Trp53 affects the developmental anomaly of clefts of the palate in irradiated mouse embryos but not clefts of the lip with or without the palate

Radiation Research

Volumn 166, Issue 6, 2006, Pages 877-882

  Narai, Shota ^a   Kodama, Yasumitsu ^a   Maeda, Yoshitaka ^b   Yokoyama, Minesuke ^b   Takagi, Ritsuo ^a   Kominami, Ryo ^a,b  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CESIUM 137; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLEFT LIP PALATE; CLEFT PALATE; CRANIOFACIAL MALFORMATION; EMBRYO; EMBRYO DEVELOPMENT; GAMMA IRRADIATION; GENOTYPE; IRRADIATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

ANIMALS; CLEFT LIP; CLEFT PALATE; EMBRYO; FEMALE; MICE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33845350208     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR0644.1     Document Type: Article

References (30)

1. P. Stanier and G. E. Moore, Genetics of cleft lip and palate: Syndromic genes contribute to the incidence of non-syndromic clefts. Hum. Mol. Genet. 13 (Review Issue 1), R73-R81 (2004).
2. A. P. Vanderas, Incidence of cleft lip, cleft palate, and cleft lip and palate among races: A review. Cleft Palate J. 24, 216-225 (1987).
3. J. C. Murray, Gene/environment causes of cleft lip and/or palate. Clin. Genet. 61, 248-256 (2002).
4. J. C. Murray and B. C. Schutte, Cleft palate: Players, pathways, and pursuits. J. Clin. Invest. 113, 1676-1678 (2004).
5. S. Bornstein, D. G. Trasler and F. C. Fraser, Effect of the uterine environment on the frequency of spontaneous cleft lip in CL/FR mice. Teratology 3, 295-298 (1970).
6. D. M. Juriloff and F. C. Fraser, Genetic maternal effects on cleft lip frequency in A/J and CL/Fr mice. Teratology 21, 167-175 (1980).
7. G. Millicovsky, L. J. Ambrose and M. C. Johnston, Developmental alterations associated with spontaneous cleft lip and palate in CL/Fr mice. Am. J. Anat. 164, 29-44 (1982).
8. L. B. Russell and W. L. Russell, An analysis of the changing radiation response of the developing mouse embryo. J. Cell Physiol. 43, 103-149 (1954).
9. G. Callas and B. E. Walker, Palate morphogenesis in mouse embryos after x-irradiation. Anat. Rec. 145, 61-71 (1963).
10. A. J. Giaccia and M. B. Kastan, The complexity of p53 modulation: Emerging patterns from divergent signals. Genes Dev. 12, 2973-2983 (1998).
11. P. Fei and W. S. El-Deiry, P53 and radiation responses. Oncogene 22, 5774-5783 (2003).
12. V. P. Sah, L. D. Attardi, G. J. Mulligan, B. O. Williams, R. T. Bronson and T. Jacks, A subset of p53-deficient embryos exhibit exencephaly. Nat. Genet. 10, 175-180 (1995).
13. J. F. Armstrong, M. H. Kaufman, D. J. Harrison and A. R. Clarke, High-frequency developmental abnormalities in p53-deficient mice. Curr. Biol. 5, 931-936 (1995).
14. T. Norimura, S. Nomoto, M. Katsuki, Y. Gondo and S. Kondo, p53-dependent apoptosis suppresses radiation-induced teratogenesis. Nat. Med. 2, 577-580 (1996).
15. +/- mice to malformation after foetal irradiation is related to sub-competent apoptosis. Int. J. Radiat. Biol. 74, 419-429 (1998).
16. P Markel, R Shu, C. Ebeling, G. A. Carlson, D. L. Nagle, J. S. Smutko and K. J. Moore, Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains. Nat. Genet. 17, 280-284 (1997).
17. M. Nagata, N. Amin, Y. Kannari, M. Hayatsu, Y. Ohashi and A. Oguro, Isolated maxillary bending in CL/FR strain mice: Observation of craniofacial deformity and inheritance pattern. Cleft Palate Craniofac. J. 34, 101-105 (1997).
18. T. Kubota, Y. Yoshikai, Y. Tamura, Y. Mishima, Y. Aoyagi, O. Niwa and R. Kominami, Comparison of properties of spontaneous and radiation-induced mouse thymic lymphomas: Role of Trp53 and radiation. Radiat. Res. 163, 159-164 (2005).
19. Y. Wakabayashi, H. Watanabe, J. Inoue, N. Takeda, J. Sakata, Y Mishima, J. Hitomi, T. Yamamoto, M. Utsuyama and R. Kominami, Bcl1 1b is required for differentiation and survival of αβ T lymphocytes. Nat. Immunol. 4, 533-539 (2003).
20. C. Martínez-Álvarez, C. Tudela, J. Pérez-Miguelsanz, S. O'Kane, J. Puerta and M. W. Ferguson, Medial edge epithelial cell fate during palatal fusion. Dev. Biol. 220, 343-357 (2000).
21. R. Jiang, J. O. Bush and A. C. Lidral, Development of the upper lip: Morphogenetic and molecular mechanisms. Dev. Dyn. 235, 1125-1166 (2005).
22. S. G. Gong and C. Guo, Bmp4 gene is expressed at the putative site of fusion in the midfacial region. Differentiation 71, 228-236 (2003).
23. E. D. Hay, The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it. Dev. Dyn. 233, 706-720 (2005).
24. F. Vaziri Sani, K. Hallberg, B. D. Harfe, A. R McMahon, A. Linde and A. Gritli-Linde, Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation. Dev. Biol. 285, 490-495 (2005).
25. R. Cuervo and L. Covarrubias, Death is the major fate of medial edge epithelial cells and the cause of basal lamina degradation during palatogenesis. Development 131, 15-24 (2004).
26. A. Nawshad and E. D. Hay, TGFβ3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development. J. Cell Biol. 163, 1291-1301 (2003).
27. D. G. Trasler and L. Ohannessian, Ultrastructure of initial nasal process cell fusion in spontaneous and 6-aminonicotinamide-induced mouse embryo cleft lip. Teratology 28, 91-101 (1983).
28. B. Wang, H. Ohyama, K. Haginoya, T. Odaka, T. Yamada and I. Hayata, Prenatal radiation-induced limb defects mediated by Trp53-dependent apoptosis in mice. Radiat. Res. 154, 673-679 (2000).
29. S. Venkatachalam, Y. P. Shi, S. N. Jones, H. Vogel, A. Bradley, D. Pinkel and L. A. Donehower, Retention of wild-type p53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation. EMBO J. 17, 4657-4667 (1998).
30. W. D. Cook and B. J. McCaw, Accommodating haploinsufficient tumor suppressor genes in Knudson's model. Oncogene 19, 3434-3438 (2000).