메뉴 건너뛰기




Volumn 6, Issue 4, 1997, Pages 257-265

Oltipraz chemoprevention trial in Qidong, People's Republic of China: Study design and clinical outcomes

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN; OLTIPRAZ;

EID: 16944362010     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (114)

References (26)
  • 1
    • 0002431221 scopus 로고
    • Hepatocellular carcinoma in Qidong County
    • Z. Y. Tang (ed.). Beijing: Springer Verlag
    • Zhu, Y-R., Chen, J-G., and Huang, X. Y. Hepatocellular carcinoma in Qidong County. In: Z. Y. Tang (ed.). Primary Liver Cancer, pp. 204-222. Beijing: Springer Verlag, 1989.
    • (1989) Primary Liver Cancer , pp. 204-222
    • Zhu, Y.-R.1    Chen, J.-G.2    Huang, X.Y.3
  • 2
    • 0028818446 scopus 로고
    • Primary prevention of hepatocellular carcinoma
    • Yu, S-Z. Primary prevention of hepatocellular carcinoma. J. Gastroenterol. Hepatol., 10: 674-682, 1995.
    • (1995) J. Gastroenterol. Hepatol. , vol.10 , pp. 674-682
    • Yu, S.-Z.1
  • 5
    • 16944364233 scopus 로고
    • Hepatocellular carcinoma caused by hepatitis B virus
    • A. S. Evans (ed.). New York: Plenum Press
    • Melnick, J. L. Hepatocellular carcinoma caused by hepatitis B virus. In: A. S. Evans (ed.). Viral Infections of Humans. Epidemiology and Control, 3rd Ed., pp. 769-780. New York: Plenum Press, 1989.
    • (1989) Viral Infections of Humans. Epidemiology and Control, 3rd Ed. , pp. 769-780
    • Melnick, J.L.1
  • 6
    • 0030006616 scopus 로고    scopus 로고
    • Detection of microcystins, a blue-green algal hepatotoxin, in drinking water sampled in Haimen and Fusui, endemic areas of primary liver cancer in China, by highly sensitive immunoassay
    • Ueno, Y., Nagata, S., Tsutsumi, T., Hasegawa, A., Watanabe, M. F., Park, H-D., Chen, G-C., Chen, G., and Yu, S-Z. Detection of microcystins, a blue-green algal hepatotoxin, in drinking water sampled in Haimen and Fusui, endemic areas of primary liver cancer in China, by highly sensitive immunoassay. Carcinogenesis (Lond.), 17: 1317-1321, 1996.
    • (1996) Carcinogenesis (Lond.) , vol.17 , pp. 1317-1321
    • Ueno, Y.1    Nagata, S.2    Tsutsumi, T.3    Hasegawa, A.4    Watanabe, M.F.5    Park, H.-D.6    Chen, G.-C.7    Chen, G.8    Yu, S.-Z.9
  • 8
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt, M. S., Bennett, W. P., Hollstein, M., and Harris, C. C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 54: 4855-4878, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 9
    • 0027337609 scopus 로고
    • 1 induces the transversion of G to T in codon 249 of the p53 tumor suppressor gene in human hepatocytes
    • 1 induces the transversion of G to T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc. Natl. Acad. Sci. USA, 90: 8586-8590, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8586-8590
    • Aguilar, F.1    Hussain, S.P.2    Cerutti, P.3
  • 10
    • 0025925257 scopus 로고
    • 1-induced hepatocarcinogenesis in rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): Predictive role for short-term molecular dosimetry
    • 1-induced hepatocarcinogenesis in rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): predictive role for short-term molecular dosimetry. Cancer Res., 51: 5501-5506, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 5501-5506
    • Roebuck, B.D.1    Liu, Y.-L.2    Rogers, A.E.3    Groopman, J.D.4    Kensler, T.W.5
  • 11
    • 0027377850 scopus 로고
    • Cancer chemoprevention by Oltipraz: Experimental and clinical considerations
    • Helzlsouer, K. J., and Kensler, T. W. Cancer chemoprevention by Oltipraz: experimental and clinical considerations. Prev. Med., 22: 783-795, 1993.
    • (1993) Prev. Med. , vol.22 , pp. 783-795
    • Helzlsouer, K.J.1    Kensler, T.W.2
  • 12
    • 0029048396 scopus 로고
    • Intermittent dosing with oltipraz: Relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases
