Cytogenetic monitoring of a group of Italian floriculturists: No evidence of DNA damage related to pesticide exposure

Mutation Research - Genetic Toxicology

Volumn 367, Issue 2, 1996, Pages 73-82

  Scarpato, R ^a   Migliore, L ^a   Angotzi, G ^a   Fedi, A ^a   Miligi, L ^a   Loprieno, N ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Chromosome aberration; Italian floriculturist; Micronuclei; Pesticide exposure; Sister chromatid exchange

Indexed keywords

PESTICIDE;

ADULT; AGRICULTURAL WORKER; ARTICLE; BIOLOGICAL MONITORING; CONTROLLED STUDY; CYTOGENETICS; DNA DAMAGE; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; ITALY; MAJOR CLINICAL STUDY; MALE; MICRONUCLEUS; MULTIPLE REGRESSION; OCCUPATIONAL EXPOSURE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SISTER CHROMATID EXCHANGE; SMOKING; STRUCTURAL CHROMOSOME ABERRATION;

EID: 0029926177     PISSN: 01651218     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-1218(95)00071-2     Document Type: Article

References (48)

1. Andersson, H.C. (1993) The spontaneous frequency of chromosomal aberrations and sister-chromatid exchanges in cultured peripheral lymphocytes of a single blood donor sampled more than 200 times. Mutation Res., 286, 281-292.
2. Anderson, D., A.J. Francis, P. Godbert, P.C. Jenkinson and K.R. Butterworth (1991) Chromosome aberrations (CA), sister-chromatid exchanges (SCE) and mitogen-induced blastogenesis in cultured peripheral lymphocytes from 48 control individuals sampled 8 times over 2 years. Mutation Res., 250, 467-476.
3. Bauchinger, M., J. Dresp, E. Schmid and R. Hauf (1982) Chromosome changes in lymphocytes after occupational exposure to pentachlorophenol (PCP), Mutation Res., 102, 83-88.
4. Blair, A. and S.H. Zahm (1991) Cancer among farmers, in: Hanley and Belfus (Eds.) Occupational Medicine: State of the Art Reviews. Philadelphia, pp. 335-354.
5. Bolognesi, C., M. Parrini, S. Bonassi, G. Ianello and A. Salanitto (1993) Cytogenetic analysis of a human population occupationally exposed to pesticides, Mutation Res., 285, 239-249.
6. Bonassi, S., M. Ceppi, V. Fontana and F. Merlo (1994) Multiple regression analysis of cytogenetic human data. Mutation Res., 313, 69-84.
7. Carhonell, E., M. Puig, N. Xamena, A. Creus and R. Marcos (1990) Sister chromatid exchange in lymphocytes of agricultural workers exposed to pesticides. Mutagenesis. 5, 403-405.
8. Carbonell, E., M. Puig, N. Xamena, A. Creus and R. Marcos (1991) Sister-chromatid exchanges (SCE) induced by p-dichlorobenzene in cultured human lymphocytes. Mutation Res., 263, 57-59.
9. Carbonell. E., N. Xamena, A. Creus and R. Marcos (1993) Cytogenetic biomonitoring in a Spanish group of agricultural workers exposed to pesticides, Mutagenesis. 8, 511-517.
10. Carrano, A.V. and A.T. Natarajan (1988) Considerations for population monitoring using cytogenetic techniques. Mutation Res., 204, 379-406.
11. Czeizel, A., T. van Bao, L. Szabó and P. Ruzicska (1973) Human chromosome aberrations in acute organic phosphorous acid ester (pesticide) intoxications. Mutation Res., 21, 187-188.
12. Czeizel. A., J. Király and P. Ruzicska (1975) Studies on chromosomal mutations in workers producing organophosphate insecticides, Mutation Res., 29, 279.
13. De Ferrari, M., M. Artuso, S. Bonassi, S. Bonatti, Z. Cavalieri, D. Pescatore, E. Marchini, V. Pisano and A. Abbondandolo (1991) Cytogenetic biomonitoring of an Italian population exposed to pesticides: chromosome aberration and sister-chromatid exchange analysis in peripheral blood lymphocytes. Mutation Res., 260, 105-113.
