B., Woodman R.C., and Kubes P. Chronic inflammation upregulates chemokine receptors and induces neutrophil migration to monocyte chemoattractant protein-1. J. Clin. Invest. 103 (1999) 1269-1276
23. Yamashiro S., Kamohara H., Wang J.M., Yang D., Gong W.H., and Yoshimura T. Phenotypic and functional change of cytokine-activated neutrophils: inflammatory neutrophils are heterogeneous and enhance adaptive immune responses. J. Leukocyte Biol. 69 (2001) 698-704
24. Williams E.J., Haque S., Banks C., Johnson P., Sarsfield P., and Sheron N. Distribution of IL-8 receptors, CXCR-1 and CXCR-2, in inflamed gut tissue. J. Pathol. 192 (2002) 533-539
25. Ohtani N., Ohtani H., Oki M., Naganuma H., and Nagura H. CXC chemokine receptor 1 (CXCR1) is expessed mainly by neutrophils in inflamed gut and stomach tissues. Tohoku J. Exp. Med. 196 (2002) 179-184
26. Cummings C.J., Martin T.R., Frevert C.W., Quan J.M., Wong V.A., Mongovin S.M., et al. Expression and function of the chemokine receptors CXCR-1 and CXCR-2 in sepsis. J. Immunol. 162 (1999) 2341-2346
27. Podolin P.L., Bolognese B.J., Foley J.J., Schmidt D.B., Buckley P.T., Widdowson K.L., et al. A potent and selective nonpeptide antagonist of CXCR2 inhibits acute and chronic models of arthritis in the rabbit. J. Immunol. 169 (2002) 6435-6444
28. Wang C.R., Liu M.F., Huang Y.H., and Chen H.C. Up-regulation of XCR1 expression in rheumatoid joints. Rheumatology 43 (2004) 569-573
29. Ruschpler P., Lorenz P., Eichler W., Koczan D., Hänel C., Scholz R., et al. High CXCR3 expression in synovial mast cells associated with CXCL9 and CXCL10 expression in inflammatory synovial tissues of patients with rhematoid arthritis. Arthritis Res. Ther. 5 (2003) R241-RR52
30. Ruth J.H., Rottman J.B., Katschke K.J., Qin S., Wu L., Larosa G., et al. Selective lymphocyte chemokine receptor expression in the rheumatoid joint. Arhritis and Rheumatism 44 (2001) 2750-2760
31. Matsui T., Akahoshi R., Namai R., Hashimoto A., Kurihara Y., Rana M., et al. Selective recruitment of CCR6-expressing cells by increased production of MIP-3α in rheumatoid arthritis. Clin. Exp. Immunol. 125 (2001) 155-161
32. Katschke Jr. K.J., Rottman J.B., Ruth J.H., Qin S., Wu L., Larosa G., et al. Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis. Arthritis Rheum. 44 (2001) 1022-1033
33. Patel D.D., Zachariah J.P., and Whichard L.P. CXCR3 and CCR5 ligands in rheumatoid arthritis synovium. Clin. Immunol. 98 (2001) 39-45
34. Mack M., Brühl H., Gruber R., Jaeger C., Cihak J., Eiter V., et al. Predominance of mononuclear cells expressing the chemokine receptor CCR5 in synovial effusions of patients with different forms of arthritis. Arthritis Rheum. 42 (1999) 981-988
35. Galligan C.L., Matsuyama W., Matsukawa A., Mizuta H., Hodge D.R., Howard O.M.Z., et al. Up-regulated expression and activation of the orphan chemokine receptor, CCRL2, in rheumatoid arthritis. Arthritis Rheum. 50 (2004) 1806-1814
36. Brühl H., Wagner K., Kellner H., Schattenkirchner M., Schlöndorff D., and Mack M. Surface expression of CC- and CXC-chemokine receptors on leukocyte subsets in inflammatory joint diseases. Clin. Exp. Immunol. 126 (2001) 551-559