DNA damage and mutagenicity induced by endosulfan and its metabolites

Environmental and Molecular Mutagenesis

Volumn 47, Issue 9, 2006, Pages 682-692

  Bajpayee, Mahima ^a   Pandey, Alok Kumar ^a   Zaidi, Sabina ^b   Musarrat, Javed ^b   Parmar, Devendra ^a   Mathur, Neeraj ^a   Seth, Prahlad Kishore ^a   Dhawan, Alok ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

CHO cells; Comet assay; Endosulfan and metabolites; Human lymphocytes; Salmonella mutagenicity assay

Indexed keywords

DNA; ENDOSULFAN; ENDOSULFAN DIOL; ENDOSULFAN ETHER; ENDOSULFAN HYDROXYETHER; ENDOSULFAN LACTONE; ENDOSULFAN SULFATE; ETHER DERIVATIVE; LACTONE DERIVATIVE; SULFATE; TOXIN;

AMES TEST; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL MUTATION; BACTERIAL STRAIN; CHO CELL; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DAMAGE; GASTROINTESTINAL TOXICITY; GENE MUTATION; GENOTOXICITY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INDUCED MUTATION; ISOMER; LD 50; LYMPHOCYTE; MALE; MAMMAL CELL; METABOLITE; MUTAGENICITY; NONHUMAN; NORMAL HUMAN; SALMONELLA; STATISTICAL SIGNIFICANCE;

ANIMALS; CELL SURVIVAL; CHO CELLS; COMET ASSAY; CRICETINAE; CRICETULUS; DNA DAMAGE; ENDOSULFAN; HUMANS; INSECTICIDES; LYMPHOCYTES; MALE; MUTAGENS; SALMONELLA TYPHIMURIUM;

AVES; BACTERIA (MICROORGANISMS); BOS TAURUS; CRICETULUS GRISEUS; MAMMALIA; SALMONELLA;

EID: 33845497003     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20255     Document Type: Article

References (46)

