3D pharmacophore based virtual screening of T-type calcium channel blockers

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 2, 2007, Pages 1091-1105

  Doddareddy, Munikumar Reddy ^a   Choo, Hyunah ^a   Cho, Yong Seo ^a   Rhim, Hyewhon ^a   Koh, Hun Yeong ^a   Lee, Jung Ha ^b   Jeong, Seong Woo ^c   Pae, Ae Nim ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Sogang University   (South Korea)

^c Yonsei University Wonju   (South Korea)

Author keywords

Pharmacophore; T type calcium channel blockers; Virtual screening

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; MIBEFRADIL; T TYPE CALCIUM CHANNEL BLOCKER;

ANIMAL CELL; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHARMACOPHORE;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, N-TYPE; CALCIUM CHANNELS, T-TYPE; CATALYSIS; CELL LINE; COMPUTER SIMULATION; DATABASES, FACTUAL; ELECTROPHYSIOLOGY; HUMANS; MIBEFRADIL; MODELS, MOLECULAR; OOCYTES; PATCH-CLAMP TECHNIQUES; RNA, COMPLEMENTARY; XENOPUS;

EID: 33845339664     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.10.013     Document Type: Article

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