Molecular determinants of high affinity phenylalkylamine block of L- type calcium channels in transmembrane segment IIIS6 and the pore region of the α1 subunit

Journal of Biological Chemistry

Volumn 272, Issue 30, 1997, Pages 18759-18765

  Hockerman, Gregory H ^a   Johnson, Barry D ^a   Abbott, Michael R ^a   Scheuer, Todd ^a   Catterall, William A ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; PHENYLALKYLAMINE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM TRANSPORT; HUMAN; HUMAN CELL; MEMBRANE BINDING; MEMBRANE TRANSPORT; MOLECULAR DYNAMICS; PRIORITY JOURNAL; VOLTAGE CLAMP;

ACTION POTENTIALS; AMINO ACID SEQUENCE; BINDING SITES; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; CELL MEMBRANE; CELLS, CULTURED; GLUTAMINE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; STRUCTURE-ACTIVITY RELATIONSHIP; VERAPAMIL;

EID: 0030839794     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.30.18759     Document Type: Article

References (33)

1. Snutch, T. P., and Reiner, P. B. (1992) Curr. Opin. Neurobiol. 2, 247-253
2. Catterall, W. A. (1994) Curr. Opin. Cell Biol. 6, 607-615
3. Tanabe, T., Takeshima, H., Mikami, A., Flockerzi, V., Takahashi, H., Kangawa, K., Kojima, M., Matsuo, H., Hirose, T., and Numa, S. (1987) Nature 328, 313-318
4. Fleckenstein, A., and Fleckenstein-Grun, G. (1980) Eur. Heart J. 1, 15-21
5. Gould, R. J., Murphy, K. M., and Snyder, S. H. (1983) Cold Spring Harbor Symp. Quant. Biol. 48, 355-362
6. Glossmann, H., Ferry, D. R., Goll, A., Rombusch, M. (1984) J. Cardiovasc. Pharmacol. 6, (Suppl.) 508-521
7. Hockerman, G. H., Peterson, B. Z., Johnson, B. D., and Catterall, W. A. (1997) Annu. Rev. Pharmacol. Toxicol. 37, 361-396
8. Striessnig, J., Murphy, B. J., and Catterall, W. A. (1991) Proc. Natl. Acac. Sci. U. S. A. 88, 10769-10773
9. Grabner, M., Wang, Z., Hering, S., Striessnig, J., and Glossmann, H. (1996) Neuron 16, 207-218
10. Peterson, B. Z., Tanada, T. N., and Catterall, W. A. (1996) J. Biol. Chem. 271, 5293-5296
11. Kraus, R., Reichl, B., Kimball, S. D., Grabner, M., Murphy, B. J., Catterall, W. A., and Striessnig, J. (1996) J. Biol. Chem. 271, 20113-20118
12. Mitterdorfer, J., Wang, Z., Sinnegger, M. J., Hering, S., Striessnig, J., Grabner, M., and Glossmann, H. (1996) J. Biol. Chem. 271, 30330-30335
13. Striessnig, J., Glossmann, H., and Catterall, W. A. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 9108-9112
14. Hockerman, G. H., Johnson, B. D., Scheuer, T., and Catterall, W. A. (1995) J. Biol. Chem. 270, 22119-22122
15. Schuster, A., Lacinova, L., Klugbauer, N., Ito, H., Birnbaumer, L., and Hoffmann, F. (1996) EMBO J. 15, 2365-2370
16. Doring, F., Degtiar, V. E., Grabner, M., Striessnig, J., Hering, S., and Glossmann, H. (1996) J. Biol. Chem. 271, 11745-11749
17. Wit, A. L., and Cranefield, P. P. (1974) Circ. Res. 35, 413-425
18. Hescheler, J., Pelzer, D., Trube, G., and Trautwein, W. (1982) Pflügers Arch. Eur. J. Physiol. 393, 287-291
19. Pelzer, D., Trautwein, W., and McDonald, T. F. (1982) Pflügers Archi.v 394, 97-105
20. Yang, J., Ellinor, P. T., Sather, W. A., Zhang, J. F., and Tsien, R. W. (1993) Nature 366, 109-110
21. Kunkel, T. A. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 488-492
22. Snutch, T. P., Tomlinson, W. J., Leonard, J. P., and Gilbert, M. M. (1991) Neuron 7, 45-57
23. Pragnell, M., Sakamoto, J., Jay, S. D., and Campbell, K. P. (1991) FEBS Lett. 291, 253-258
24. Ellis, S. B., Williams, M. E., Ways, N. R., Brenner, R., Sharp, A. H., Leung, A. T., Campbell, K. P., McKenna, E., Koch, W. J., Hui, A., Schwartz, A., and Harpold, M. M. (1988) Science 241, 1661-1664
25. Margolskee, R. F., McHendry-Rinde, B., and Horn, R. (1994) BioTechniques 15, 906-911
26. Blaber, M., Zhang, K. J., and Matthews, B. W. (1993) Science 260, 1637-1640
27. Ehara, T., and Kaufmann, R. (1978) J. Pharmacol. Exp. Ther. 207, 49-55
28. McDonald, T. F., Pelzer, D., and Trautwein, W. (1984) J. Physiol. (Lond.) 352, 217-241
29. Johnson, B. D., Hockerman, G. H., Scheuer, T., and Catterall, W. A. (1996) Mol. Pharmacol. 50, 1388-1400
30. Tang, S., Mikala, G., Bahinski, A., Yatani, A., Varadi, G., and Schwartz, A. (1993) J. Biol. Chem. 268, 13026-13029
31. DeCoursey, T. E. (1995) J. Gen. Physiol. 106, 745-779
32. Catterall, W. A., and Striessnig, J. (1992) Trends Pharmacol. Sci. 13, 256-262
33. Peterson, B. Z., Johnson, B. D., Hockerman, G. H., Acheson, M. J., Scheuer, T., and Catterall, W. A. (1997) J. Biol. Chem. 272, 18752-18758