Brominated cyclodipeptides from the marine sponge Geodia barretti as selective 5-HT ligands

Journal of Natural Products

Volumn 69, Issue 10, 2006, Pages 1421-1424

  Hedner, Erik ^a   Sjögren, Martin ^a   Frändberg, Per Anders ^a   Johansson, Tobias ^a   Göransson, Ulf ^a   Dahlström, Mia ^b   Jonsson, Per ^b   Nyberg, Fred ^a   Bohlin, Lars ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b GÖTEBORG UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

8,9 DIHYDROBARETTIN; ARGININE; BARETTIN; DIPEPTIDE DERIVATIVE; SEROTONIN; SEROTONIN 2A RECEPTOR; SEROTONIN 2C AGONIST; SEROTONIN 4 RECEPTOR; SEROTONIN RECEPTOR; TEGASEROD; TRYPTOPHAN;

ARTICLE; BINDING AFFINITY; BROMINATION; CELL MEMBRANE; CELL STRAIN HEK293; CONTROLLED STUDY; DOSE RESPONSE; DRUG ISOLATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; GEODIA; GEODIA BARRETTI; HUMAN; HUMAN CELL; HYDROXYLATION; MINIMUM INHIBITORY CONCENTRATION; RECEPTOR AFFINITY; SPONGE (PORIFERA); STRUCTURE ACTIVITY RELATION;

ANIMALS; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROCARBONS, BROMINATED; KIDNEY; LARVA; MARINE BIOLOGY; MOLECULAR STRUCTURE; PEPTIDES, CYCLIC; PORIFERA; RECEPTORS, SEROTONIN; THORACICA;

GEODIA BARRETTI; THORACICA;

EID: 33845428430     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np0601760     Document Type: Article

References (19)

1. Mayer, A. M.; Hamann, M. T. Mar. Biotechnol. 2004, 6, 37-52.
2. Newman, D. J.; Cragg, G. M. J. Nat. Prod. 2004, 67, 1216-1238.
3. Proksch, P. Toxicon. 1994, 32, 639-655.
4. Sjögren, M.; Dahlström, M.; Göransson, U.; Jonsson, P. R.; Bohlin, L. Biofouling 2004, 20, 291-297.
5. Sjögren, M.; Göransson, U.; Johnson, A. L.; Dahlström, M.; Andersson, R.; Bergman, J.; Jonsson, P. R.; Bohlin, L. J. Nat. Prod. 2004, 67, 368-372.
6. Johnson, A. L.; Bergman, J.; Sjögren, M.; Bohlin, L. Tetrahedron 2004, 60, 961-965.
7. Sölter, S.; Dieckmann, R.; Blumenberg, M.; Francke, W. Tetrahedron Lett. 2002, 43, 3385-3386.
8. England, L. J.; Imperial, J.; Jacobsen, R.; Craig, A. G.; Gulyas, J.; Akhtar, M.; Rivier, J.; Julius, D.; Olivera, B. M. Science 1998, 281, 575-578.
9. Beglinger, C. Int. J. Clin. Pract. 2002, 56, 47-51.
10. Bozsing, D.; Simonek, I.; Simig, G.; Jakoczi, I.; Gacsalyi, I.; Levay, G.; Tihanyi, K.; Schmidt, E. Bioorg. Med. Chem. Lett. 2002, 12, 3097-3099.
11. Smith, B. M.; Smith, J. M.; Tsai, J. H.; Schultz, J. A.; Gilson, C. A.; Estrada, S. A.; Chen, R. R.; Park, D. M.; Prieto, E. B.; Gallardo, C. S.; Sengupta, D.; Thomsen, W. J.; Saldana, H. R.; Whelan, K. T.; Menzaghi, F.; Webb, R. R.; Beeley, N. R. Bioorg. Med. Chem. Lett. 2005, 15, 1467-1470.
12. Tierney, A. J. Comp. Biochem. Physiol., Part A: Mol. Integr. Physiol. 2001, 128, 791-804.
13. Colas, J. F.; Choi, D. S.; Launay, J. M.; Maroteaux, L. Ann. NY Acad. Sci. 1997, 812, 149-153.
14. Witz, P.; Amlaiky, N.; Plassat, J. L.; Maroteaux, L.; Borrelli, E.; Hen, R. Proc. Natl. Acad. Sci. U.S.A. 1990, 87, 8940-8944.
15. Kawahara, H.; Isoai, A.; Shizuri, Y. Gene 1997, 184, 245-250.
16. Clark, M. C.; Dever, T. E.; Dever, J. J.; Xu, P.; Render, V.; Sosa, M. A.; Baro, D. J. J. Neurosci. 2004, 24, 3421-3435.
17. Johanson, J. F. Aliment Pharmacol. Ther. 2004, 20, Suppl. 7, 20-24.
18. Beattie, D. T.; Smith, J. A.; Marquess, D.; Vickery, R. G.; Armstrong, S. R.; Pulido-Rios, T.; McCullough, J. L.; Sandlund, C.; Richardson, C.; Mai, N.; Humphrey, P. P. Br. J. Pharmacol. 2004, 143, 549-560.
19. Cheng, Y.; Prusoff, W. H. Biochem. Pharmacol. 1973, 22, 3099-3108.