14. Desi, I., M. Palotas, G. Vetro, I. Csolle, M. Nehez, M. Zimanyi, A. Ferke, E. Huszta and L. Nagymajtenyi (1986) Biological monitoring and health surveillance of a group of greenhouse pesticide sprayers. Toxicol. Lett., 33, 91-105.
15. Dolara, P., M. Salvadori, T. Capobianco and F. Torricelli (1992) Sister-chromatid exchanges in human lymphocytes induced by dimethoate, omethoate, deltamethrin, benomyl and their mixture. Mutation Res., 283, 113-118.
16. Dolout, F.N., M.C. Pastori, O.A. Olivero, M. Gonzalèz Cid, D. Loria, E. Matos, N. Sobel, B.C. de Bujan and N. Albiano (1985) Sister-chromatid exchanges and chromosomal aberrations in a population exposed to pesticides. Mutation Res., 143, 237-244.
17. Dolout, F.N., M.C. Pastori, M. Gonzalèz Cid, E. Matos, H.N. von Guradze, C.R. Maderna, D. Loria, L. Sainz, N. Albiano and N. Sobel (1987) Cytogenetic analysis in plant breeders. Mutation Res., 189, 381-386.
18. Fenech, M. (1993) The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human population. Mutation Res., 285, 35-44.
19. Fenech, M., S. Neville and J. Rinaldi (1994) Sex is an important variable affecting spontaneous micronucleus frequency in cytokinesis-blocked lymphocytes, Mutation Res., 313, 203-207.
20. Gòmez-Arroyo, S., N. Noriega-Aldana, A. Osorio, F. Galicia, S. Ling and R. Villalobos-Pietrini (1992) Sister-chromatid exchange in a rural population of Mexico exposed to pesticides. Mutation Res., 281, 173-179.
21. Högstedt, B., A.M. Kolnig, F. Mitelman and S. Skerfving (1980) Cytogenetic study of pesticides in agricultural work, Hereditas, 92, 177-178.
22. Jablonickà, A., H. Polàkovà, J. Karelovà and M. Vargovà (1989) Analysis of chromosome aberrations and sister-chromatid exchanges in peripheral blood lymphocytes of workers with occupational exposure to the mancozeb-containing fungicide Novozir Mn 80, Mutation Res., 224, 143-146.
23. Kapp, R.W.Jr., D.J. Picciano and C.B. Jacobson (1979) Y-chromosomal nondisjunction in dibromochloropropane- exposed workmen, Mutation Res., 64, 47-51.
24. Kourakis, A., M. Mouratidou, G. Kokkinos, A. Barbouti, A. Kotsis, D. Mourelatos and J. Dozi-Vassiliades (1992) Frequencies of chromosomal aberrations in pesticide sprayers working in plastic green houses. Mutation Res., 279, 145-148.
25. Lazutka, J.R., V. Dedonyte and Krapavickaite (1994) Sister-chromatid exchanges and their distribution in human lymphocytes in relation to age, sex and smoking, Mutation Res., 306, 173-180.
26. Linnainmaa, K. (1983) Sister chromatid exchanges among workers occupationally exposed to phenoxy acid herbicides 2,4-D and MCPA, Teratogen. Carcinogen. Mutagen., 3, 269-279.
27. Livingston, G.K., J.E. Lockey, K.S. Witt and S.W. Rogers (1985) An unstable giant satellite associated with chromosomes 21 and 22 in the same individual, Am. J. Hum. Genet., 37, 553-560.
28. Migliore, L., M. Parrini, I. Sbrana, C. Biagini, A. Battaglia and N. Loprieno (1991) Micronucleated lymphocytes in people occupationally exposed to potential environmental contaminants: the age effect, Mutation Res., 256, 13-20.
29. Morgan, W.F. and P.E. Crossen (1977) The incidence of sister chromatid exchanges in cultured human lymphocytes. Mutation Res., 42, 305-312.
30. Pàldy, A., N. Puskàs, K. Vincze and M. Hadhàzi (1987) Cytogenetic studies on rural populations exposed to pesticides. Mutation Res., 187, 127-132.
