-
1
-
-
0037340779
-
Insulin sensitization in the treatment of type 2 diabetes
-
J
-
Tadayyon M, Smith S A. Insulin sensitization in the treatment of type 2 diabetes[J]. Expert Opin Investing Drugs, 2003, 12:307-24.
-
(2003)
Expert Opin Investing Drugs
, vol.12
, pp. 307-324
-
-
Tadayyon, M.1
Smith, S.A.2
-
2
-
-
22344434266
-
The function genomics in drug-target research
-
J
-
Wang Y, Wang H. The function genomics in drug-target research [J]. Chin Pharma Bull, 2005, 21(5):266-8.
-
(2005)
Chin Pharma Bull
, vol.21
, Issue.5
, pp. 266-268
-
-
Wang, Y.1
Wang, H.2
-
3
-
-
1542791635
-
Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase
-
J
-
Kamata K, Mitsuya M, Nishimura T, et al. Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase[J]. Structure, 2004, 12(3):429-38.
-
(2004)
Structure
, vol.12
, Issue.3
, pp. 429-438
-
-
Kamata, K.1
Mitsuya, M.2
Nishimura, T.3
-
4
-
-
0017661504
-
Effect of burn trauma on glucose tunover, oxidation, and recycling in guinea pigs
-
J
-
Wolfe R R, Burke J F. Effect of burn trauma on glucose tunover, oxidation, and recycling in guinea pigs[J]. Am J Physiol, 1977, 233(2):E80-5.
-
(1977)
Am J Physiol
, vol.233
, Issue.2
-
-
Wolfe, R.R.1
Burke, J.F.2
-
5
-
-
2142661617
-
Two birds with one stone: Novel glucokinase activator stimulates glucose-induced pancreatic insulin secretion and augments hepatic glucose metabolism
-
J
-
Al-Hasani H, Tschopl M H, Cushman S W. Two birds with one stone: Novel glucokinase activator stimulates glucose-induced pancreatic insulin secretion and augments hepatic glucose metabolism [J]. Mol Interv, 2003, 3(7):367-70.
-
(2003)
Mol Interv
, vol.3
, Issue.7
, pp. 367-370
-
-
Al-Hasani, H.1
Tschopl, M.H.2
Cushman, S.W.3
-
6
-
-
14644394924
-
Glucokinase and glucose homoestasis: Proven concepts and new ideas
-
J
-
Zelent D, Najafi S H, Odili S, et al. Glucokinase and glucose homoestasis: proven concepts and new ideas[J]. Biochem Soc Trans, 2005, 33(pl):306-10.
-
(2005)
Biochem Soc Trans
, vol.33
, Issue.PL
, pp. 306-310
-
-
Zelent, D.1
Najafi, S.H.2
Odili, S.3
-
7
-
-
0023850224
-
Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats
-
J
-
Iynedjian P B, Gjinovci A, Renold A E. Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats[J]. J Biol Chem, 1988, 263:740-4.
-
(1988)
J Biol Chem
, vol.263
, pp. 740-744
-
-
Iynedjian, P.B.1
Gjinovci, A.2
Renold, A.E.3
-
8
-
-
0030956626
-
Modulation of glucose responsiveness of insulinoma beta-cells by graded overexpression of glucokinase
-
J
-
Wang H, Iynedjian P B. Modulation of glucose responsiveness of insulinoma beta-cells by graded overexpression of glucokinase[J]. Proc Nat Acad Sci, 1997, 94:4372-7.
-
(1997)
Proc Nat Acad Sci
, vol.94
, pp. 4372-4377
-
-
Wang, H.1
Iynedjian, P.B.2
-
9
-
-
0018630594
-
Effects of fructose concentration on carbohydrate metabolism, heat production and substrate cycling in isolated rat hepatocytes
-
J
-
Clark D G, Filsell O H, Topping D L, et al. Effects of fructose concentration on carbohydrate metabolism, heat production and substrate cycling in isolated rat hepatocytes[J]. Biochem J, 1979, 184:501-7.
-
(1979)
Biochem J
, vol.184
, pp. 501-507
-
-
Clark, D.G.1
Filsell, O.H.2
Topping, D.L.3
-
10
-
-
0024543929
-
A protein from rat liver confers to glucokinase the property of being antagonistically regulated by fructose 6-phosphate and fructose 1-phosphate
-
J
-
Van Schaftingen E. A protein from rat liver confers to glucokinase the property of being antagonistically regulated by fructose 6-phosphate and fructose 1-phosphate[J]. Eur J Biochem, 1989, 179:179-84.
-
(1989)
Eur J Biochem
, vol.179
, pp. 179-184
-
-
Van Schaftingen, E.1
-
11
-
-
0032929963
-
Effects of vanadium complexes with organic ligands on glucose metabolism: A comparison study in diabetic rats
-
J
-
Reul B A, Amin S S, Buchet J P, et al. Effects of vanadium complexes with organic ligands on glucose metabolism: a comparison study in diabetic rats[J]. Br J Pharmacol, 1999, 126:467-77.