1. Agency for toxic substances and disease registry (ATSDR) 2000, Toxicological profile on Endosulfan. Available at http://www.atsdr.cdc. gov/toxprofiles/tp41.html.
2. Andersen HR, Vinggaard AM, Rasmussen TH, Gjermandsen IM, Bonefeld-Jorrgensen EC. 2002. Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro. Toxicol Appl Pharmacol 179:1-12.
3. Bajpayee M, Pandey AK, Parmar D, Mathur N, Seth PK, Dhawan A. 2005. Comet assay responses in human lymphocytes are not influenced by the menstrual cycle: A study in healthy Indian females. Mutat Res 565:163-172.
4. Barnes W, Tuley E. Eisenstadt E. 1982. Base sequence analysis of His revenants of the his G46 missense mutation in Salmonella typhimurium. Environ Mutagen 4:297 (abstract Aa-1).
5. Bebe FN, Panemangalore M. 2003. Exposure to low doses of Endosulfan and Chlorpyrifos modifies endogenous antioxidants in tissues of rats. J Environ Sci Health B 38:349-363.
6. Chaudhuri K, Selvaraj S, Pal AK. 1999. Studies on the genotoxicity of endosulfan in bacterial systems. Mutat Res 439:63-67.
7. Choudhary N, Sharma M, Verma P, Joshi SC. 2003. Hepato and nephrotoxicity in rat exposed to endosulfan. J Environ Biol 24:305-308.
8. Dehn PF, Allen-Mocherie S, Karek J, Thenappan A. 2005. Organ chlorine insecticides: Impacts on human HepG2 cytochrome P4501A, 2B activities and glutathione levels. Toxicol In Vitro 19:261-273.
9. Dey A, Parmar D, Dayal M, Dhawan A, Seth PK. 2001. Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes evidence for catalytic activity and mRNA expression. Life Sci 69:383-393.
10. Dubois M, Pfhol-Leszkowicz A, De Waziers I, Kremers P. 1996. Selective induction of the CYP3A family by endosulfan and DNA adduct formation in different hepatic and hepatoma cells. Environ Toxicol Pharmacol 1:249-256.
11. EXTOXNET. Available at http://extoxnet.orst.edu/pips/endosulf.htm.
12. Falck GC, Hirvonen A, Scarpato R, Saarikoski ST, Migliore L, Norppa H. 1999. Micronuclei in blood lymphocytes and genetic polymorphism for GSTM1, GSTT1 and NAT2 in pesticide-exposed greenhouse workers. Mutat Res 441:225-237.
13. Isono K, Yourno J. 1974. Chemical carcinogens as frameshift mutagens: Salmonella DNA sequence sensitive to mutagenesis by polycyclic carcinogens. Proc Natl Acad Sci USA 71:1612-1617.
14. Jamil K, Shaik AP, Mahboob M, Krishna D. 2004. Effect of organophosphorus and organochlorine pesticides (monochrotophos, chlorpyriphos, dimethoate, and endosulfan) on human lymphocytes in vitro. Drug Chem Toxicol 27:133-144.
15. Joshi S. 2001. A curse called endosulfan: A Kerala village blames aerial spraying of the pesticide endosulfan for unusual diseases. Down to Earth 9:28-35.
16. Kalender S, Kalender Y, Ogutcu A, Uzunhisarcikli M, Durak D, Acikgoz F. 2004. Endosulfan-induced cardiotoxicity and free radical metabolism in rats: The protective effect of vitamin E. Toxicology 202:227-235.
17. Kannan K, Jain SK. 2003. Oxygen radical generation and endosulfan toxicity in Jurkat T-cells. Mol Cell Biochem 247:1-7.
18. Kannan K, Holcombe RF, Jain SK, Alvarez-Hernandez X, Chervenak R, Wolf RE, Glass J. 2000. Evidence for the induction of apoptosis by endosulfan in a human T-cell leukemic line. Mol Cell Biochem 205:53-66.
19. Kelly BC, Gobas FA. 2003. An arctic terrestrial food-chain bioaccumulation model for persistent organic pollutants. Environ Sci Technol 37:2966-2974.
20. Ledirac N, Antherieu S, d'Uby AD, Caron JC, Rahmani R. 2005. Effects of organochlorine insecticides on MAP kinase pathways in human HaCaT keratinocytes: Key role of reactive oxygen species. Toxicol Sci 86:444-452.
21. Levin DE, Yamasaki E, Ames BN. 1982a. A new Salmonella tester strain for the detection of frame shift mutagens: A run of cytosines as a mutational hot spot. Mutat Res 94:315-330.
22. Levin DE, Hollstein M, Christman MF, Schwiers E, Ames BN. 1982b. A new Salmonella tester strain (TA102) with A-T base pairs at the site of mutation detects oxidative mutagens. Proc Natl Acad Sci USA 79:7445-7449.
23. Lu Y, Morimoto K, Takeshita T, Takeuchi T, Saito T. 2000. Genotoxic effects of α-Endosulfan and β-endosulfan on human HepG2 cells. Environ Health Perspect 108:559-561.