31. Perry, P. and S. Wolff (1974) New Giemsa method for differential staining of sister chromatids, Nature, 25, 156-158.
32. Piatti, E., L. Marabini and E. Chiesara (1994) Increase of micronucleus frequency in cultured rat hepatocytes treated in vitro with benomyl and pirimiphos-methyl separately and in mixture. Mutation Res., 324, 59-64.
33. Rabello, M.N., W. Becak, W.F. De Almeida, P. Pigati, M.T. Ungaro, T. Murata and C.A.B. Pereira (1975) Cytogenetic study on individuals occupationally exposed to DDT, Mutation Res., 28, 449-454.
34. Rojas, A. (1992) No increase in chromosome aberrations in lymphocytes from workers exposed to nitrogen fertilisers, Mutation Res., 281, 133-135.
35. Rupa, D.S., P.P. Reddy and O.S. Reddi (1989a) Frequencies of chromosomal aberrations in smokers exposed to pesticides in cotton fields, Mutation Res., 222, 37-41.
36. Rupa, D.S., P.P. Reddy and O.S. Reddi (1989b) Analysis of sister-chromatid exchanges, cell kinetics and mitotic index in lymphocytes of smoking pesticide sprayers. Mutation Res., 223, 253-258.
37. Rupa, D.S., P.P. Reddy and O.S. Reddi (1991a) Clastogenic effect of pesticides in peripheral lymphocytes of cotton-field workers, Mutation Res., 261, 177-180.
38. Rupa, D.S., P.P. Reddy, K. Sreemannarayana and O.S. Reddi (1991b) Frequency of sister chromatid exchange in peripheral lymphocytes of male pesticide applicators. Environ. Mol. Mutagen., 18, 136-138.
39. Sbrana, I. and A. Musio (1995) Enhanced expression of common fragile sites with pesticide exposure. Cancer Genet. Cytogenet., in press.
40. Scarabelli, L., P. Giannoni, C. Malfatto, C. Bolognesi and C.F. Cesarone (1993) Relationship between poly(ADP-ribose) polymerase activity and DNA damage induced by zinc dithiocarbamates in mouse and rat liver. Mutation Res., 302, 1-6.
41. See, R.H., B.P. Dunn and H.C. San (1990) Clastogenic activity in urine of workers occupationally exposed to pesticides, Mutation Res., 241, 251-259.
42. Steenland, K., M.S., A. Carrano, D. Clapp, J. Ratcliffe, L. Ashworth and T. Meinhardt (1985) Cytogenetic studies in humans after short-term exposure to ethylene dibromide, J. Occupat. Med., 27, 729-732.
43. Steenland, K., A. Carrano, J. Ratcliffe, D. Clapp, L. Ashworth and T. Meinhardt (1986) A cytogenetic study of papaya workers exposed to ethylene dibromide. Mutation Res., 170, 151-160.
44. Tompa, A., J. Major and M.G. Jakab (1994) Monitoring of benzene-exposed workers for genotoxic effects of benzene: improved-working-condition-related decrease in the frequencies of chromosomal aberrations in peripheral blood lymphocytes. Mutation Res., 304, 159-165.
45. Van Bao, T., I. Szabò, P. Ruzicska and A. Czeizel (1974) Chromosome aberrations in patients suffering acute organic phosphate insecticide intoxication, Humangenetik, 24, 33-57.
46. Vijayaraghavan, M. and B. Nagarajan (1994) Mutagenic potential of acute exposure to organophosphorus and organochlorine compounds. Mutation Res., 321, 103-111.
47. Yager, J.W., W.M. Paradisin, E. Symanski and S.M. Rappaport (1990) Sister Chromatid Exchanges induced in peripheral lymphocytes of workers exposed to low concentrations of styrene, Mutation and the Environment Part C. 347-356.
48. Yoder, J., M. Watson and W.W. Benson (1973) Lymphocyte chromosome analysis of agricultural workers during extensive occupational exposure to pesticides. Mutation Res., 21, 335-340.