-
(1999)
Br J Pharmacol
, vol.126
, pp. 467-477
-
-
Reul, B.A.1
Amin, S.S.2
Buchet, J.P.3
-
12
-
-
0030050853
-
Oral selenate improves glucose homeostasis and partly reverse abnormal expression of liver glycolytic and gluconeogenic enzymes in diabetic rats
-
J
-
Becker D J, Reul B, Ozcelikay A T. Oral selenate improves glucose homeostasis and partly reverse abnormal expression of liver glycolytic and gluconeogenic enzymes in diabetic rats[J]. Diabetologia, 1996, 39:3-11.
-
(1996)
Diabetologia
, vol.39
, pp. 3-11
-
-
Becker, D.J.1
Reul, B.2
Ozcelikay, A.T.3
-
13
-
-
0032588988
-
Effects of a beta 3-adrenergic agonist on liver glucokinase gene expression in alloxan diabetic rats
-
J
-
Milagro F I, Gez A J, Martez A E, et al. Effects of a beta 3-adrenergic agonist on liver glucokinase gene expression in alloxan diabetic rats[J]. J Physiol Biochem, 1999, 55:25-31.
-
(1999)
J Physiol Biochem
, vol.55
, pp. 25-31
-
-
Milagro, F.I.1
Gez, A.J.2
Martez, A.E.3
-
14
-
-
0032768616
-
Glucagon-like peptide-1 promote DNA synthesis, activates phosphatidylipositol 3-kinase and increase transcription factor pancreatic and duodenal homelbox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells
-
J
-
Buteeu J, Roduit R, Susini S, et al. Glucagon-like peptide-1 promote DNA synthesis, activates phosphatidylipositol 3-kinase and increase transcription factor pancreatic and duodenal homelbox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells[J]. Diabetologia, 1999, 42:856-64.
-
(1999)
Diabetologia
, vol.42
, pp. 856-864
-
-
Buteeu, J.1
Roduit, R.2
Susini, S.3
-
15
-
-
9444234554
-
Effect of biotin on glucokinase activity, mRNA expression and insulin release in cultured beta-cells
-
J
-
Borboni P, Magnaterra R, Rabini R A, et al. Effect of biotin on glucokinase activity, mRNA expression and insulin release in cultured beta-cells[J]. Acta Diabetol, 1996, 33:154-8.
-
(1996)
Acta Diabetol
, vol.33
, pp. 154-158
-
-
Borboni, P.1
Magnaterra, R.2
Rabini, R.A.3
-
16
-
-
0037624071
-
Allosteric activators of glucokinase: Potential role in diabetes therapy
-
J
-
Grimsby J, Sarabu R, Corbett W L, et al. Allosteric activators of glucokinase: potential role in diabetes therapy[J]. Science, 2003, 301(5631):370-3.
-
(2003)
Science
, vol.301
, Issue.5631
, pp. 370-373
-
-
Grimsby, J.1
Sarabu, R.2
Corbett, W.L.3
-
17
-
-
10744224346
-
Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators
-
J
-
Brocklehurst K J, Payne V A, Davies R A, et al. Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators[J]. Diabetes, 2004, 53:535-41.
-
(2004)
Diabetes
, vol.53
, pp. 535-541
-
-
Brocklehurst, K.J.1
Payne, V.A.2
Davies, R.A.3
-
18
-
-
0032556969
-
Familial hyperinsulinism caused by an activating glucokinase mutation
-
J
-
Glaser B, Kesavan P, Heyman M, et al. Familial hyperinsulinism caused by an activating glucokinase mutation[J]. N Engl J Med, 1998, 338:226-30.
-
(1998)
N Engl J Med
, vol.338
, pp. 226-230
-
-
Glaser, B.1
Kesavan, P.2
Heyman, M.3
-
19
-
-
0036227541
-
The second activating glucokinase mutation (A456V): Implications for glucose homeostasis and therapy
-
J
-
Christesen H B, Jacobsen B B, Odili S, et al. The second activating glucokinase mutation (A456V): implications for glucose homeostasis and therapy[J]. Diabetes, 2002, 51:1240-6.
-
(2002)
Diabetes
, vol.51
, pp. 1240-1246
-
-
Christesen, H.B.1
Jacobsen, B.B.2
Odili, S.3
-
20
-
-
0033979290
-
Study of the regulatory properties of glucokinase by site-directed mutagenesis: Conversion of glucokinase to an enzyme with high affinity for glucose
-
J
-
Moukil M A, Veiga-da-Cunha M, Van Schaftingen E. Study of the regulatory properties of glucokinase by site-directed mutagenesis: conversion of glucokinase to an enzyme with high affinity for glucose [J]. Diabetes, 2000, 49:195-201.
-
(2000)
Diabetes
, vol.49
, pp. 195-201
-
-
Moukil, M.A.1
Veiga-da-Cunha, M.2
Van Schaftingen, E.3
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