24. Maron DM, Ames BN. 1983. Revised methods for the Salmonella mutagenicity test. Mutat Res 113:173-215.
25. Mor F, Ozmen O. 2003. Acute endosulfan poisoning in cattle. Vet Hum Toxicol 45:323,324.
26. Moriya M, Ohata T, Watanabe K, Miyazawa T, Kato K, Shirasu Y. 1983. Further mutagenicity studies on pesticides in bacteria reversion assay systems. Mutat Res 116:185-216.
27. Naqvi SM, Newton DJ. 1990. Bioaccumulation of endosulfan (Thiodan insecticide) in the tissues of Louisiana crayfish, Procambarus clarkia. J Environ Sci Health B 25:511-526.
28. Naqvi SM, Vaishnavi C. 1993. Bioaccumulative potential and toxicity of endosulfan insecticide to non-target animals. Comp Biochem Physiol C 105:347-361.
29. Pandey S, Ahmad I, Parvez S, Bin-Hafeez B, Haque R, Raisuddin S. 2001. Effect of endosulfan on antioxidants of freshwater fish Channa punctatus Bloch, Part 1: Protection against lipid peroxidation in liver by copper preexposure. Arch Environ Contam Toxicol 41:345-352.
30. Paul V, Balasubramaniam E. 1997. Effects of single and repeated administration of endosulfan on behaviour and its interaction with centrally acting drugs in experimental animals: A mini review. Environ Toxicol Pharmacol 3:151-157.
31. Pednekar MD, Gandhi SR, Netrawali MS. 1987. Evaluation of mutagenic activities of endosulfan, malathione and permethrin, before and after metabolic activation in the Ames Salmonella test. Bull Environ Contam Toxicol 38:925-933.
32. Phillips HJ. 1973. Dye exclusion tests for cell viability. In: Kruse PF, Patterson MJ, editors. Tissue Culture: Methods and Applications. New York: Academic Press. pp 406-408.
33. Plewa MJ, Kargalioglu Y, Vankerk D, Minear RA, Wagner ED. 2002. Mammalian cell cytotoxicity and genotoxicity analysis of drinking water disinfection by-products. Environ Mol Mutagen 4:134-142.
34. Raucy JL, Ingelman-Sundberg M, Carpenter S, Rannug A, Rane A, Franklin M, Romkes M. 1999. Drug metabolizing enzymes in lymphocytes. J Biochem Mol Toxicol 13:223-226.
35. Scarpato R, Migliore L, Angotzi G, Fedi A, Miligi L, Loprieno N. 1996. Cytogenetic monitoring of a group of Italian floriculturists: No evidence of DNA damage related to pesticide exposure. Mutat Res 367:73-82.
36. Scippo ML, Argiris C, Van De Weerdt C, Muller M, Willemsen P, Martial J, Maghuin-Rogister G. 2004. Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors. Anal Bioanal Chem 378:664-669.
37. Siddiqui AH, Ahmad M. 2003. The Salmonella mutagenecity of industrial, surface and ground water samples of Aligarh region of India. Mutat Res 541:21-29.
38. Simonich SL, Hites RA. 1995. Global distribution of persistent organochlorine compounds. Science 269:1851-1854.
39. Sobti RC, Krishan A, Davies J. 1983. Cytokinetic and cytogenetic effect of agricultural chemicals on human lymphoid cells in vitro. II. Organochlorine pesticides. Arch Toxicol 52:221-231.
40. Sohn HY, Kwon CS, Kwon GS, Lee JB, Kim E. 2004. Induction of oxidative stress by endosulfan and protective effect of lipid-soluble antioxidants against endosulfan-induced oxidative damage. Toxicol Lett 151:357-365.
41. Teepe AG, Beck DJ, Li AP. 1992. Comparison of rat liver parenchymal and nonparenchymal cells in the activation of promutagens. Environ Mol Mutagen 20:134-139.
42. Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H, Miyamae Y, Rojas E, Ryu JC, Sasaki YF. 2000. Single cell gel/Comet assay: Guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 35:206-221.
43. Velazquez A, Lontie JF, Schoofs L, Larebeka NV. 1984. Mutagenicity of the insecticide endosulfan in Drosophila melanogaster. Mutat Res 136:115-118.
44. Wan MT, Kuo JN, Buday C, Schroeder G, Van Aggelen G, Pasternak J. 2005. Toxicity of α-, β-, (α + β)-endosulfan and their formulated and degradation products to Daphnia magna, Hyalella azteca, Oncorhynchus mykiss, Oncorhynchus kisutch, and biological implications in streams. Environ Toxicol Chem 24:1146-1154.
45. World Health Organization (WHO). 1999. Pesticide residues in food-1998 evaluations. II. Toxicological. WHO/PCS/99.18 (nos 943-956 on INCHEM).
46. Yadav AS, Vashishta RK, Kakar SN. 1982. Testing of endosulfan and fenitrothion for genotoxicity in Saccharomyces cerevisiae. Mutat Res 105:403-407.