Activation of dihaloalkanes by thiol-dependent mechanisms

Journal of Biochemistry and Molecular Biology

Volumn 36, Issue 1, 2003, Pages 20-27

  Guengerich, F Peter ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bioactivation; Dihalomethanes; Ethylene dibromide; Glutathione; Mutations; O6 Alkylguanine transferase

Indexed keywords

1,2 DIBROMOETHANE; ALKANE DERIVATIVE; GLUTATHIONE; METHANE; THIOL DERIVATIVE; TRANSFERASE; HALOGENATED HYDROCARBON; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE;

CHEMICAL ANALYSIS; CHEMICAL REACTION; CONJUGATION; COVALENT BOND; CYTOTOXICITY; DNA ADDUCT; DNA REPAIR; GENOTOXICITY; OXIDATION; PROTEIN ANALYSIS; REGULATORY MECHANISM; REVIEW; TOXICITY; CHEMISTRY; DRUG DETOXIFICATION; HUMAN; METABOLISM;

DNA ADDUCTS; ETHYLENE DIBROMIDE; GLUTATHIONE; HUMANS; HYDROCARBONS, HALOGENATED; METABOLIC DETOXICATION, DRUG; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; SULFHYDRYL COMPOUNDS;

EID: 0038544198     PISSN: 12258687     EISSN: None     Source Type: Journal    
DOI: 10.5483/bmbrep.2003.36.1.020     Document Type: Review

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