    • Primiano, T., Egner, P. A., Suiter, T. R., Kelloff, G. J., Roebuck, B. D., and Kensler, T. W. Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases. Cancer Res., 55: 4319-4324, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 4319-4324
    • Primiano, T.1    Egner, P.A.2    Suiter, T.R.3    Kelloff, G.J.4    Roebuck, B.D.5    Kensler, T.W.6
  • 14
    • 0029111905 scopus 로고
    • Levels of aflatoxin-albumin biomarkers in rat plasma are modulated by both long-term and transient interventions with oltipraz
    • Egner, P. A., Gange, S. J., Dolan, P. M., Groopman, J. D., Muñoz, A., and Kensler, T. W. Levels of aflatoxin-albumin biomarkers in rat plasma are modulated by both long-term and transient interventions with oltipraz. Carcinogenesis (Lond.), 16: 1769-1773, 1995.
    • (1995) Carcinogenesis (Lond.) , vol.16 , pp. 1769-1773
    • Egner, P.A.1    Gange, S.J.2    Dolan, P.M.3    Groopman, J.D.4    Muñoz, A.5    Kensler, T.W.6
  • 15
    • 0027102330 scopus 로고
    • Clinical pharmacology studies of oltipraz - A potential chemopreventive agent. Invest
    • Dimitrov, N. V., Bennett, J. L., McMillan, J., Perloff, M., Leece, C. M., and Malone, W. Clinical pharmacology studies of oltipraz - a potential chemopreventive agent. Invest. New Drugs, 10: 289-298, 1992.
    • (1992) New Drugs , vol.10 , pp. 289-298
    • Dimitrov, N.V.1    Bennett, J.L.2    McMillan, J.3    Perloff, M.4    Leece, C.M.5    Malone, W.6
  • 16
    • 0027362312 scopus 로고
    • Oltipraz: A laboratory and clinical review
    • Benson, A. B., III. Oltipraz: a laboratory and clinical review. J. Cell. Biochem., 17F: 278-291, 1993.
    • (1993) J. Cell. Biochem. , vol.17 F , pp. 278-291
    • Benson III, A.B.1
  • 19
    • 0025978524 scopus 로고
    • A method for the detection and management of adverse events in clinical trials
    • Tangrea, J. A., Adrianza, M. E., and McAdams, M. A method for the detection and management of adverse events in clinical trials. Drug Information J., 25: 63-80, 1991.
    • (1991) Drug Information J. , vol.25 , pp. 63-80
    • Tangrea, J.A.1    Adrianza, M.E.2    McAdams, M.3
  • 20
    • 0004248046 scopus 로고
    • New York: John Wiley & Sons, Inc.
    • Miller, R. G. Survival Analysis, pp. 143-146. New York: John Wiley & Sons, Inc., 1981.
    • (1981) Survival Analysis , pp. 143-146
    • Miller, R.G.1
  • 23
    • 0019134347 scopus 로고
    • Assessment of 35972 RP (Oltipraz), a new antischistosomal drug against Schistosoma haematobium, Schistosoma mansoni, and Schistosoma intercalatum
    • Gentilini, M., Duflo, B., Richard-Lenoble, D., Brücker, G., Danis, M., Niel, G., and Muenier, Y. Assessment of 35972 RP (Oltipraz), a new antischistosomal drug against Schistosoma haematobium, Schistosoma mansoni, and Schistosoma intercalatum. Acta Trop., 37: 271-274, 1980.
    • (1980) Acta Trop. , vol.37 , pp. 271-274
    • Gentilini, M.1    Duflo, B.2    Richard-Lenoble, D.3    Brücker, G.4    Danis, M.5    Niel, G.6    Muenier, Y.7
  • 25
    • 0020472320 scopus 로고
    • Dose-ranging clinical trial with Oltipraz in Schistosomiasis mansoni
    • Katz, N., Rocha, R. S., and Chaves, A. Dose-ranging clinical trial with Oltipraz in Schistosomiasis mansoni. Rev. Inst. Med. Trop. São Paulo, 24: 40-48, 1982.
    • (1982) Rev. Inst. Med. Trop. São Paulo , vol.24 , pp. 40-48
    • Katz, N.1    Rocha, R.S.2    Chaves, A.3
  • 26
    • 0022407118 scopus 로고
    • Dose-finding trial using Oltipraz to treat schoolchildren infected with Schistosoma mansoni in Gezira, Sudan
    • Igail, A. B. E., Tayeb, M. E., Karadaman, M. W., Daffalla, A. A., Dixon, H. G., and Fenwick, A. Dose-finding trial using Oltipraz to treat schoolchildren infected with Schistosoma mansoni in Gezira, Sudan. J. Trop. Med. Hyg., 88: 101-104, 1985.
    • (1985) J. Trop. Med. Hyg. , vol.88 , pp. 101-104
    • Igail, A.B.E.1    Tayeb, M.E.2    Karadaman, M.W.3    Daffalla, A.A.4    Dixon, H.G.5    Fenwick, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.