Screening and characterization of variant theta-class glutathione transferases catalyzing the activation of ethylene dibromide to a mutagen

Environmental and Molecular Mutagenesis

Volumn 47, Issue 9, 2006, Pages 657-665

  Josephy, P David ^a   Taylor, Patricia L ^a,c   Vervaet, Gaby ^a   Mannervik, Bengt ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b UPPSALA UNIVERSITY   (Sweden)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Escherichia coli; Ethylene dibromide; Glutathione transferase; Hexa histidine tagging; lacZ; Mutagenicity

Indexed keywords

1,2 DIBROMOETHANE; ENVIRONMENTAL MUTAGEN; ENZYME VARIANT; GLUTATHIONE; GLUTATHIONE TRANSFERASE T1; HISTIDINE; NICKEL; RECOMBINANT ENZYME;

AFFINITY CHROMATOGRAPHY; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME PURIFICATION; ESCHERICHIA COLI; HUMAN; LACTOSE OPERON; LACZ GENE; MUTAGEN TESTING; MUTAGENIC ACTIVITY; MUTAGENICITY; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERTANT; SEQUENCE ANALYSIS;

ANIMALS; CATALYSIS; ESCHERICHIA COLI; ETHYLENE DIBROMIDE; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; LAC OPERON; MUTAGENICITY TESTS; MUTAGENS; RATS; RECOMBINANT PROTEINS;

ESCHERICHIA COLI;

EID: 33845475482     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20252     Document Type: Article

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