Quinone methide formations in the Cu2+-induced oxidation of a diterpenone catechol and concurrent damage on DNA

Chemical Research in Toxicology

Volumn 18, Issue 2, 2005, Pages 382-388

  Zhou, Qibing ^a   Zuniga, Miguel A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL DERIVATIVE; COPPER; DITERPENONE CATECHOL; DOUBLE STRANDED DNA; HYDROXYL RADICAL; NUCLEIC ACID BASE; QUINONE DERIVATIVE; TERPENE DERIVATIVE; TERPENE QUINONE METHIDE DERIVATIVE; THIOL; UNCLASSIFIED DRUG;

ADDITION REACTION; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CATALYST; DNA CLEAVAGE; DNA DAMAGE; DNA DETERMINATION; DRUG CYTOTOXICITY; DRUG OXIDATION; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERIZATION;

CATECHOLS; COPPER; DITERPENES; DNA; DNA DAMAGE; INDOLEQUINONES; MOLECULAR CONFORMATION; OXIDATION-REDUCTION;

EID: 13844289443     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx049703a     Document Type: Article

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